DK528680A - Cycliske peptidkerner og fremgangsmaade til fremstilling heraf - Google Patents

Cycliske peptidkerner og fremgangsmaade til fremstilling heraf

Info

Publication number
DK528680A
DK528680A DK528680A DK528680A DK528680A DK 528680 A DK528680 A DK 528680A DK 528680 A DK528680 A DK 528680A DK 528680 A DK528680 A DK 528680A DK 528680 A DK528680 A DK 528680A
Authority
DK
Denmark
Prior art keywords
peptid
cyclic
preparing
core
procedure
Prior art date
Application number
DK528680A
Other languages
Danish (da)
English (en)
Inventor
B J Abbott
D S Fukuda
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/181,449 external-priority patent/US4299762A/en
Priority claimed from US06/181,437 external-priority patent/US4299763A/en
Priority claimed from US06/181,036 external-priority patent/US4304716A/en
Priority claimed from US06/181,029 external-priority patent/US4293482A/en
Priority claimed from US06/181,443 external-priority patent/US4293490A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK528680A publication Critical patent/DK528680A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045Actinoplanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/62Streptosporangium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK528680A 1979-12-13 1980-12-11 Cycliske peptidkerner og fremgangsmaade til fremstilling heraf DK528680A (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US10331379A 1979-12-13 1979-12-13
US10312179A 1979-12-13 1979-12-13
US10301779A 1979-12-13 1979-12-13
US10326879A 1979-12-13 1979-12-13
US10301679A 1979-12-13 1979-12-13
US06/181,449 US4299762A (en) 1979-12-13 1980-08-25 A-30912D Nucleus
US06/181,437 US4299763A (en) 1979-12-13 1980-08-25 A-30912B Nucleus
US06/181,036 US4304716A (en) 1979-12-13 1980-08-25 S 31794/F-1 Nucleus
US06/181,029 US4293482A (en) 1979-12-13 1980-08-25 A-30912A Nucleus
US06/181,443 US4293490A (en) 1979-12-13 1980-08-25 A-30912H Nuclei

Publications (1)

Publication Number Publication Date
DK528680A true DK528680A (da) 1981-06-14

Family

ID=27580999

Family Applications (1)

Application Number Title Priority Date Filing Date
DK528680A DK528680A (da) 1979-12-13 1980-12-11 Cycliske peptidkerner og fremgangsmaade til fremstilling heraf

Country Status (17)

Country Link
EP (1) EP0031221B1 (ko)
JP (1) JPS6425797A (ko)
KR (1) KR840000769B1 (ko)
CA (1) CA1170598A (ko)
CH (1) CH646701A5 (ko)
DD (1) DD155250A5 (ko)
DE (1) DE3062235D1 (ko)
DK (1) DK528680A (ko)
FI (1) FI803872L (ko)
FR (1) FR2484451B1 (ko)
GB (1) GB2065131B (ko)
GR (1) GR72254B (ko)
IL (1) IL61651A (ko)
IT (1) IT1141151B (ko)
PL (1) PL228450A1 (ko)
PT (1) PT72153B (ko)
YU (1) YU311080A (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000587A1 (en) * 1980-08-15 1982-03-04 Tscherter H New metabolites,processes for their production and their use
NZ199196A (en) * 1980-12-18 1985-01-31 Lilly Co Eli Antibiotic a-4696 factor g and growth-promoting compositions;actinoplanes missouriensis atcc 31681
US4322406A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
US4587218A (en) * 1983-10-21 1986-05-06 Eli Lilly And Company Novel bioconverting microorganisms
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
RU2001126723A (ru) 1999-03-03 2003-09-27 Эли Лилли энд Компани (US) Эхинокандин/углеводные комплексы
AU776782C (en) 1999-03-03 2005-04-07 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
CA2362482A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
ES2270819T3 (es) * 1999-03-03 2007-04-16 Eli Lilly And Company Formacion e intercambio anionico de sales de amonio internas cristalinas de equinocandina.
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
CN102618606B (zh) * 2011-01-30 2014-09-10 浙江海正药业股份有限公司 一种棘白菌素生物转化方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3150059A (en) * 1962-12-26 1964-09-22 Lilly Co Eli Penicillin deacylation via actinoplanaceae fermentation
JPS5134916B2 (ko) * 1974-03-06 1976-09-29
ES449582A1 (es) * 1975-07-08 1977-12-01 Sandoz Ag Procedimiento para la produccion de s 31794nf-1.
US4024246A (en) * 1975-10-02 1977-05-17 Eli Lilly And Company Antibiotic A-22082 and process for production thereof
GR61684B (en) * 1975-10-02 1978-12-09 Lilly Co Eli Preparation process of antibiotic a-22082
IE43663B1 (en) * 1975-10-02 1981-04-22 Lilly Co Eli Antibiotic and process for production thereof
US4024245A (en) * 1975-10-02 1977-05-17 Eli Lilly And Company Antibiotic A-30912 and process for production thereof
DE2704030A1 (de) * 1976-02-12 1977-08-18 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
DE2742435A1 (de) * 1976-09-28 1978-04-06 Sandoz Ag Aminoalkylaether der peptide tetrahydro- sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung
DE2803581A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Derivate des tetrahydro-echinocandin b
DE2803584A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Aminoalkylaether der peptide tetrahydro-sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung
BE883593A (fr) * 1979-06-08 1980-12-02 Lilly Co Eli Nouveaux antibiotiques, leur preparation et leur utilisation therapeutique

Also Published As

Publication number Publication date
IT8026634A0 (it) 1980-12-12
EP0031221A1 (en) 1981-07-01
PT72153A (en) 1981-01-01
GR72254B (ko) 1983-10-06
IL61651A (en) 1984-04-30
KR840000769B1 (ko) 1984-06-08
PT72153B (en) 1981-10-28
IT1141151B (it) 1986-10-01
IL61651A0 (en) 1981-01-30
EP0031221B1 (en) 1983-03-02
DE3062235D1 (de) 1983-04-07
GB2065131B (en) 1983-06-22
JPH0353320B2 (ko) 1991-08-14
CA1170598A (en) 1984-07-10
FR2484451B1 (fr) 1985-12-06
DD155250A5 (de) 1982-05-26
YU311080A (en) 1983-02-28
FI803872L (fi) 1981-06-14
GB2065131A (en) 1981-06-24
KR830004215A (ko) 1983-07-06
CH646701A5 (fr) 1984-12-14
JPS6425797A (en) 1989-01-27
FR2484451A1 (fr) 1981-12-18
PL228450A1 (ko) 1981-08-07

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