DK653088D0 - Anti-inflammatoriske derivater af di-tert-butylphenolforbindelser og farmaceutisk middel omfattende samme - Google Patents

Anti-inflammatoriske derivater af di-tert-butylphenolforbindelser og farmaceutisk middel omfattende samme

Info

Publication number
DK653088D0
DK653088D0 DK653088A DK653088A DK653088D0 DK 653088 D0 DK653088 D0 DK 653088D0 DK 653088 A DK653088 A DK 653088A DK 653088 A DK653088 A DK 653088A DK 653088 D0 DK653088 D0 DK 653088D0
Authority
DK
Denmark
Prior art keywords
compounds
butylphenolic
tert
pharmaceutical composition
inflammatory derivatives
Prior art date
Application number
DK653088A
Other languages
English (en)
Other versions
DK653088A (da
DK173367B1 (da
Inventor
Roy Lee Martin Dobson
Maurice Edward Loomans
Randall Stryker Matthews
Joseph Arthur Miller
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of DK653088D0 publication Critical patent/DK653088D0/da
Publication of DK653088A publication Critical patent/DK653088A/da
Application granted granted Critical
Publication of DK173367B1 publication Critical patent/DK173367B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
DK198806530A 1987-11-23 1988-11-23 Anti-inflammatoriske derivater af di-tert-butylphenol, farmaceutisk præparat omfattende samme samt anvendelse af et sådant DK173367B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/123,756 US4849428A (en) 1987-11-23 1987-11-23 Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use
US12375687 1987-11-23

Publications (3)

Publication Number Publication Date
DK653088D0 true DK653088D0 (da) 1988-11-23
DK653088A DK653088A (da) 1989-05-24
DK173367B1 DK173367B1 (da) 2000-08-21

Family

ID=22410695

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198806530A DK173367B1 (da) 1987-11-23 1988-11-23 Anti-inflammatoriske derivater af di-tert-butylphenol, farmaceutisk præparat omfattende samme samt anvendelse af et sådant

Country Status (14)

Country Link
US (1) US4849428A (da)
EP (1) EP0322004B1 (da)
JP (1) JP2602931B2 (da)
KR (1) KR970011460B1 (da)
AT (1) ATE71623T1 (da)
AU (1) AU621571B2 (da)
CA (1) CA1308110C (da)
DE (1) DE3867827D1 (da)
DK (1) DK173367B1 (da)
IE (1) IE61197B1 (da)
IL (1) IL88365A (da)
NZ (1) NZ227039A (da)
PH (1) PH25855A (da)
ZA (1) ZA888727B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4982006A (en) * 1987-12-18 1991-01-01 Norwich Eaton Pharmaceuticals, Inc. Process for the preparation of certain substituted aromatic compounds
GB8827850D0 (en) * 1988-11-29 1988-12-29 Shell Int Research Biocidal compounds
US5189066A (en) * 1989-11-22 1993-02-23 The Procter & Gamble Company Pharmaceutical compositions of tebufelone
US5126487A (en) * 1991-03-26 1992-06-30 The Procter & Gamble Company Process for the preparation of 2-alkyl-4-acyl-6-tert-butylphenol compounds
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
US5674891A (en) * 1994-07-27 1997-10-07 The Procter & Gamble Company Dihydrobenzothiophene compounds useful as anti-inflammatory agents
JPH10506615A (ja) * 1994-07-27 1998-06-30 ザ、プロクター、エンド、ギャンブル、カンパニー 抗炎症剤として有用なジヒドロベンゾフラン及び関連化合物
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
US5750543A (en) * 1996-02-01 1998-05-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5618835A (en) * 1996-02-01 1997-04-08 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5686471A (en) * 1996-02-01 1997-11-11 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684041A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
FR2744452B1 (fr) * 1996-02-06 1998-03-06 Cird Galderma Composes biaryles heterocycliques, compositions pharmaceutiques et cosmetiques les contenant et utilisations
WO2004064781A2 (en) * 2003-01-14 2004-08-05 Adam Heller Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1922815A1 (de) * 1969-05-05 1970-11-12 Merck Anlagen Gmbh Phenolaether und Phenolester als Stabilisatoren
US3829446A (en) * 1970-10-15 1974-08-13 Pfizer Oxobenzofuran intermediates
US3862133A (en) * 1973-04-30 1975-01-21 Goodrich Co B F Gamma-lactones of o-hydroxyphenylacetic acids
US4013690A (en) * 1974-02-05 1977-03-22 Sandoz Ltd. Organic compounds
DK137274B (da) * 1975-03-12 1978-02-13 Sandoz Ag Analogifremgangsmåde til fremstilling af 2,3-dihydrobenzofuranon-2-derivater.
US4130666A (en) * 1977-05-16 1978-12-19 Riker Laboratories, Inc. Anti-inflammatory method
DE2803544A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue benzofuran- und benzoxepinderivate
GB2042562B (en) * 1979-02-05 1983-05-11 Sandoz Ltd Stabilising polymers
DE2931672A1 (de) * 1979-08-04 1981-02-26 Basf Ag Substituierte 2,3-dihydrobenzofurylmethylester, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
US4440784A (en) * 1981-02-05 1984-04-03 Kanegafuchi Chemical Industry Company, Ltd. Anti-inflammatory, analgesic, and antipyretic pharmaceutical composition
US4431656A (en) * 1981-02-05 1984-02-14 Kanegafuchi Chemical Industry Company Limited 3,5-di-Tert-butylstyrene derivatives, salts thereof, and pharmaceutical compositions containing the same as an active ingredient
US4514415A (en) * 1981-10-28 1985-04-30 Ciba Geigy Corporation Benzofuran-2(3H)-ones used as anti-inflammatory agents
JPH0623194B2 (ja) * 1985-03-23 1994-03-30 鐘淵化学工業株式会社 新規ラクタム誘導体及び抗炎症剤
US4711903A (en) * 1986-01-31 1987-12-08 G. D. Searle & Co. Phenolic thioethers as inhibitors of 5-lipoxygenase
US4708966A (en) * 1986-06-27 1987-11-24 The Procter & Gamble Company Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation
US4911754A (en) * 1987-07-16 1990-03-27 American Cyanamid Company Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds
JPH0654315A (ja) * 1992-07-31 1994-02-25 Canon Inc 動画像符号化方法及び装置

Also Published As

Publication number Publication date
NZ227039A (en) 1990-10-26
DK653088A (da) 1989-05-24
AU2577188A (en) 1989-05-25
DE3867827D1 (de) 1992-02-27
JP2602931B2 (ja) 1997-04-23
CA1308110C (en) 1992-09-29
AU621571B2 (en) 1992-03-19
US4849428A (en) 1989-07-18
EP0322004A1 (en) 1989-06-28
KR970011460B1 (ko) 1997-07-11
IE883491L (en) 1989-05-23
JPH01250372A (ja) 1989-10-05
IL88365A0 (en) 1989-06-30
ATE71623T1 (de) 1992-02-15
EP0322004B1 (en) 1992-01-15
IE61197B1 (en) 1994-10-19
IL88365A (en) 1994-02-27
KR890008123A (ko) 1989-07-08
DK173367B1 (da) 2000-08-21
ZA888727B (en) 1989-08-30
PH25855A (en) 1991-12-02

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