DK585485A - Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse - Google Patents

Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse Download PDF

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Publication number
DK585485A
DK585485A DK585485A DK585485A DK585485A DK 585485 A DK585485 A DK 585485A DK 585485 A DK585485 A DK 585485A DK 585485 A DK585485 A DK 585485A DK 585485 A DK585485 A DK 585485A
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DK
Denmark
Prior art keywords
derivative
procedures
preparing
compound
pharmaceutical preparation
Prior art date
Application number
DK585485A
Other languages
Danish (da)
English (en)
Other versions
DK585485D0 (da
Inventor
Minoru Uchida
Seiji Morita
Masatoshi Chihiro
Kazuyuki Nakagawa
Original Assignee
Utsuka Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59267061A external-priority patent/JPS61145182A/ja
Priority claimed from JP60145654A external-priority patent/JPH0625060B2/ja
Priority claimed from JP60252489A external-priority patent/JPH0633255B2/ja
Application filed by Utsuka Pharm Co Ltd filed Critical Utsuka Pharm Co Ltd
Publication of DK585485D0 publication Critical patent/DK585485D0/da
Publication of DK585485A publication Critical patent/DK585485A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C07D215/60—N-oxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK585485A 1984-12-18 1985-12-17 Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse DK585485A (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP59267061A JPS61145182A (ja) 1984-12-18 1984-12-18 イミダゾピリジン誘導体
JP59271433 1984-12-21
JP60145654A JPH0625060B2 (ja) 1985-07-02 1985-07-02 抗潰瘍剤
JP15470885 1985-07-12
JP60252489A JPH0633255B2 (ja) 1984-12-21 1985-11-11 テトラヒドロキノリン誘導体

Publications (2)

Publication Number Publication Date
DK585485D0 DK585485D0 (da) 1985-12-17
DK585485A true DK585485A (da) 1986-08-08

Family

ID=27527742

Family Applications (1)

Application Number Title Priority Date Filing Date
DK585485A DK585485A (da) 1984-12-18 1985-12-17 Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse

Country Status (4)

Country Link
US (2) US4738970A (fr)
EP (1) EP0187977B1 (fr)
DE (1) DE3579436D1 (fr)
DK (1) DK585485A (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8505492D0 (en) * 1985-03-04 1985-04-03 Roussel Lab Ltd Chemical compounds
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
US4963566A (en) * 1986-03-28 1990-10-16 Otsuka Pharmaceutical Co., Ltd. Benzimidazolyl-sulfinyl-tetrahydroquinolines
JPH0643426B2 (ja) * 1986-07-25 1994-06-08 東京田辺製薬株式会社 イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
JPH01261386A (ja) * 1988-04-11 1989-10-18 Nisshin Flour Milling Co Ltd 新規な２―ピリジルメチルチオ誘導体及びそれを含有する抗潰瘍剤
US5200407A (en) * 1989-06-29 1993-04-06 Meiji Seika Kaburhiki Kaisha Azole derivatives and anti-ulcerative composition containing same
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
EP0434999B1 (fr) * 1989-11-29 1994-08-17 Toa Eiyo Ltd. Dérivés de cyclohepténopyridine, procédé de leur préparation et les agents anti-ulcère les contenant
US5081253A (en) * 1989-12-21 1992-01-14 American Home Products Corporation Imidazo(4,5-c)pyridines as antiosteoporotic agents
AU634880B2 (en) * 1990-03-28 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Quinoline derivative, antiulcer drug containing the same, and production of said derivative
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
TW200606163A (en) 2004-04-22 2006-02-16 Eisai Co Ltd Imidazopyridine compound
TW200613301A (en) * 2004-06-15 2006-05-01 Altana Pharma Ag Novel amino-halogen-imidazopyridines
US20070015782A1 (en) 2005-04-15 2007-01-18 Eisai Co., Ltd. Benzimidazole compound
US9040564B2 (en) 2005-04-28 2015-05-26 Eisai R&D Management Co., Ltd. Stabilized composition
CN108358953B (zh) * 2018-03-07 2020-07-03 沈阳药科大学 铜与咪唑并吡啶类化合物的配合物及其应用
US11666562B2 (en) 2020-04-02 2023-06-06 Northwestern University Ilaprazole for inhibiting the release of enveloped viruses from cells
WO2021217187A1 (fr) * 2020-04-23 2021-10-28 Northwestern University Inhibiteurs à petites molécules bloquant le bourgeonnement de virus enveloppés

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (fr) * 1968-10-21 1971-06-03
US3819640A (en) * 1972-08-07 1974-06-25 Degussa Aza-benzimidazoles and process for their production
US4011225A (en) * 1972-10-21 1977-03-08 John Wyeth & Brother Limited 8-cyano-5,6,7,8-tetrahydroquinoline derivatives
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
DE3137996A1 (de) * 1981-09-24 1983-04-28 Hoechst Ag, 6230 Frankfurt Heterocyclische phenylaether, verfahren zu deren herstellung und diese enthaltende herbizide mittel
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
GB8311652D0 (en) * 1983-04-28 1983-06-02 Wyeth John & Brother Ltd Heterocyclic compounds
CA1259070A (fr) * 1983-07-01 1989-09-05 Upjohn Company (The) Derives de substitution de 2-¬noyaux condenses (3,4- 4,5-, 5,6-)-pyridylalcoylenesulfinyl|- benzimidazoles
JPS62145084A (ja) * 1985-12-20 1987-06-29 Tokyo Tanabe Co Ltd イミダゾ〔４，５−ｂ〕ピリジン誘導体
JPH0643426B2 (ja) * 1986-07-25 1994-06-08 東京田辺製薬株式会社 イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤

Also Published As

Publication number Publication date
US4738970A (en) 1988-04-19
EP0187977A1 (fr) 1986-07-23
DE3579436D1 (de) 1990-10-04
US4880815A (en) 1989-11-14
EP0187977B1 (fr) 1990-08-29
DK585485D0 (da) 1985-12-17

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