DK661789A - Di- og tripeptidderivater samt fremgangsmaade til fremstilling deraf - Google Patents

Di- og tripeptidderivater samt fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK661789A
DK661789A DK661789A DK661789A DK661789A DK 661789 A DK661789 A DK 661789A DK 661789 A DK661789 A DK 661789A DK 661789 A DK661789 A DK 661789A DK 661789 A DK661789 A DK 661789A
Authority
DK
Denmark
Prior art keywords
diet
procedures
preparing
tripeptide derivatives
tripeptide
Prior art date
Application number
DK661789A
Other languages
Danish (da)
English (en)
Other versions
DK661789D0 (da
Inventor
Jay Donald Albright
Fuk-Wah Sum
Charles Frederick Howell
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK661789D0 publication Critical patent/DK661789D0/da
Publication of DK661789A publication Critical patent/DK661789A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK661789A 1988-12-27 1989-12-22 Di- og tripeptidderivater samt fremgangsmaade til fremstilling deraf DK661789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29007988A 1988-12-27 1988-12-27

Publications (2)

Publication Number Publication Date
DK661789D0 DK661789D0 (da) 1989-12-22
DK661789A true DK661789A (da) 1990-06-28

Family

ID=23114455

Family Applications (1)

Application Number Title Priority Date Filing Date
DK661789A DK661789A (da) 1988-12-27 1989-12-22 Di- og tripeptidderivater samt fremgangsmaade til fremstilling deraf

Country Status (11)

Country Link
EP (1) EP0376012A3 (fi)
JP (1) JPH02215799A (fi)
KR (1) KR900009688A (fi)
AU (1) AU4721489A (fi)
CA (1) CA2006374A1 (fi)
DK (1) DK661789A (fi)
FI (1) FI896238A0 (fi)
IL (1) IL92643A0 (fi)
NO (1) NO895230L (fi)
PT (1) PT92732A (fi)
ZA (1) ZA899924B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0427939A3 (en) * 1989-10-11 1991-11-06 American Cyanamid Company Renin inhibitors
JP2578044B2 (ja) * 1992-03-14 1997-02-05 呉羽化学工業株式会社 フェニルアラニン−グリシン誘導体、その製造方法、及びその誘導体を含有する抗腫瘍剤
US6159938A (en) * 1994-11-21 2000-12-12 Cortech, Inc. Serine protease inhibitors comprising α-keto heterocycles
US5618792A (en) * 1994-11-21 1997-04-08 Cortech, Inc. Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
TW200404789A (en) 1999-03-15 2004-04-01 Axys Pharm Inc Novel compounds and compositions as protease inhibitors
US7030116B2 (en) 2000-12-22 2006-04-18 Aventis Pharmaceuticals Inc. Compounds and compositions as cathepsin inhibitors
MXPA03005601A (es) 2000-12-22 2004-12-02 Axys Pharm Inc Nuevos compuestos y composiciones como inhibidores de catepsina.
CN1324008C (zh) 2001-09-14 2007-07-04 安万特药物公司 作为组织蛋白酶抑制剂的新化合物和组合物
WO2003042197A1 (en) 2001-11-14 2003-05-22 Aventis Pharmaceuticals Inc. Oligopeptides and compositions containing them as cathepsin s inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0212550A3 (en) * 1985-08-14 1989-05-10 G.D. Searle & Co. Substituted dipeptide amides
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors

Also Published As

Publication number Publication date
EP0376012A3 (en) 1992-05-06
PT92732A (pt) 1990-06-29
FI896238A0 (fi) 1989-12-22
AU4721489A (en) 1990-07-05
NO895230L (no) 1990-06-28
EP0376012A2 (en) 1990-07-04
JPH02215799A (ja) 1990-08-28
DK661789D0 (da) 1989-12-22
CA2006374A1 (en) 1990-06-27
IL92643A0 (en) 1990-08-31
ZA899924B (en) 1990-09-26
KR900009688A (ko) 1990-07-05
NO895230D0 (no) 1989-12-22

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment