ZA899924B - Renin inhibitors - Google Patents
Renin inhibitorsInfo
- Publication number
- ZA899924B ZA899924B ZA899924A ZA899924A ZA899924B ZA 899924 B ZA899924 B ZA 899924B ZA 899924 A ZA899924 A ZA 899924A ZA 899924 A ZA899924 A ZA 899924A ZA 899924 B ZA899924 B ZA 899924B
- Authority
- ZA
- South Africa
- Prior art keywords
- renin inhibitors
- renin
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29007988A | 1988-12-27 | 1988-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA899924B true ZA899924B (en) | 1990-09-26 |
Family
ID=23114455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA899924A ZA899924B (en) | 1988-12-27 | 1989-12-27 | Renin inhibitors |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0376012A3 (fi) |
JP (1) | JPH02215799A (fi) |
KR (1) | KR900009688A (fi) |
AU (1) | AU4721489A (fi) |
CA (1) | CA2006374A1 (fi) |
DK (1) | DK661789A (fi) |
FI (1) | FI896238A0 (fi) |
IL (1) | IL92643A0 (fi) |
NO (1) | NO895230L (fi) |
PT (1) | PT92732A (fi) |
ZA (1) | ZA899924B (fi) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0427939A3 (en) * | 1989-10-11 | 1991-11-06 | American Cyanamid Company | Renin inhibitors |
JP2578044B2 (ja) * | 1992-03-14 | 1997-02-05 | 呉羽化学工業株式会社 | フェニルアラニン−グリシン誘導体、その製造方法、及びその誘導体を含有する抗腫瘍剤 |
US6159938A (en) * | 1994-11-21 | 2000-12-12 | Cortech, Inc. | Serine protease inhibitors comprising α-keto heterocycles |
US5618792A (en) * | 1994-11-21 | 1997-04-08 | Cortech, Inc. | Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase |
TW200404789A (en) | 1999-03-15 | 2004-04-01 | Axys Pharm Inc | Novel compounds and compositions as protease inhibitors |
US7064123B1 (en) | 2000-12-22 | 2006-06-20 | Aventis Pharmaceuticals Inc. | Compounds and compositions as cathepsin inhibitors |
US7030116B2 (en) | 2000-12-22 | 2006-04-18 | Aventis Pharmaceuticals Inc. | Compounds and compositions as cathepsin inhibitors |
WO2003024924A1 (en) | 2001-09-14 | 2003-03-27 | Aventis Pharmaceuticals Inc. | Novel compounds and compositions as cathepsin inhibitors |
HUP0401906A3 (en) | 2001-11-14 | 2008-07-28 | Aventis Pharma Inc | Novel cathepsin s inhibitors, process for their preparation and pharmaceutical compositions containing them |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU589665B2 (en) * | 1985-08-14 | 1989-10-19 | G.D. Searle & Co. | Substituted dipeptide amides |
ZA87563B (en) * | 1986-02-03 | 1987-09-30 | Squibb & Sons Inc | N-heterocyclic alcohol renin inhibitors |
-
1989
- 1989-12-07 EP EP19890122560 patent/EP0376012A3/en not_active Withdrawn
- 1989-12-12 IL IL92643A patent/IL92643A0/xx unknown
- 1989-12-21 CA CA002006374A patent/CA2006374A1/en not_active Abandoned
- 1989-12-22 AU AU47214/89A patent/AU4721489A/en not_active Abandoned
- 1989-12-22 FI FI896238A patent/FI896238A0/fi not_active Application Discontinuation
- 1989-12-22 DK DK661789A patent/DK661789A/da not_active Application Discontinuation
- 1989-12-22 NO NO89895230A patent/NO895230L/no unknown
- 1989-12-26 KR KR1019890019531A patent/KR900009688A/ko not_active Application Discontinuation
- 1989-12-27 PT PT92732A patent/PT92732A/pt not_active Application Discontinuation
- 1989-12-27 JP JP1339882A patent/JPH02215799A/ja active Pending
- 1989-12-27 ZA ZA899924A patent/ZA899924B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL92643A0 (en) | 1990-08-31 |
JPH02215799A (ja) | 1990-08-28 |
KR900009688A (ko) | 1990-07-05 |
PT92732A (pt) | 1990-06-29 |
DK661789A (da) | 1990-06-28 |
EP0376012A2 (en) | 1990-07-04 |
FI896238A0 (fi) | 1989-12-22 |
EP0376012A3 (en) | 1992-05-06 |
DK661789D0 (da) | 1989-12-22 |
AU4721489A (en) | 1990-07-05 |
NO895230L (no) | 1990-06-28 |
NO895230D0 (no) | 1989-12-22 |
CA2006374A1 (en) | 1990-06-27 |
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