IL80658A0 - 6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing them - Google Patents
6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL80658A0 IL80658A0 IL80658A IL8065886A IL80658A0 IL 80658 A0 IL80658 A0 IL 80658A0 IL 80658 A IL80658 A IL 80658A IL 8065886 A IL8065886 A IL 8065886A IL 80658 A0 IL80658 A0 IL 80658A0
- Authority
- IL
- Israel
- Prior art keywords
- pyrido
- indol
- tetrahydro
- amines
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/811,551 US4624954A (en) | 1985-12-20 | 1985-12-20 | 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments |
Publications (1)
Publication Number | Publication Date |
---|---|
IL80658A0 true IL80658A0 (en) | 1987-02-27 |
Family
ID=25206862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL80658A IL80658A0 (en) | 1985-12-20 | 1986-11-17 | 6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing them |
Country Status (11)
Country | Link |
---|---|
US (1) | US4624954A (xx) |
EP (1) | EP0228825A1 (xx) |
JP (1) | JPS62148487A (xx) |
KR (1) | KR870006048A (xx) |
AU (1) | AU6556286A (xx) |
DK (1) | DK618886A (xx) |
FI (1) | FI864891A (xx) |
HU (1) | HUT45249A (xx) |
IL (1) | IL80658A0 (xx) |
PT (1) | PT83801B (xx) |
ZA (1) | ZA868752B (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8416724D0 (en) * | 1984-06-30 | 1984-08-01 | Sorbio Sa Lab | Active compounds |
DE3677101D1 (de) * | 1985-06-28 | 1991-02-28 | Beecham Wuelfing Gmbh & Co Kg | Tetrahydropyrido-(1,2-a)-indolderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. |
EP0252643A1 (en) * | 1986-07-01 | 1988-01-13 | BEECHAM - WUELFING GmbH & Co. KG | Pyrido[1,2-a]indole derivatives, process for their preparation and pharmaceutical compounds containing them |
US4778812A (en) * | 1987-06-12 | 1988-10-18 | American Home Products Corporation | 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives thereof |
TW200800959A (en) * | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
EP1893617A1 (en) * | 2005-06-17 | 2008-03-05 | Wyeth a Corporation of the State of Delaware | Tricyclic compounds useful as serotonin inhibitors and 5-ht1a agonists and antagonists |
TW200808740A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof |
TW200808741A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts |
TW200811144A (en) * | 2006-06-09 | 2008-03-01 | Wyeth Corp | Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline |
TW200831096A (en) * | 2006-11-28 | 2008-08-01 | Wyeth Corp | Metabolites of 5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl} quinoline and methods of preparation and uses thereof |
CL2008000119A1 (es) | 2007-01-16 | 2008-05-16 | Wyeth Corp | Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia. |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4035370A (en) * | 1971-11-03 | 1977-07-12 | Richter Gedeon Vegyeszeti Gyar Rt. | Alkaloid esters |
GB1550496A (en) * | 1976-12-31 | 1979-08-15 | Logeais Labor Jacques | 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications |
GB2005267B (en) * | 1977-09-30 | 1982-05-19 | Omnium Chimique Sa | Indole derivatives their preparation and pharmaceutical compositions containing them |
JPS5732281A (en) * | 1980-08-06 | 1982-02-20 | Sumitomo Chem Co Ltd | Nitrogen-containing polycyclic compound and its preparation |
EP0079411B1 (fr) * | 1981-11-18 | 1987-02-04 | Thal, Claude | Dérivés d'indoloquinolizine, leur procédé de préparation et leur application en thérapeutique |
FR2517679A1 (fr) * | 1981-12-03 | 1983-06-10 | Synthelabo | Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique |
DE3204960A1 (de) * | 1982-02-12 | 1983-08-25 | Fa. Dr. Willmar Schwabe, 7500 Karlsruhe | Corynanthein-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4565872A (en) * | 1982-06-07 | 1986-01-21 | Riker Laboratories, Inc. | Process for 8-cyano-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids and intermediates thereof |
US4482714A (en) * | 1983-01-26 | 1984-11-13 | American Home Products Corporation | Pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives |
GB8416724D0 (en) * | 1984-06-30 | 1984-08-01 | Sorbio Sa Lab | Active compounds |
-
1985
- 1985-12-20 US US06/811,551 patent/US4624954A/en not_active Expired - Lifetime
-
1986
- 1986-11-17 IL IL80658A patent/IL80658A0/xx unknown
- 1986-11-18 ZA ZA868752A patent/ZA868752B/xx unknown
- 1986-11-21 AU AU65562/86A patent/AU6556286A/en not_active Abandoned
- 1986-11-25 PT PT83801A patent/PT83801B/pt unknown
- 1986-12-01 FI FI864891A patent/FI864891A/fi not_active Application Discontinuation
- 1986-12-03 EP EP86309431A patent/EP0228825A1/en not_active Withdrawn
- 1986-12-08 JP JP61292259A patent/JPS62148487A/ja active Pending
- 1986-12-08 HU HU865098A patent/HUT45249A/hu unknown
- 1986-12-18 KR KR860010894A patent/KR870006048A/ko not_active Application Discontinuation
- 1986-12-19 DK DK618886A patent/DK618886A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU6556286A (en) | 1987-06-25 |
DK618886D0 (da) | 1986-12-19 |
PT83801A (en) | 1986-12-01 |
DK618886A (da) | 1987-06-21 |
FI864891A (fi) | 1987-06-21 |
US4624954A (en) | 1986-11-25 |
JPS62148487A (ja) | 1987-07-02 |
KR870006048A (ko) | 1987-07-08 |
PT83801B (en) | 1988-02-22 |
ZA868752B (en) | 1988-07-27 |
HUT45249A (en) | 1988-06-28 |
EP0228825A1 (en) | 1987-07-15 |
FI864891A0 (fi) | 1986-12-01 |
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