DK618886A - 6,7,8,9-tetrahydro-10-methylpyrido-(1,2-a)-indol-9-aminer og derivater deraf, samt deres fremstilling og anvendelse - Google Patents

6,7,8,9-tetrahydro-10-methylpyrido-(1,2-a)-indol-9-aminer og derivater deraf, samt deres fremstilling og anvendelse

Info

Publication number
DK618886A
DK618886A DK618886A DK618886A DK618886A DK 618886 A DK618886 A DK 618886A DK 618886 A DK618886 A DK 618886A DK 618886 A DK618886 A DK 618886A DK 618886 A DK618886 A DK 618886A
Authority
DK
Denmark
Prior art keywords
methylpyrido
indol
tetrahydro
amines
derivatives
Prior art date
Application number
DK618886A
Other languages
Danish (da)
English (en)
Other versions
DK618886D0 (da
Inventor
Ivo Ladislav Jirkovsky
Gary Alan King
Reinhardt Bernhard Baudy
Victor John Denoble
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of DK618886D0 publication Critical patent/DK618886D0/da
Publication of DK618886A publication Critical patent/DK618886A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK618886A 1985-12-20 1986-12-19 6,7,8,9-tetrahydro-10-methylpyrido-(1,2-a)-indol-9-aminer og derivater deraf, samt deres fremstilling og anvendelse DK618886A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/811,551 US4624954A (en) 1985-12-20 1985-12-20 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments

Publications (2)

Publication Number Publication Date
DK618886D0 DK618886D0 (da) 1986-12-19
DK618886A true DK618886A (da) 1987-06-21

Family

ID=25206862

Family Applications (1)

Application Number Title Priority Date Filing Date
DK618886A DK618886A (da) 1985-12-20 1986-12-19 6,7,8,9-tetrahydro-10-methylpyrido-(1,2-a)-indol-9-aminer og derivater deraf, samt deres fremstilling og anvendelse

Country Status (11)

Country Link
US (1) US4624954A (fi)
EP (1) EP0228825A1 (fi)
JP (1) JPS62148487A (fi)
KR (1) KR870006048A (fi)
AU (1) AU6556286A (fi)
DK (1) DK618886A (fi)
FI (1) FI864891A (fi)
HU (1) HUT45249A (fi)
IL (1) IL80658A0 (fi)
PT (1) PT83801B (fi)
ZA (1) ZA868752B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8416724D0 (en) * 1984-06-30 1984-08-01 Sorbio Sa Lab Active compounds
DE3677101D1 (de) * 1985-06-28 1991-02-28 Beecham Wuelfing Gmbh & Co Kg Tetrahydropyrido-(1,2-a)-indolderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
EP0252643A1 (en) * 1986-07-01 1988-01-13 BEECHAM - WUELFING GmbH & Co. KG Pyrido[1,2-a]indole derivatives, process for their preparation and pharmaceutical compounds containing them
US4778812A (en) * 1987-06-12 1988-10-18 American Home Products Corporation 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives thereof
TW200800959A (en) * 2005-06-10 2008-01-01 Wyeth Corp Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor
WO2006138549A1 (en) * 2005-06-17 2006-12-28 Wyeth Tricyclic compounds useful as serotonin inhibitors and 5-ht1a agonists and antagonists
TW200808741A (en) * 2006-06-09 2008-02-16 Wyeth Corp 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts
TW200811144A (en) * 2006-06-09 2008-03-01 Wyeth Corp Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline
TW200808740A (en) * 2006-06-09 2008-02-16 Wyeth Corp Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof
US20080262228A1 (en) * 2006-11-28 2008-10-23 Wyeth Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof
TW200901974A (en) 2007-01-16 2009-01-16 Wyeth Corp Compounds, compositions, and methods of making and using them

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035370A (en) * 1971-11-03 1977-07-12 Richter Gedeon Vegyeszeti Gyar Rt. Alkaloid esters
GB1550496A (en) * 1976-12-31 1979-08-15 Logeais Labor Jacques 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications
GB2005267B (en) * 1977-09-30 1982-05-19 Omnium Chimique Sa Indole derivatives their preparation and pharmaceutical compositions containing them
JPS5732281A (en) * 1980-08-06 1982-02-20 Sumitomo Chem Co Ltd Nitrogen-containing polycyclic compound and its preparation
EP0079411B1 (fr) * 1981-11-18 1987-02-04 Thal, Claude Dérivés d'indoloquinolizine, leur procédé de préparation et leur application en thérapeutique
FR2517679A1 (fr) * 1981-12-03 1983-06-10 Synthelabo Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique
DE3204960A1 (de) * 1982-02-12 1983-08-25 Fa. Dr. Willmar Schwabe, 7500 Karlsruhe Corynanthein-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4565872A (en) * 1982-06-07 1986-01-21 Riker Laboratories, Inc. Process for 8-cyano-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids and intermediates thereof
US4482714A (en) * 1983-01-26 1984-11-13 American Home Products Corporation Pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives
GB8416724D0 (en) * 1984-06-30 1984-08-01 Sorbio Sa Lab Active compounds

Also Published As

Publication number Publication date
FI864891A0 (fi) 1986-12-01
PT83801B (en) 1988-02-22
ZA868752B (en) 1988-07-27
AU6556286A (en) 1987-06-25
FI864891A (fi) 1987-06-21
IL80658A0 (en) 1987-02-27
JPS62148487A (ja) 1987-07-02
US4624954A (en) 1986-11-25
DK618886D0 (da) 1986-12-19
EP0228825A1 (en) 1987-07-15
KR870006048A (ko) 1987-07-08
PT83801A (en) 1986-12-01
HUT45249A (en) 1988-06-28

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Legal Events

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AHB Application shelved due to non-payment