ZA839077B - 16-ketoandrostene-17-dithioketals - Google Patents

16-ketoandrostene-17-dithioketals

Info

Publication number
ZA839077B
ZA839077B ZA839077A ZA839077A ZA839077B ZA 839077 B ZA839077 B ZA 839077B ZA 839077 A ZA839077 A ZA 839077A ZA 839077 A ZA839077 A ZA 839077A ZA 839077 B ZA839077 B ZA 839077B
Authority
ZA
South Africa
Prior art keywords
sub
ketoandrostene
dithioketals
halogen
hydrogen
Prior art date
Application number
ZA839077A
Other languages
English (en)
Inventor
Kannadikovilakom Varma Ravi
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ZA839077B publication Critical patent/ZA839077B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/04—Thiosulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA839077A 1982-12-27 1983-12-06 16-ketoandrostene-17-dithioketals ZA839077B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/453,314 US4420428A (en) 1982-12-27 1982-12-27 16-Ketoandrostene-17-dithioketals

Publications (1)

Publication Number Publication Date
ZA839077B true ZA839077B (en) 1984-07-25

Family

ID=23800054

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA839077A ZA839077B (en) 1982-12-27 1983-12-06 16-ketoandrostene-17-dithioketals

Country Status (10)

Country Link
US (1) US4420428A (de)
EP (1) EP0112758B1 (de)
JP (1) JPS59122500A (de)
AT (1) ATE21518T1 (de)
CA (1) CA1205462A (de)
DE (1) DE3365482D1 (de)
DK (1) DK597083A (de)
HU (1) HU187099B (de)
IE (1) IE56420B1 (de)
ZA (1) ZA839077B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427592A (en) * 1983-01-31 1984-01-24 E. R. Squibb & Sons, Inc. Androstene-17-dithioketals
US4499021A (en) * 1984-04-12 1985-02-12 E. R. Squibb & Sons, Inc. 17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
US4528138A (en) * 1984-06-20 1985-07-09 E. R. Squibb & Sons, Inc. 16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes
US4891367A (en) * 1987-04-22 1990-01-02 Merrell Dow Pharmaceuticals Inc. 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
EP0923376B1 (de) * 1996-05-09 2004-11-03 Amrad Operations Pty.,Ltd. Verwendung von steroiden zur behandlung von asthma und atemwegerkrankungen
AU725048B2 (en) * 1996-05-09 2000-10-05 Amrad Operations Pty. Limited Treatment of asthma and airway diseases
CN114790157B (zh) * 2022-02-28 2024-06-21 开封大地农化生物科技有限公司 一种高含量乙蒜素的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094840A (en) * 1977-05-12 1978-06-13 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) * 1978-02-17 1979-01-09 E. R. Squibb & Sons, Inc. 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) * 1978-02-27 1979-03-27 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones
US4252733A (en) * 1980-03-31 1981-02-24 E. R. Squibb & Sons, Inc. 17-Substituted sulfonyl-16,16-disubstituted androstenes
US4361559A (en) * 1981-08-20 1982-11-30 E. R. Squibb & Sons, Inc. Antiinflammatory 17,17-bis (substituted thio) androstenes

Also Published As

Publication number Publication date
HU187099B (en) 1985-11-28
US4420428A (en) 1983-12-13
DK597083A (da) 1984-06-28
CA1205462A (en) 1986-06-03
EP0112758A1 (de) 1984-07-04
EP0112758B1 (de) 1986-08-20
DE3365482D1 (de) 1986-09-25
ATE21518T1 (de) 1986-09-15
IE56420B1 (en) 1991-07-31
IE832999L (en) 1984-06-27
DK597083D0 (da) 1983-12-23
JPS59122500A (ja) 1984-07-14

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