DK486589A - Stabile oxapenem-3-carboxylsyrer og deres anvendelse som beta-lactamase-inhibitorer - Google Patents

Stabile oxapenem-3-carboxylsyrer og deres anvendelse som beta-lactamase-inhibitorer Download PDF

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Publication number
DK486589A
DK486589A DK486589A DK486589A DK486589A DK 486589 A DK486589 A DK 486589A DK 486589 A DK486589 A DK 486589A DK 486589 A DK486589 A DK 486589A DK 486589 A DK486589 A DK 486589A
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DK
Denmark
Prior art keywords
carboxylic acids
beta
lactamase inhibitors
oxapenem
stable
Prior art date
Application number
DK486589A
Other languages
English (en)
Other versions
DK486589D0 (da
Inventor
Hans-Rudolf Pfaendler
Karl Georg Metzger
Rainer Endermann
Ingo Haller
Hanno Wild
Wolfgang Hartwig
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK486589D0 publication Critical patent/DK486589D0/da
Publication of DK486589A publication Critical patent/DK486589A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK486589A 1988-10-04 1989-10-03 Stabile oxapenem-3-carboxylsyrer og deres anvendelse som beta-lactamase-inhibitorer DK486589A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3833693A DE3833693A1 (de) 1988-10-04 1988-10-04 Stabile oxapenem-3-carbonsaeuren und ihre verwendung als ss-lactamasehemmer

Publications (2)

Publication Number Publication Date
DK486589D0 DK486589D0 (da) 1989-10-03
DK486589A true DK486589A (da) 1990-04-05

Family

ID=6364340

Family Applications (1)

Application Number Title Priority Date Filing Date
DK486589A DK486589A (da) 1988-10-04 1989-10-03 Stabile oxapenem-3-carboxylsyrer og deres anvendelse som beta-lactamase-inhibitorer

Country Status (20)

Country Link
US (1) US5108747A (da)
EP (1) EP0362622B1 (da)
JP (1) JP2654201B2 (da)
KR (1) KR900005977A (da)
CN (1) CN1041596A (da)
AT (1) ATE120369T1 (da)
AU (1) AU623932B2 (da)
CA (1) CA2000058A1 (da)
DD (1) DD284806A5 (da)
DE (2) DE3833693A1 (da)
DK (1) DK486589A (da)
ES (1) ES2071636T3 (da)
FI (1) FI894653A (da)
HU (1) HUT53650A (da)
IE (1) IE68344B1 (da)
IL (1) IL91813A0 (da)
NO (1) NO893727L (da)
NZ (1) NZ230827A (da)
PT (1) PT91873B (da)
ZA (1) ZA897505B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4027928A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Neue 2-tert.substituierte methyl-oxapenem-3-carbonsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung
DE4142423A1 (de) * 1991-12-20 1993-06-24 Pfaendler Hans Rudolf ((ls)-hydroxyalkyl)oxapenem-3-carbonsaeuren und ihre verwendung als betalactamasehemmer
GB9421816D0 (en) * 1994-10-29 1994-12-14 Smithkline Beecham Plc Novel compounds
EP1199077A1 (en) * 2000-10-19 2002-04-24 Amura Limited Stable compositions of oxapenem-3-carboxylic acids by Co-lyophilisation with pharmaceutical carriers
GB2369358A (en) * 2000-10-19 2002-05-29 Amura Ltd Oxapenems and pharmaceutical compositions thereof
ES2310561T3 (es) 2000-10-19 2009-01-16 Amura Limited Composiciones farmaceuticas que contienen acidos oxapenem-3-carboxilicos.
GB0106428D0 (en) * 2001-03-15 2001-05-02 Amura Ltd Antibacterial composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2045236A (en) * 1979-03-26 1980-10-29 Hoechst Uk Ltd Oxapenem derivatives
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren

Also Published As

Publication number Publication date
HUT53650A (en) 1990-11-28
DK486589D0 (da) 1989-10-03
PT91873A (pt) 1990-04-30
FI894653A0 (fi) 1989-10-02
PT91873B (pt) 1995-09-12
IE68344B1 (en) 1996-06-12
CA2000058A1 (en) 1990-04-04
IL91813A0 (en) 1990-06-10
IE893157L (en) 1990-04-04
ZA897505B (en) 1990-07-25
DE58909140D1 (de) 1995-05-04
ATE120369T1 (de) 1995-04-15
JP2654201B2 (ja) 1997-09-17
DE3833693A1 (de) 1990-04-05
JPH02145519A (ja) 1990-06-05
EP0362622B1 (de) 1995-03-29
US5108747A (en) 1992-04-28
NO893727L (no) 1990-04-05
KR900005977A (ko) 1990-05-07
NO893727D0 (no) 1989-09-19
AU4233589A (en) 1990-04-12
CN1041596A (zh) 1990-04-25
ES2071636T3 (es) 1995-07-01
FI894653A (fi) 1990-04-05
DD284806A5 (de) 1990-11-28
AU623932B2 (en) 1992-05-28
EP0362622A1 (de) 1990-04-11
NZ230827A (en) 1991-05-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment