DK544682A - N-hydroxyethylerede 2,4,6-trijodaminoisophthalsyre-bis-trihydroxybutylamider, deres fremstilling og roentgenkontrastmidler indeholdende dem - Google Patents
N-hydroxyethylerede 2,4,6-trijodaminoisophthalsyre-bis-trihydroxybutylamider, deres fremstilling og roentgenkontrastmidler indeholdende dem Download PDFInfo
- Publication number
- DK544682A DK544682A DK544682A DK544682A DK544682A DK 544682 A DK544682 A DK 544682A DK 544682 A DK544682 A DK 544682A DK 544682 A DK544682 A DK 544682A DK 544682 A DK544682 A DK 544682A
- Authority
- DK
- Denmark
- Prior art keywords
- xentic
- trijodaminoisophthalic
- trihydroxybutylamides
- hydroxyethylered
- bis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813150916 DE3150916A1 (de) | 1981-12-18 | 1981-12-18 | N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel" |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK544682A true DK544682A (da) | 1983-06-19 |
Family
ID=6149449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK544682A DK544682A (da) | 1981-12-18 | 1982-12-08 | N-hydroxyethylerede 2,4,6-trijodaminoisophthalsyre-bis-trihydroxybutylamider, deres fremstilling og roentgenkontrastmidler indeholdende dem |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4547357A (da) |
| EP (1) | EP0082803A1 (da) |
| JP (1) | JPS58110551A (da) |
| AU (1) | AU9165482A (da) |
| CA (1) | CA1189533A (da) |
| DE (1) | DE3150916A1 (da) |
| DK (1) | DK544682A (da) |
| ES (1) | ES8308535A1 (da) |
| GR (1) | GR78422B (da) |
| NO (1) | NO824252L (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204086A (en) * | 1982-10-01 | 1993-04-20 | Nycomed Imaging As | X-ray contrast agent |
| US4584401A (en) * | 1983-10-20 | 1986-04-22 | Biophysica Foundation | Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media |
| US4954348A (en) * | 1985-08-09 | 1990-09-04 | Cook Imaging Corporation | Non-ionic polyol contrast media from ionic contrast media |
| EP0233249B1 (en) * | 1985-08-09 | 1993-11-24 | Cook Imaging Corporation | Non-ionic polyol contrast media from ionic contrast media |
| US5035877A (en) * | 1985-08-09 | 1991-07-30 | Cook Imaging Corporation | Non-ionic contrast media from ionic contrast media |
| JPH0420687Y2 (da) * | 1986-10-21 | 1992-05-12 | ||
| KR960016747B1 (ko) * | 1987-05-22 | 1996-12-20 | 브라코 인터내셔날 비. 브이 | 5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법 |
| US5698739A (en) * | 1989-07-05 | 1997-12-16 | Schering Aktiengesellschaft | Carboxamide non-ionic contrast media |
| IL94718A (en) * | 1989-07-05 | 1994-10-21 | Schering Ag | Non-ionic carboxamide contrast agent and method of preparation |
| US5614638A (en) * | 1989-11-29 | 1997-03-25 | Bracco International B.V. | Nonionic radiographic contrast agents |
| CA2029830A1 (en) * | 1989-11-29 | 1991-05-30 | Ramachandran S. Ranganathan | Nonionic radiographic contrast agents |
| DE4009119A1 (de) * | 1990-03-19 | 1991-09-26 | Schering Ag | 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| DE4109169A1 (de) * | 1991-03-20 | 1992-09-24 | Koehler Chemie Dr Franz | Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung |
| US5318770A (en) * | 1991-10-25 | 1994-06-07 | Mallinckrodt Medical, Inc. | Trifluoromethyl analogs of X-ray contrast media for magnetic resonance imaging |
| FR2687669B1 (fr) * | 1992-02-24 | 1997-12-19 | Guerbet Sa | Composes utilisables dans des produits de contraste pour la radiographie. |
| US5278311A (en) * | 1992-06-05 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Nonionic radiographic contrast agents |
| IT1256162B (it) * | 1992-10-27 | 1995-11-29 | Zambon Spa | Processo per la preparazione di un intermedio della sintesi organica |
| IL110391A (en) * | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the formation of infamidol |
| WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
| AU2017333698B2 (en) | 2016-09-27 | 2020-12-24 | Bayer Pharma Aktiengesellschaft | Method for producing the crystalline form of modification a of calcobutrol |
| CN110023279B (zh) * | 2016-12-05 | 2022-03-11 | 伯拉考成像股份公司 | 放射照相剂中间体的机械化学合成 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021481A (en) * | 1969-06-27 | 1977-05-03 | Nyegaard & Co. A/S | Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups |
| US3701771A (en) * | 1969-06-27 | 1972-10-31 | Nyegaard & Co As | N-(2,4,6-triiodobenzoyl)-sugar amines |
| GB1495679A (en) * | 1974-06-17 | 1977-12-21 | Mallinckrodt Inc | Substituted isophthalamic acids |
| CH608189A5 (da) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
| US4278654A (en) * | 1978-07-04 | 1981-07-14 | Nyegaard & Co. A/S | Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer |
| DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
| IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
| US4341756A (en) * | 1980-01-31 | 1982-07-27 | The Regents Of The University Of California | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
| US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
-
1981
- 1981-12-18 DE DE19813150916 patent/DE3150916A1/de active Granted
-
1982
- 1982-12-08 DK DK544682A patent/DK544682A/da not_active Application Discontinuation
- 1982-12-14 ES ES518180A patent/ES8308535A1/es not_active Expired
- 1982-12-16 GR GR70102A patent/GR78422B/el unknown
- 1982-12-16 JP JP57219354A patent/JPS58110551A/ja active Granted
- 1982-12-16 EP EP82730146A patent/EP0082803A1/de not_active Withdrawn
- 1982-12-17 CA CA000418020A patent/CA1189533A/en not_active Expired
- 1982-12-17 NO NO824252A patent/NO824252L/no unknown
- 1982-12-20 AU AU91654/82A patent/AU9165482A/en not_active Abandoned
- 1982-12-20 US US06/451,374 patent/US4547357A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GR78422B (da) | 1984-09-27 |
| DE3150916C2 (da) | 1990-11-22 |
| JPS58110551A (ja) | 1983-07-01 |
| US4547357A (en) | 1985-10-15 |
| JPH039900B2 (da) | 1991-02-12 |
| NO824252L (no) | 1983-06-20 |
| DE3150916A1 (de) | 1983-06-30 |
| AU9165482A (en) | 1983-06-23 |
| EP0082803A1 (de) | 1983-06-29 |
| CA1189533A (en) | 1985-06-25 |
| ES518180A0 (es) | 1983-10-01 |
| ES8308535A1 (es) | 1983-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |