DK79991A - 1-substituerede 3-(1-oecyan eller carbamoylaa-1,1-diphenylmethyl)piperidin-forbindelser, fremgangsmaade til fremstilling deraf og anvendelse af forbindelserne til fremstilling af et laegemiddel til behandling af sygdomme forbundet med aendret motilitet og/eller tonus af glatmuskel samt tilsvarende i 1-stillingen usubstituerede forbindelser til anvendelse som mellemprodukter ved fremgangsmaaderne - Google Patents

1-substituerede 3-(1-oecyan eller carbamoylaa-1,1-diphenylmethyl)piperidin-forbindelser, fremgangsmaade til fremstilling deraf og anvendelse af forbindelserne til fremstilling af et laegemiddel til behandling af sygdomme forbundet med aendret motilitet og/eller tonus af glatmuskel samt tilsvarende i 1-stillingen usubstituerede forbindelser til anvendelse som mellemprodukter ved fremgangsmaaderne Download PDF

Info

Publication number
DK79991A
DK79991A DK079991A DK79991A DK79991A DK 79991 A DK79991 A DK 79991A DK 079991 A DK079991 A DK 079991A DK 79991 A DK79991 A DK 79991A DK 79991 A DK79991 A DK 79991A
Authority
DK
Denmark
Prior art keywords
alkyl
independently
substirely
oecyan
dypsyl
Prior art date
Application number
DK079991A
Other languages
English (en)
Other versions
DK79991D0 (da
DK175505B1 (da
Inventor
Peter Edward Cross
Alexander Roderick Mackenzie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK79991D0 publication Critical patent/DK79991D0/da
Publication of DK79991A publication Critical patent/DK79991A/da
Application granted granted Critical
Publication of DK175505B1 publication Critical patent/DK175505B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)
  • Filters That Use Time-Delay Elements (AREA)
  • Bending Of Plates, Rods, And Pipes (AREA)
  • Steroid Compounds (AREA)
DK199100799A 1988-11-01 1991-04-30 1-substituerede 3-(1-[cyan eller carbamoyl]-1,1-diphenylmethyl)piperidin-forbindelser og deres anvendelse til fremstilling af et lægemiddel til behandling af sygdomme forbundet med ændret motilitet og/eller tonus af glatmuskel....... DK175505B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8825505 1988-11-01
GB888825505A GB8825505D0 (en) 1988-11-01 1988-11-01 Therapeutic agents
EP8901300 1989-10-26
PCT/EP1989/001300 WO1990005133A1 (en) 1988-11-01 1989-10-26 Muscarinic receptor antagonists

Publications (3)

Publication Number Publication Date
DK79991D0 DK79991D0 (da) 1991-04-30
DK79991A true DK79991A (da) 1991-06-28
DK175505B1 DK175505B1 (da) 2004-11-15

Family

ID=10646093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199100799A DK175505B1 (da) 1988-11-01 1991-04-30 1-substituerede 3-(1-[cyan eller carbamoyl]-1,1-diphenylmethyl)piperidin-forbindelser og deres anvendelse til fremstilling af et lægemiddel til behandling af sygdomme forbundet med ændret motilitet og/eller tonus af glatmuskel.......

Country Status (13)

Country Link
US (1) US5422358A (da)
EP (2) EP0376358A1 (da)
JP (1) JPH0791268B2 (da)
AT (1) ATE153019T1 (da)
CA (1) CA1328454C (da)
DE (1) DE68928045T2 (da)
DK (1) DK175505B1 (da)
ES (1) ES2102353T3 (da)
FI (1) FI97468C (da)
GB (1) GB8825505D0 (da)
GR (1) GR3023974T3 (da)
PT (1) PT92158B (da)
WO (1) WO1990005133A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017931A (en) * 1994-03-01 2000-01-25 Fmc Corporation Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US5569664A (en) * 1995-02-16 1996-10-29 Fmc Corporation Insecticidal n-(substituted arylmethyl)-4-[bis(substituted phenyl) methyl]pi
US5639763A (en) * 1994-03-01 1997-06-17 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
AU7145996A (en) * 1995-10-13 1997-04-30 Banyu Pharmaceutical Co., Ltd. Substituted heteroaromatic derivatives
PE92198A1 (es) * 1996-08-01 1999-01-09 Banyu Pharma Co Ltd Derivados de 1,4-piperidina disustituida que contienen fluor
ES2203327B1 (es) * 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
US7368463B2 (en) * 2003-07-11 2008-05-06 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
WO2006097848A1 (en) * 2005-03-17 2006-09-21 Pfizer Inc. Hiv-1 virion maturation inhibitors, compositions and treatments using the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2139628A1 (en) 1971-05-28 1973-01-12 Lipha 5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity
US4032642A (en) * 1974-12-11 1977-06-28 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines
US4002766A (en) * 1974-12-26 1977-01-11 A. H. Robins Company, Incorporated Antiarrhythmia methods
US4242261A (en) * 1979-07-19 1980-12-30 A. H. Robins Company, Inc. Production of methylene-cycloamines
FR2531702A1 (fr) * 1982-08-16 1984-02-17 Synthelabo Derives de phenethyl-1a-phenylperidine-3-propanenitrile, leur preparation et leur application en therapeutique
FI842738A (fi) 1983-07-14 1985-01-15 Syntex Inc Aroylbenzofuran- och benzotiofenaettik- och propionsyror.
US4594343A (en) * 1984-10-19 1986-06-10 Shanklin Jr James R 1-[(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
IL76583A (en) 1984-10-19 1988-08-31 Robins Co Inc A H 1-(aminoalkyl)-alpha'alpha-diaryl pyrrolidinyl,piperidino and homopiperidino acetamides and acetonitriles and pharmaceutical compositions containing them
US4810713A (en) * 1985-12-20 1989-03-07 A. H. Robins Company, Incorporated Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment
EP0228893A3 (en) * 1985-12-20 1990-01-03 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl group in allergy treatment
IN163948B (da) * 1986-01-17 1988-12-10 Robins Co Inc A H
GB8824262D0 (en) * 1988-10-17 1988-11-23 Pfizer Ltd Therapeutic agents
GB8906166D0 (en) * 1989-03-17 1989-05-04 Pfizer Ltd Therapeutic agents
US7078474B2 (en) 2004-07-07 2006-07-18 E. I. Dupont De Nemours And Company Thermally curable coating compositions

Also Published As

Publication number Publication date
FI97468C (fi) 1996-12-27
DK79991D0 (da) 1991-04-30
GR3023974T3 (en) 1997-10-31
ES2102353T3 (es) 1997-08-01
DK175505B1 (da) 2004-11-15
JPH04500521A (ja) 1992-01-30
WO1990005133A1 (en) 1990-05-17
GB8825505D0 (en) 1988-12-07
DE68928045T2 (de) 1997-08-28
EP0376358A1 (en) 1990-07-04
FI97468B (fi) 1996-09-13
DE68928045D1 (de) 1997-06-19
US5422358A (en) 1995-06-06
EP0441852A1 (en) 1991-08-21
ATE153019T1 (de) 1997-05-15
EP0441852B1 (en) 1997-05-14
FI912085A0 (fi) 1991-04-30
PT92158B (pt) 1995-07-18
CA1328454C (en) 1994-04-12
JPH0791268B2 (ja) 1995-10-04
PT92158A (pt) 1990-05-31

Similar Documents

Publication Publication Date Title
WO1992005172A3 (en) Muscarinic receptor antagonists
FI922345A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 3-substituoitujen pyrrolidiinijohdannaisten valmistamiseksi
NO901241L (no) Fremgangsmaate ved fremstilling av pyrrolidinderivater.
DE3865504D1 (de) 1-phenyl-3-naphthalenyloxy-propanamine.
DK79991A (da) 1-substituerede 3-(1-oecyan eller carbamoylaa-1,1-diphenylmethyl)piperidin-forbindelser, fremgangsmaade til fremstilling deraf og anvendelse af forbindelserne til fremstilling af et laegemiddel til behandling af sygdomme forbundet med aendret motilitet og/eller tonus af glatmuskel samt tilsvarende i 1-stillingen usubstituerede forbindelser til anvendelse som mellemprodukter ved fremgangsmaaderne
PT96421A (pt) Processo para a preparacao de derivados de piperidina e de pirrolidina antagonistas de receptores muscarinicos
PT96419A (pt) Processo para a preparacao de derivados de piperidina e de pirrolidina antagonistas de receptores muscarinicos
IL91817A0 (en) Muscarinic receptor antagonists
CA2067759A1 (en) 3-phenyglutarimide derivatives as muscarinic receptor antagonists
NO20000750L (no) FremgangsmÕte for Õ redusere blodplatetall
NO951812L (no) Pyrrolderivater, deres fremstilling og anvendelse
FI922346A (fi) Muscarinreceptorantagonister.
NO951798L (no) Terapeutiske midler

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK