DK597083A - 16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling - Google Patents

16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling Download PDF

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Publication number
DK597083A
DK597083A DK597083A DK597083A DK597083A DK 597083 A DK597083 A DK 597083A DK 597083 A DK597083 A DK 597083A DK 597083 A DK597083 A DK 597083A DK 597083 A DK597083 A DK 597083A
Authority
DK
Denmark
Prior art keywords
sub
ketoandrosten
dithioketals
procedure
preparation
Prior art date
Application number
DK597083A
Other languages
Danish (da)
English (en)
Other versions
DK597083D0 (da
Inventor
Ravi K Varma
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of DK597083D0 publication Critical patent/DK597083D0/da
Publication of DK597083A publication Critical patent/DK597083A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/04Thiosulfonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK597083A 1982-12-27 1983-12-23 16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling DK597083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/453,314 US4420428A (en) 1982-12-27 1982-12-27 16-Ketoandrostene-17-dithioketals

Publications (2)

Publication Number Publication Date
DK597083D0 DK597083D0 (da) 1983-12-23
DK597083A true DK597083A (da) 1984-06-28

Family

ID=23800054

Family Applications (1)

Application Number Title Priority Date Filing Date
DK597083A DK597083A (da) 1982-12-27 1983-12-23 16-ketoandrosten-17-dithioketaler og fremgangsmaade til deres fremstilling

Country Status (10)

Country Link
US (1) US4420428A (de)
EP (1) EP0112758B1 (de)
JP (1) JPS59122500A (de)
AT (1) ATE21518T1 (de)
CA (1) CA1205462A (de)
DE (1) DE3365482D1 (de)
DK (1) DK597083A (de)
HU (1) HU187099B (de)
IE (1) IE56420B1 (de)
ZA (1) ZA839077B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427592A (en) * 1983-01-31 1984-01-24 E. R. Squibb & Sons, Inc. Androstene-17-dithioketals
US4499021A (en) * 1984-04-12 1985-02-12 E. R. Squibb & Sons, Inc. 17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
US4528138A (en) * 1984-06-20 1985-07-09 E. R. Squibb & Sons, Inc. 16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes
US4891367A (en) * 1987-04-22 1990-01-02 Merrell Dow Pharmaceuticals Inc. 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
AU725048B2 (en) * 1996-05-09 2000-10-05 Amrad Operations Pty. Limited Treatment of asthma and airway diseases
CA2253943C (en) * 1996-05-09 2009-09-29 Amrad Operations Pty. Ltd. Treatment of asthma and airway diseases
CN114790157B (zh) * 2022-02-28 2024-06-21 开封大地农化生物科技有限公司 一种高含量乙蒜素的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094840A (en) * 1977-05-12 1978-06-13 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) * 1978-02-17 1979-01-09 E. R. Squibb & Sons, Inc. 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) * 1978-02-27 1979-03-27 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones
US4252733A (en) * 1980-03-31 1981-02-24 E. R. Squibb & Sons, Inc. 17-Substituted sulfonyl-16,16-disubstituted androstenes
US4361559A (en) * 1981-08-20 1982-11-30 E. R. Squibb & Sons, Inc. Antiinflammatory 17,17-bis (substituted thio) androstenes

Also Published As

Publication number Publication date
ATE21518T1 (de) 1986-09-15
CA1205462A (en) 1986-06-03
JPS59122500A (ja) 1984-07-14
IE832999L (en) 1984-06-27
HU187099B (en) 1985-11-28
EP0112758B1 (de) 1986-08-20
US4420428A (en) 1983-12-13
ZA839077B (en) 1984-07-25
DE3365482D1 (de) 1986-09-25
IE56420B1 (en) 1991-07-31
DK597083D0 (da) 1983-12-23
EP0112758A1 (de) 1984-07-04

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment