DK87687A - 1,6-naphthyridinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende dem - Google Patents

1,6-naphthyridinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende dem

Info

Publication number
DK87687A
DK87687A DK087687A DK87687A DK87687A DK 87687 A DK87687 A DK 87687A DK 087687 A DK087687 A DK 087687A DK 87687 A DK87687 A DK 87687A DK 87687 A DK87687 A DK 87687A
Authority
DK
Denmark
Prior art keywords
procedures
preparation
pharmaceutical preparations
preparations containing
naphthyridine derivatives
Prior art date
Application number
DK087687A
Other languages
Danish (da)
English (en)
Other versions
DK87687D0 (da
Inventor
Juergen Kleinschroth
Karl Mannhardt
Johannes Hartenstein
Gerhard Satzinger
Dieter Muster
Wolfgang Steinbrecher
Bernd Wagner
Hartmut Osswald
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of DK87687D0 publication Critical patent/DK87687D0/da
Publication of DK87687A publication Critical patent/DK87687A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK087687A 1984-08-25 1987-02-20 1,6-naphthyridinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende dem DK87687A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843431303 DE3431303A1 (de) 1984-08-25 1984-08-25 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE19863605743 DE3605743A1 (de) 1984-08-25 1986-02-22 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung

Publications (2)

Publication Number Publication Date
DK87687D0 DK87687D0 (da) 1987-02-20
DK87687A true DK87687A (da) 1987-08-23

Family

ID=37877026

Family Applications (1)

Application Number Title Priority Date Filing Date
DK087687A DK87687A (da) 1984-08-25 1987-02-20 1,6-naphthyridinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende dem

Country Status (11)

Country Link
US (1) US4751228A (fr)
EP (1) EP0234516B1 (fr)
JP (2) JPS61143382A (fr)
DD (1) DD236316A5 (fr)
DE (2) DE3431303A1 (fr)
DK (1) DK87687A (fr)
ES (1) ES2036533T3 (fr)
GR (1) GR3004468T3 (fr)
IE (1) IE59783B1 (fr)
PT (1) PT84339B (fr)
ZA (1) ZA856431B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906460C1 (fr) * 1989-03-01 1990-11-15 Goedecke Ag, 1000 Berlin, De
DE3906406C1 (fr) * 1989-03-01 1990-10-25 Goedecke Ag, 1000 Berlin, De
DE4202526A1 (de) * 1992-01-30 1993-08-05 Bayer Ag Neue 4-cinnolinyl- und 4-naphthyridinyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE102006026585A1 (de) * 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung
DE102006026583A1 (de) * 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung
DE102007009494A1 (de) * 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
CA2995949A1 (fr) * 2015-08-21 2017-03-02 Bayer Pharma Aktiengesellschaft Procede de preparation de (4s)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphtyridine-3-carboxamide et de recuperation de (4s)-4-(4-cyano-2-methoxyphenyl)- 5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphtyridine-3-carboxamide au moyen de methodes electrochimiques
PE20180554A1 (es) * 2015-08-21 2018-04-02 Bayer Pharma AG Procedimiento para la preparacion de (4s)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetilo-1,4-dihidro-1,6-naftiridina-3-carboxamida y su purificacion para su uso como principio activo farmaceutico

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5553291A (en) * 1978-10-17 1980-04-18 Nippon Kayaku Co Ltd Naphthylidine derivative and its preparation
EP0059291B1 (fr) * 1981-02-27 1985-03-27 American Home Products Corporation Agents antihypertensifs
AU532361B2 (en) * 1981-09-01 1983-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
US4415580A (en) * 1982-08-02 1983-11-15 Sterling Drug Inc. Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same
DE3327650A1 (de) * 1983-07-30 1985-02-14 Gödecke AG, 1000 Berlin 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von gefaesserkrankungen
IL75987A (en) * 1984-08-25 1991-07-18 Goedecke Ag Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US4751228A (en) 1988-06-14
PT84339A (pt) 1987-03-01
GR3004468T3 (fr) 1993-03-31
IE870436L (en) 1987-08-22
DE3431303A1 (de) 1986-02-27
EP0234516A1 (fr) 1987-09-02
PT84339B (pt) 1989-09-14
IE59783B1 (en) 1994-04-06
DK87687D0 (da) 1987-02-20
ZA856431B (en) 1986-04-30
JPS62198680A (ja) 1987-09-02
DD236316A5 (de) 1986-06-04
DE3431303C2 (fr) 1989-08-10
JPH0360834B2 (fr) 1991-09-17
DE3605743A1 (de) 1987-08-27
EP0234516B1 (fr) 1992-04-29
ES2036533T3 (es) 1993-06-01
JPS61143382A (ja) 1986-07-01

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