DK75484A - 4,5-dihydro-6-((substitueret)-1h-imidazol-4-yl- eller -5-yl)-3(2h)-pyridazinoner og 6-((substitueret)-1h-imidazol-4-yl eller -5-yl)-3(2h)-pyridazinoner og syreadditionssalte deraf, fremgangsmaade til deres fremstilling samt deres anvendelse - Google Patents
4,5-dihydro-6-((substitueret)-1h-imidazol-4-yl- eller -5-yl)-3(2h)-pyridazinoner og 6-((substitueret)-1h-imidazol-4-yl eller -5-yl)-3(2h)-pyridazinoner og syreadditionssalte deraf, fremgangsmaade til deres fremstilling samt deres anvendelse Download PDFInfo
- Publication number
- DK75484A DK75484A DK75484A DK75484A DK75484A DK 75484 A DK75484 A DK 75484A DK 75484 A DK75484 A DK 75484A DK 75484 A DK75484 A DK 75484A DK 75484 A DK75484 A DK 75484A
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- pyridazinones
- imidazol
- dihydro
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/477,697 US4521416A (en) | 1983-03-22 | 1983-03-22 | 4,5-Dihydro-6-[(substituted)-1H-imidazol-4-yl or 5-yl]-3(2H)-pyridazinones and 6-[(substituted)-1H-imidazol-4-yl or 5-yl]-3(2H)-pyridazinones |
Publications (2)
Publication Number | Publication Date |
---|---|
DK75484D0 DK75484D0 (da) | 1984-02-17 |
DK75484A true DK75484A (da) | 1984-09-23 |
Family
ID=23896976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK75484A DK75484A (da) | 1983-03-22 | 1984-02-17 | 4,5-dihydro-6-((substitueret)-1h-imidazol-4-yl- eller -5-yl)-3(2h)-pyridazinoner og 6-((substitueret)-1h-imidazol-4-yl eller -5-yl)-3(2h)-pyridazinoner og syreadditionssalte deraf, fremgangsmaade til deres fremstilling samt deres anvendelse |
Country Status (10)
Country | Link |
---|---|
US (1) | US4521416A (ja) |
EP (1) | EP0125749B1 (ja) |
JP (1) | JPS59176279A (ja) |
AT (1) | ATE37717T1 (ja) |
AU (1) | AU556250B2 (ja) |
CA (1) | CA1210765A (ja) |
DE (1) | DE3474451D1 (ja) |
DK (1) | DK75484A (ja) |
ES (1) | ES530809A0 (ja) |
GR (1) | GR81887B (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3321012A1 (de) * | 1983-06-10 | 1984-12-13 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 4,5-dihydro-6-(thien-2-yl)-3(2h)-pyridazinone und 6-(thien-2-yl)-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung |
US4666902A (en) * | 1983-06-20 | 1987-05-19 | Cassella Aktiengesellschaft | Tetrahydropyridazinone derivatives, processes for their preparation and their use |
GB8323553D0 (en) * | 1983-09-02 | 1983-10-05 | Smith Kline French Lab | Pharmaceutical compositions |
JPS60197672A (ja) * | 1984-03-16 | 1985-10-07 | Mitsubishi Chem Ind Ltd | ビリダジノン誘導体またはその塩類 |
JPS60126282A (ja) * | 1983-12-14 | 1985-07-05 | Mitsubishi Chem Ind Ltd | ピリダジノン誘導体又はその塩類 |
US4631279A (en) * | 1984-10-15 | 1986-12-23 | Eli Lilly And Company | 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents |
US4826835A (en) * | 1985-10-23 | 1989-05-02 | Rorer Pharmaceutical Corporation | Pyridyl-pyridazinone and pyridyl-pyrazolinone compounds and their use in the treatment of congestive heart failure |
US4783463A (en) * | 1985-10-23 | 1988-11-08 | Rorer Pharmaceutical Corporation | Pyridyl-pyridazinone and pyridyl-pyrazolinone compounds and their use in the treatment of congestive heart failure |
HU195645B (en) * | 1985-10-30 | 1988-06-28 | Gyogyszerkutato Intezet | Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same |
US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
US5011840A (en) * | 1986-11-24 | 1991-04-30 | Pfizer Inc. | Imidazolidinedione derivatives in diabetes treatment |
DE3734083A1 (de) * | 1987-10-08 | 1989-04-20 | Heumann Pharma Gmbh & Co | Benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
WO1989008108A1 (en) * | 1988-02-23 | 1989-09-08 | Rorer International (Overseas) Inc. | Pyridyl-pyridazinone and pyridyl-pyrazolinone compounds and their use in the treatment of congestive heart failure |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8101067A1 (es) * | 1978-08-25 | 1980-12-01 | Thomae Gmbh Dr K | Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona |
DE2935359A1 (de) * | 1979-09-01 | 1981-03-26 | Basf Ag, 67063 Ludwigshafen | 6-imidazolyl-3-hydrazino-pyridazine |
US4353905A (en) * | 1981-09-17 | 1982-10-12 | Warner-Lambert Company | Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones |
-
1983
- 1983-03-22 US US06/477,697 patent/US4521416A/en not_active Expired - Fee Related
-
1984
- 1984-02-15 CA CA000447538A patent/CA1210765A/en not_active Expired
- 1984-02-17 DK DK75484A patent/DK75484A/da not_active Application Discontinuation
- 1984-02-22 AU AU24821/84A patent/AU556250B2/en not_active Ceased
- 1984-02-23 EP EP84301160A patent/EP0125749B1/en not_active Expired
- 1984-02-23 AT AT84301160T patent/ATE37717T1/de not_active IP Right Cessation
- 1984-02-23 DE DE8484301160T patent/DE3474451D1/de not_active Expired
- 1984-03-16 GR GR74130A patent/GR81887B/el unknown
- 1984-03-21 ES ES530809A patent/ES530809A0/es active Granted
- 1984-03-21 JP JP59052436A patent/JPS59176279A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES8600277A1 (es) | 1985-06-16 |
EP0125749A2 (en) | 1984-11-21 |
EP0125749A3 (en) | 1986-06-11 |
GR81887B (ja) | 1984-12-12 |
ATE37717T1 (de) | 1988-10-15 |
DK75484D0 (da) | 1984-02-17 |
AU2482184A (en) | 1984-09-27 |
DE3474451D1 (de) | 1988-11-10 |
JPS59176279A (ja) | 1984-10-05 |
CA1210765A (en) | 1986-09-02 |
EP0125749B1 (en) | 1988-10-05 |
AU556250B2 (en) | 1986-10-30 |
ES530809A0 (es) | 1985-06-16 |
US4521416A (en) | 1985-06-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |