FR2139628A1 - 5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity - Google Patents

5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity

Info

Publication number
FR2139628A1
FR2139628A1 FR7119415A FR7119415A FR2139628A1 FR 2139628 A1 FR2139628 A1 FR 2139628A1 FR 7119415 A FR7119415 A FR 7119415A FR 7119415 A FR7119415 A FR 7119415A FR 2139628 A1 FR2139628 A1 FR 2139628A1
Authority
FR
France
Prior art keywords
indans
alkylene
alkyl
aryl piperazino
tranquillizing activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7119415A
Other languages
French (fr)
Other versions
FR2139628B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LIPHA SAS filed Critical LIPHA SAS
Priority to FR7119415A priority Critical patent/FR2139628A1/en
Publication of FR2139628A1 publication Critical patent/FR2139628A1/en
Application granted granted Critical
Publication of FR2139628B1 publication Critical patent/FR2139628B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Abstract

Cpds. of formula:- where n is 0 or 1; m is 0, 1, 2 or 3 provided that both m and n be not 0; Ar is pyridyl or opt. substd. phenyl, are prepd. by reaction of an aryl piperazine with an indan of formula:- or a reactive ester, or by other conventional processes.
FR7119415A 1971-05-28 1971-05-28 5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity Granted FR2139628A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7119415A FR2139628A1 (en) 1971-05-28 1971-05-28 5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7119415A FR2139628A1 (en) 1971-05-28 1971-05-28 5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity

Publications (2)

Publication Number Publication Date
FR2139628A1 true FR2139628A1 (en) 1973-01-12
FR2139628B1 FR2139628B1 (en) 1974-08-30

Family

ID=9077775

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7119415A Granted FR2139628A1 (en) 1971-05-28 1971-05-28 5-(4-aryl piperazino-alkyl and alkylene) indans - with tranquillizing activity

Country Status (1)

Country Link
FR (1) FR2139628A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088787A (en) * 1974-02-07 1978-05-09 Societe Hexachimie Indane ethanols
US4686220A (en) * 1985-12-19 1987-08-11 American Cyanamid Company Substituted 2-[b-substituted-amino)-ethylamino]-1,4-naphthalenediones for treating asthma, allergic diseases and inflammation in warm-blooded animals
US4792553A (en) * 1986-02-04 1988-12-20 Terumo Kabushiki Kaisha Diene derivatives and vasodilators containing the same
US4876349A (en) * 1986-07-15 1989-10-24 Hoffmann-La Roche Inc. Tetrahydronaphthalene and indane derivatives
EP0376358A1 (en) 1988-11-01 1990-07-04 Pfizer Inc. Muscarinic receptor antagonists
CN109384707A (en) * 2018-10-16 2019-02-26 华东理工大学 Benzo rouge (fat) ring derivatives and application thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088787A (en) * 1974-02-07 1978-05-09 Societe Hexachimie Indane ethanols
US4686220A (en) * 1985-12-19 1987-08-11 American Cyanamid Company Substituted 2-[b-substituted-amino)-ethylamino]-1,4-naphthalenediones for treating asthma, allergic diseases and inflammation in warm-blooded animals
AU593310B2 (en) * 1985-12-19 1990-02-08 American Cyanamid Company Substituted piperazine-1,4-naphthalenediones
US4792553A (en) * 1986-02-04 1988-12-20 Terumo Kabushiki Kaisha Diene derivatives and vasodilators containing the same
US4876349A (en) * 1986-07-15 1989-10-24 Hoffmann-La Roche Inc. Tetrahydronaphthalene and indane derivatives
EP0376358A1 (en) 1988-11-01 1990-07-04 Pfizer Inc. Muscarinic receptor antagonists
CN109384707A (en) * 2018-10-16 2019-02-26 华东理工大学 Benzo rouge (fat) ring derivatives and application thereof
CN109384707B (en) * 2018-10-16 2021-12-17 华东理工大学 Benzo (aliphatic) cyclo derivative and use thereof

Also Published As

Publication number Publication date
FR2139628B1 (en) 1974-08-30

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Legal Events

Date Code Title Description
ST Notification of lapse