DOP2017000096A - Uso del ácido neridrónico o de su sal para el tratamiento de la osteoartrosis - Google Patents

Uso del ácido neridrónico o de su sal para el tratamiento de la osteoartrosis

Info

Publication number
DOP2017000096A
DOP2017000096A DO2017000096A DO2017000096A DOP2017000096A DO P2017000096 A DOP2017000096 A DO P2017000096A DO 2017000096 A DO2017000096 A DO 2017000096A DO 2017000096 A DO2017000096 A DO 2017000096A DO P2017000096 A DOP2017000096 A DO P2017000096A
Authority
DO
Dominican Republic
Prior art keywords
salt
neridronic acid
treatment
osteoartrosis
osteoarthritis
Prior art date
Application number
DO2017000096A
Other languages
English (en)
Inventor
Massimo Varenna
Original Assignee
Abiogen Pharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51904075&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2017000096(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abiogen Pharma Spa filed Critical Abiogen Pharma Spa
Publication of DOP2017000096A publication Critical patent/DOP2017000096A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describe el uso del ácido neridrónico o una sal del mismo en el tratamiento de la osteoartritis. En particular, se ha demostrado que el ácido neridrónico o una sal del mismo es capaz de reducir significativamente los síntomas de la osteoartritis, tales como el dolor y las discapacidades físicas y de movilidad, al igual que las lesiones de la médula ósea subcondral subyacentes a la aparición de estos síntomas.
DO2017000096A 2014-10-15 2017-04-10 Uso del ácido neridrónico o de su sal para el tratamiento de la osteoartrosis DOP2017000096A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI20141794 2014-10-15

Publications (1)

Publication Number Publication Date
DOP2017000096A true DOP2017000096A (es) 2017-07-31

Family

ID=51904075

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2017000096A DOP2017000096A (es) 2014-10-15 2017-04-10 Uso del ácido neridrónico o de su sal para el tratamiento de la osteoartrosis

Country Status (32)

Country Link
US (2) US20170209470A1 (es)
EP (1) EP3206694B1 (es)
JP (1) JP6839076B2 (es)
KR (1) KR102591084B1 (es)
CN (2) CN111939164A (es)
AU (1) AU2015332060B2 (es)
BR (1) BR112017006989A2 (es)
CA (1) CA2963066C (es)
CL (1) CL2017000915A1 (es)
CO (1) CO2017003561A2 (es)
CY (1) CY1123420T1 (es)
DK (1) DK3206694T3 (es)
DO (1) DOP2017000096A (es)
EA (1) EA033191B1 (es)
EC (1) ECSP17023093A (es)
ES (1) ES2819186T3 (es)
HR (1) HRP20201475T1 (es)
HU (1) HUE052088T2 (es)
IL (1) IL251421B (es)
LT (1) LT3206694T (es)
MX (1) MX2017004826A (es)
MY (1) MY191481A (es)
NZ (1) NZ730853A (es)
PE (1) PE20170699A1 (es)
PH (1) PH12017500659A1 (es)
PL (1) PL3206694T3 (es)
PT (1) PT3206694T (es)
RS (1) RS60868B1 (es)
SG (1) SG11201702574XA (es)
SI (1) SI3206694T1 (es)
TN (1) TN2017000095A1 (es)
WO (1) WO2016059594A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190328755A1 (en) * 2018-04-30 2019-10-31 Grunenthal Gmbh Methods of treating complex regional pain syndrome (crps) or symptoms comprising administration of neridronic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20040218A1 (it) * 2004-02-10 2004-05-10 Abiogen Pharma Spa Uso di neridronato sodico per promuovere la neoformazione ossea
CA2565079A1 (en) * 2004-05-06 2005-11-17 Merck & Co., Inc. Methods for treating arthritic conditions in dogs
EP1988907A4 (en) * 2006-02-06 2010-04-14 Cypress Bioscience Inc COMPOSITIONS COMPRISING A BISPHOSPHONATE AND AN ANTIFOLATE
US20070191315A1 (en) * 2006-02-16 2007-08-16 Bengt Bergstrom Method for administering ibandronate

Also Published As

Publication number Publication date
AU2015332060B2 (en) 2018-06-07
CY1123420T1 (el) 2021-12-31
PE20170699A1 (es) 2017-06-03
US20230233585A1 (en) 2023-07-27
CN106794190A (zh) 2017-05-31
LT3206694T (lt) 2020-11-25
CA2963066A1 (en) 2016-04-21
SG11201702574XA (en) 2017-04-27
EA033191B1 (ru) 2019-09-30
ECSP17023093A (es) 2017-06-30
EA201790531A1 (ru) 2017-08-31
SI3206694T1 (sl) 2020-11-30
KR20170066438A (ko) 2017-06-14
AU2015332060A1 (en) 2017-04-27
EP3206694A1 (en) 2017-08-23
WO2016059594A1 (en) 2016-04-21
US20170209470A1 (en) 2017-07-27
JP6839076B2 (ja) 2021-03-03
IL251421B (en) 2022-05-01
JP2017532333A (ja) 2017-11-02
MY191481A (en) 2022-06-28
RS60868B1 (sr) 2020-11-30
PL3206694T3 (pl) 2020-12-28
HUE052088T2 (hu) 2021-04-28
MX2017004826A (es) 2018-01-24
TN2017000095A1 (en) 2018-07-04
NZ730853A (en) 2018-06-29
IL251421A0 (en) 2017-05-29
CO2017003561A2 (es) 2017-09-11
KR102591084B1 (ko) 2023-10-18
EP3206694B1 (en) 2020-07-08
PH12017500659A1 (en) 2017-10-02
DK3206694T3 (da) 2020-09-21
CN111939164A (zh) 2020-11-17
ES2819186T3 (es) 2021-04-15
BR112017006989A2 (pt) 2018-03-27
CL2017000915A1 (es) 2017-11-10
PT3206694T (pt) 2020-09-22
CA2963066C (en) 2023-12-05
HRP20201475T1 (hr) 2020-12-11

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