FR2254315A1 - 1-Alpha-naphthoxy-3-amino-prop-2-yl nicotinates - with hypolipaemic antiarrhythmic and cardiovascular protective activity - Google Patents

1-Alpha-naphthoxy-3-amino-prop-2-yl nicotinates - with hypolipaemic antiarrhythmic and cardiovascular protective activity

Info

Publication number
FR2254315A1
FR2254315A1 FR7344982A FR7344982A FR2254315A1 FR 2254315 A1 FR2254315 A1 FR 2254315A1 FR 7344982 A FR7344982 A FR 7344982A FR 7344982 A FR7344982 A FR 7344982A FR 2254315 A1 FR2254315 A1 FR 2254315A1
Authority
FR
France
Prior art keywords
hypolipaemic
nicotinates
naphthoxy
antiarrhythmic
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7344982A
Other languages
French (fr)
Other versions
FR2254315B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Produits Chimiques Ugine Kuhlmann
Ugine Kuhlmann SA
Original Assignee
Produits Chimiques Ugine Kuhlmann
Ugine Kuhlmann SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Produits Chimiques Ugine Kuhlmann, Ugine Kuhlmann SA filed Critical Produits Chimiques Ugine Kuhlmann
Priority to FR7344982A priority Critical patent/FR2254315A1/en
Publication of FR2254315A1 publication Critical patent/FR2254315A1/en
Application granted granted Critical
Publication of FR2254315B1 publication Critical patent/FR2254315B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

1-alpha-Naphthoxy-3-aminoprop-2-yl nicotinates of formula (I) (where R, R' are alkyl; or R + R' and the attached N-atom are opt. satd. heterocyclic ring with extra opt. hetero-atom) are hypolipaemic, antiarrhythmic and cardiovascular protective agents. They are prepd. by esterification of the propan-2-ols with nicotinyl chloride.
FR7344982A 1973-12-17 1973-12-17 1-Alpha-naphthoxy-3-amino-prop-2-yl nicotinates - with hypolipaemic antiarrhythmic and cardiovascular protective activity Granted FR2254315A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7344982A FR2254315A1 (en) 1973-12-17 1973-12-17 1-Alpha-naphthoxy-3-amino-prop-2-yl nicotinates - with hypolipaemic antiarrhythmic and cardiovascular protective activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7344982A FR2254315A1 (en) 1973-12-17 1973-12-17 1-Alpha-naphthoxy-3-amino-prop-2-yl nicotinates - with hypolipaemic antiarrhythmic and cardiovascular protective activity

Publications (2)

Publication Number Publication Date
FR2254315A1 true FR2254315A1 (en) 1975-07-11
FR2254315B1 FR2254315B1 (en) 1977-04-22

Family

ID=9129293

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7344982A Granted FR2254315A1 (en) 1973-12-17 1973-12-17 1-Alpha-naphthoxy-3-amino-prop-2-yl nicotinates - with hypolipaemic antiarrhythmic and cardiovascular protective activity

Country Status (1)

Country Link
FR (1) FR2254315A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0472800A1 (en) * 1988-12-28 1992-03-04 Peter Dr. Sandmeier Metoprololnicotinic acid ester, method of preparation and pharmaceutical use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0472800A1 (en) * 1988-12-28 1992-03-04 Peter Dr. Sandmeier Metoprololnicotinic acid ester, method of preparation and pharmaceutical use

Also Published As

Publication number Publication date
FR2254315B1 (en) 1977-04-22

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Legal Events

Date Code Title Description
TP Transmission of property
CD Change of name or company name
TP Transmission of property
ST Notification of lapse