DK641489D0 - Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n epimerase (racemase) aktivitet - Google Patents

Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n epimerase (racemase) aktivitet

Info

Publication number
DK641489D0
DK641489D0 DK641489A DK641489A DK641489D0 DK 641489 D0 DK641489 D0 DK 641489D0 DK 641489 A DK641489 A DK 641489A DK 641489 A DK641489 A DK 641489A DK 641489 D0 DK641489 D0 DK 641489D0
Authority
DK
Denmark
Prior art keywords
racemase
epimerase
activity
expression vectors
isopenicillin
Prior art date
Application number
DK641489A
Other languages
English (en)
Other versions
DK641489A (da
Inventor
Steven Kovacevic
James Robert Miller
Paul Luther Skatrud
Matthew Barry Tobin
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK641489D0 publication Critical patent/DK641489D0/da
Publication of DK641489A publication Critical patent/DK641489A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK641489A 1988-12-22 1989-12-18 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n epimerase (racemase) aktivitet DK641489A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28876088A 1988-12-22 1988-12-22

Publications (2)

Publication Number Publication Date
DK641489D0 true DK641489D0 (da) 1989-12-18
DK641489A DK641489A (da) 1990-06-23

Family

ID=23108528

Family Applications (1)

Application Number Title Priority Date Filing Date
DK641489A DK641489A (da) 1988-12-22 1989-12-18 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n epimerase (racemase) aktivitet

Country Status (12)

Country Link
EP (1) EP0377295B1 (da)
JP (1) JPH02227082A (da)
AT (1) ATE118042T1 (da)
AU (1) AU622253B2 (da)
CA (1) CA2005649A1 (da)
DE (1) DE68920987T2 (da)
DK (1) DK641489A (da)
ES (1) ES2067556T3 (da)
GR (1) GR3015473T3 (da)
HU (1) HU208713B (da)
IE (1) IE894168L (da)
IL (1) IL92740A0 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94651A0 (en) * 1989-06-12 1991-04-15 Univ Oklahoma State Purified enzyme and process therefor
CA2034735A1 (en) * 1990-01-26 1991-07-27 Barbara J. Weigel Recombinant dna expression and dna compounds that encode isopenicillin n epimerase activity
US5882883A (en) * 1994-09-28 1999-03-16 Novo Nordisk A/S Process for the production of secondary metabolites
FR2744455B1 (fr) * 1996-02-02 1998-04-24 Sanofi Sa Nouvelles sequences d'acides nucleiques de la famille des facteurs suppresseurs de tumeurs, produits d'expression correspondants et leurs applications
US7030227B1 (en) 1997-10-15 2006-04-18 President & Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
US7294459B1 (en) 1997-10-15 2007-11-13 President And Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
EP2376619A4 (en) 2008-12-15 2012-07-04 Greenlight Biosciences Inc METHODS FOR CONTROLLING FLOWS IN METABOLIC PATHWAYS
DK2566953T3 (da) 2010-05-07 2019-04-15 Greenlight Biosciences Inc Fremgangsmåder til styring af strømmen ad metaboliske veje ved hjælp af enzymrelokering
KR101988063B1 (ko) 2010-08-31 2019-09-30 그린라이트 바이오사이언시스, 아이엔씨. 프로테아제 조작을 통한 대사 경로에서 유동의 제어 방법
KR20150010932A (ko) 2011-09-09 2015-01-29 그린라이트 바이오사이언시스, 아이엔씨. 카바페넴의 무세포 제조법
CN105658807A (zh) 2013-08-05 2016-06-08 绿光生物科技股份有限公司 具有蛋白酶切割位点的工程化蛋白
JP6843065B2 (ja) 2015-03-30 2021-03-17 グリーンライト バイオサイエンシーズ インコーポレーテッドＧｒｅｅｎｌｉｇｈｔ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． リボ核酸の無細胞生産
US10954541B2 (en) 2016-04-06 2021-03-23 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
SG11202003192UA (en) 2017-10-11 2020-05-28 Greenlight Biosciences Inc Methods and compositions for nucleoside triphosphate and ribonucleic acid production

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195383B (en) * 1984-11-21 1988-04-28 Medicor Muevek Device for adjusting parameters of exposure of an x-ray equipment

Also Published As

Publication number Publication date
AU4709889A (en) 1990-06-28
ES2067556T3 (es) 1995-04-01
HU208713B (en) 1993-12-28
HUT53149A (en) 1990-09-28
JPH02227082A (ja) 1990-09-10
DE68920987D1 (de) 1995-03-16
IE894168L (en) 1990-06-22
DE68920987T2 (de) 1995-06-22
GR3015473T3 (en) 1995-06-30
EP0377295B1 (en) 1995-02-01
HU896734D0 (en) 1990-02-28
AU622253B2 (en) 1992-04-02
IL92740A0 (en) 1990-09-17
DK641489A (da) 1990-06-23
CA2005649A1 (en) 1990-06-22
EP0377295A1 (en) 1990-07-11
ATE118042T1 (de) 1995-02-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment