ATE21518T1 - 16-keto-androsten-17-dithioketale. - Google Patents

16-keto-androsten-17-dithioketale.

Info

Publication number
ATE21518T1
ATE21518T1 AT83402376T AT83402376T ATE21518T1 AT E21518 T1 ATE21518 T1 AT E21518T1 AT 83402376 T AT83402376 T AT 83402376T AT 83402376 T AT83402376 T AT 83402376T AT E21518 T1 ATE21518 T1 AT E21518T1
Authority
AT
Austria
Prior art keywords
sub
androsene
dithioketals
keto
halogen
Prior art date
Application number
AT83402376T
Other languages
English (en)
Inventor
Ravi K Varma
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Application granted granted Critical
Publication of ATE21518T1 publication Critical patent/ATE21518T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/04—Thiosulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT83402376T 1982-12-27 1983-12-08 16-keto-androsten-17-dithioketale. ATE21518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/453,314 US4420428A (en) 1982-12-27 1982-12-27 16-Ketoandrostene-17-dithioketals
EP83402376A EP0112758B1 (de) 1982-12-27 1983-12-08 16-Keto-Androsten-17-Dithioketale

Publications (1)

Publication Number Publication Date
ATE21518T1 true ATE21518T1 (de) 1986-09-15

Family

ID=23800054

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83402376T ATE21518T1 (de) 1982-12-27 1983-12-08 16-keto-androsten-17-dithioketale.

Country Status (10)

Country Link
US (1) US4420428A (de)
EP (1) EP0112758B1 (de)
JP (1) JPS59122500A (de)
AT (1) ATE21518T1 (de)
CA (1) CA1205462A (de)
DE (1) DE3365482D1 (de)
DK (1) DK597083A (de)
HU (1) HU187099B (de)
IE (1) IE56420B1 (de)
ZA (1) ZA839077B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427592A (en) * 1983-01-31 1984-01-24 E. R. Squibb & Sons, Inc. Androstene-17-dithioketals
US4499021A (en) * 1984-04-12 1985-02-12 E. R. Squibb & Sons, Inc. 17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
US4528138A (en) * 1984-06-20 1985-07-09 E. R. Squibb & Sons, Inc. 16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes
US4891367A (en) * 1987-04-22 1990-01-02 Merrell Dow Pharmaceuticals Inc. 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
AU725048B2 (en) * 1996-05-09 2000-10-05 Amrad Operations Pty. Limited Treatment of asthma and airway diseases
US5962445A (en) * 1996-05-09 1999-10-05 Amrad Operations Pty Ltd. Treatment of asthma and airway diseases
CN114790157A (zh) * 2022-02-28 2022-07-26 开封大地农化生物科技有限公司 一种高含量乙蒜素的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094840A (en) * 1977-05-12 1978-06-13 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) * 1978-02-17 1979-01-09 E. R. Squibb & Sons, Inc. 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) * 1978-02-27 1979-03-27 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones
US4252733A (en) * 1980-03-31 1981-02-24 E. R. Squibb & Sons, Inc. 17-Substituted sulfonyl-16,16-disubstituted androstenes
US4361559A (en) * 1981-08-20 1982-11-30 E. R. Squibb & Sons, Inc. Antiinflammatory 17,17-bis (substituted thio) androstenes

Also Published As

Publication number Publication date
EP0112758B1 (de) 1986-08-20
DK597083D0 (da) 1983-12-23
DE3365482D1 (de) 1986-09-25
JPS59122500A (ja) 1984-07-14
EP0112758A1 (de) 1984-07-04
US4420428A (en) 1983-12-13
DK597083A (da) 1984-06-28
HU187099B (en) 1985-11-28
CA1205462A (en) 1986-06-03
ZA839077B (en) 1984-07-25
IE56420B1 (en) 1991-07-31
IE832999L (en) 1984-06-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee