DK51286A - Desoxyadenosinphosphatforbindelser og fremgangsmaade til fremstilling afdisse - Google Patents

Desoxyadenosinphosphatforbindelser og fremgangsmaade til fremstilling afdisse Download PDF

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Publication number
DK51286A
DK51286A DK51286A DK51286A DK51286A DK 51286 A DK51286 A DK 51286A DK 51286 A DK51286 A DK 51286A DK 51286 A DK51286 A DK 51286A DK 51286 A DK51286 A DK 51286A
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Prior art keywords
desoxyadenosinphosphate
compounds
procedure
preparation
desoxyadenosinphosphate compounds
Prior art date
Application number
DK51286A
Other languages
Danish (da)
English (en)
Other versions
DK51286D0 (da
Inventor
Phillip D Cook
Roland K Robins
Dennis Joseph Mcnamara
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK51286D0 publication Critical patent/DK51286D0/da
Publication of DK51286A publication Critical patent/DK51286A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK51286A 1985-02-05 1986-02-03 Desoxyadenosinphosphatforbindelser og fremgangsmaade til fremstilling afdisse DK51286A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69939185A 1985-02-05 1985-02-05
US06/812,564 US4826823A (en) 1985-02-05 1985-12-31 Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts

Publications (2)

Publication Number Publication Date
DK51286D0 DK51286D0 (da) 1986-02-03
DK51286A true DK51286A (da) 1986-08-06

Family

ID=27106410

Family Applications (1)

Application Number Title Priority Date Filing Date
DK51286A DK51286A (da) 1985-02-05 1986-02-03 Desoxyadenosinphosphatforbindelser og fremgangsmaade til fremstilling afdisse

Country Status (8)

Country Link
US (1) US4826823A (fr)
EP (1) EP0190726B1 (fr)
JP (1) JPS61210095A (fr)
AU (1) AU577661B2 (fr)
CA (1) CA1283656C (fr)
DE (1) DE3671897D1 (fr)
DK (1) DK51286A (fr)
ES (1) ES8707545A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826823A (en) * 1985-02-05 1989-05-02 Warner-Lambert Company Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts
US4719295A (en) * 1985-12-31 1988-01-12 Warner-Lambert Company Compound 2-iodo-2'-deoxyadenosine
US5106837A (en) * 1988-03-16 1992-04-21 The Scripps Research Institute Adenosine derivatives with therapeutic activity
US5310732A (en) * 1986-02-03 1994-05-10 The Scripps Research Institute 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US4908441A (en) * 1988-07-19 1990-03-13 Warner-Lambert Company Deoxyadenosine compounds and methods of making and using the same
CA2001401A1 (fr) * 1988-10-25 1990-04-25 Claude Piantadosi Derives d'ether ou d'ester lipidique contenant une amine quaternaire et composes therapeutiques
GB8921469D0 (en) * 1989-09-22 1989-11-08 Erba Carlo Spa 5'-alkylphosphonylnucleosides as antivirals
US5374626A (en) * 1989-09-22 1994-12-20 Farmitalia Carlo Erba 5'-alkylphosphonylnucleosides as antivirals
WO1991007092A1 (fr) * 1989-11-17 1991-05-30 Applied Biosystems, Inc. Polyphosphates d'alkyle et d'alcenyle et leurs derives de thiophosphate et de selenophosphate utilises comme agents antiviraux
US5137876A (en) * 1990-10-12 1992-08-11 Merck & Co., Inc. Nucleoside antiviral and anti-inflammatory compounds and compositions and methods for using same
US5624913A (en) * 1991-04-05 1997-04-29 Wisconsin Alumni Research Foundation Method reducing TNF-alpha in mammals with cerebral malaria
US5516762A (en) * 1991-04-05 1996-05-14 Wisconsin Alumni Research Foundation Method of treating endotoxin effects with 2-haloadenosine nucleotide analogs
US5492898A (en) * 1991-04-05 1996-02-20 Wisconsin Alumni Research Foundation Method of treating endotoxin effects with 2-methylthio-ATP and analogs
GB9119762D0 (en) 1991-09-16 1991-10-30 Filler Aaron G Particulate agents for nmt
US5424296A (en) * 1993-04-15 1995-06-13 The Scripps Research Institute 2-Halo-2'-deoxyadenosines as therapeutic agents against malignant astrocytoma
WO1994028908A2 (fr) * 1993-06-10 1994-12-22 Wake Forest University (phospho)lipides contre l'infection a virus de l'hepatite b
WO1995010287A1 (fr) * 1993-10-15 1995-04-20 Wisconsin Alumni Research Foundation Analogues de nucleosides puriques substitues et methode de traitement du choc endotoxinique
US5817641A (en) * 1994-07-21 1998-10-06 Thomas Jefferson University Treatment of enterotoxigenic diarrhea with 2-substituted adenosine derivatives
US7135584B2 (en) * 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
JP4259611B2 (ja) 1994-08-29 2009-04-30 ウェイク フォレスト ユニバーシティ ウィルス感染を治療するための脂質アナログ
JPH10512549A (ja) * 1994-12-22 1998-12-02 オーソ・フアーマシユーチカル・コーポレーシヨン 可溶性の２−クロロ−２’−デオキシアデノシン配合物
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
US7309696B2 (en) 2000-10-19 2007-12-18 Wake Forest University Compositions and methods for targeting cancer cells
CN1486289A (zh) * 2001-05-29 2004-03-31 皇家菲利浦电子有限公司 金属-陶瓷的结合
IL160080A0 (en) * 2001-08-31 2004-06-20 Thomson Licensing Sa Sequence counter for an audio visual stream
US20050187191A1 (en) * 2004-02-20 2005-08-25 Kucera Louis S. Methods and compositions for the treatment of respiratory syncytial virus
EP2428201A1 (fr) * 2010-09-08 2012-03-14 Merck Serono S.A. Administration orale de nucléosides monophosphates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3201389A (en) * 1962-09-24 1965-08-17 Kyowa Hakko Kogyo Kk Method for preparing ribonucleoside-5'-phosphates or their salts from ribonucleosides
US3321462A (en) * 1963-07-15 1967-05-23 Syntex Corp Process for the preparation of nucleoside polyphosphates
US3337529A (en) * 1965-05-18 1967-08-22 Schwarz Biores Inc Method for chromatographically separating nucleotides and other organic materials from a mixture containing same
GB1180460A (en) * 1966-12-16 1970-02-04 Asahi Chemical Ind Process for Producing Nucleotides by Selective Phosphorylation of Nucleosides
US3784444A (en) * 1971-10-21 1974-01-08 Kyowa Hakko Kogyo Kk Process for producing 2-substituted 6-amino purine ribotides
GB1358769A (en) * 1971-10-22 1974-07-03 Kyowa Hakko Kogyo Kk Process for producing 2-substituted purine ribotides
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
US4826823A (en) * 1985-02-05 1989-05-02 Warner-Lambert Company Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts

Also Published As

Publication number Publication date
JPS61210095A (ja) 1986-09-18
ES551616A0 (es) 1987-08-01
ES8707545A1 (es) 1987-08-01
DK51286D0 (da) 1986-02-03
EP0190726B1 (fr) 1990-06-13
US4826823A (en) 1989-05-02
CA1283656C (fr) 1991-04-30
EP0190726A3 (en) 1987-07-22
AU5296686A (en) 1986-08-14
EP0190726A2 (fr) 1986-08-13
AU577661B2 (en) 1988-09-29
JPH0427240B2 (fr) 1992-05-11
DE3671897D1 (de) 1990-07-19

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