DK485287A - Megakaryocyt-stimulerende faktor og fremgangsmaade til at isolere en saadan faktor - Google Patents

Megakaryocyt-stimulerende faktor og fremgangsmaade til at isolere en saadan faktor

Info

Publication number
DK485287A
DK485287A DK485287A DK485287A DK485287A DK 485287 A DK485287 A DK 485287A DK 485287 A DK485287 A DK 485287A DK 485287 A DK485287 A DK 485287A DK 485287 A DK485287 A DK 485287A
Authority
DK
Denmark
Prior art keywords
msf
protein
homogeneity
column
factor
Prior art date
Application number
DK485287A
Other languages
English (en)
Other versions
DK485287D0 (da
Inventor
Robert D Rosenberg
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of DK485287D0 publication Critical patent/DK485287D0/da
Publication of DK485287A publication Critical patent/DK485287A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/834—Urine; urinary system
    • Y10S530/835—Kidney

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK485287A 1986-09-17 1987-09-16 Megakaryocyt-stimulerende faktor og fremgangsmaade til at isolere en saadan faktor DK485287A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/908,183 US4894440A (en) 1986-09-17 1986-09-17 Method of isolating megakaryocyte stimulatory factor

Publications (2)

Publication Number Publication Date
DK485287D0 DK485287D0 (da) 1987-09-16
DK485287A true DK485287A (da) 1988-03-18

Family

ID=25425332

Family Applications (1)

Application Number Title Priority Date Filing Date
DK485287A DK485287A (da) 1986-09-17 1987-09-16 Megakaryocyt-stimulerende faktor og fremgangsmaade til at isolere en saadan faktor

Country Status (9)

Country Link
US (1) US4894440A (da)
EP (1) EP0260918B1 (da)
JP (1) JPS63239298A (da)
AT (1) ATE87212T1 (da)
AU (1) AU598297B2 (da)
DE (1) DE3784992D1 (da)
DK (1) DK485287A (da)
PT (1) PT85730B (da)
ZA (1) ZA876860B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90719A0 (en) * 1988-06-28 1990-01-18 Yissum Res Dev Co Novel nuclei acids and polypeptides encoded thereby
IL88831A0 (en) * 1988-12-29 1989-07-31 Yeda Res & Dev Blood assay
US5032396A (en) * 1989-02-17 1991-07-16 Immunex Corporation IL-7 to stimulate platelet production
US5260417A (en) * 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
US6433142B1 (en) 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
EP0540575A4 (en) * 1990-07-02 1994-06-08 Hipple Cancer Res Center Human meg-csf protein and methods
KR927003795A (ko) * 1990-10-05 1992-12-18 시스테믹스, 인코포레이티드 거핵세포 및 혈소판 성장, 제조방법 및 이것들을 포함하는 조성물
JPH05503302A (ja) * 1990-10-12 1993-06-03 アムジエン・インコーポレーテツド 巨核球成熟因子
AU646530B2 (en) * 1990-12-28 1994-02-24 Asahi Kasei Kogyo Kabushiki Kaisha Novel megakaryocyte amplifier and production thereof
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法
US5482924A (en) * 1991-05-06 1996-01-09 Centre National De La Recherche Proteinaceous compositions having an activity on erythropoiesis
AU2296992A (en) * 1991-06-28 1993-01-25 New England Deaconess Hospital A differentiated megakaryocyte line producing novel megakaryocyte differentiation factors
AU4190893A (en) * 1992-07-17 1994-01-20 Suntory Limited Megakaryocyte differentiation factor
IL139335A (en) * 1994-01-03 2005-08-31 Genentech Inc Mpl ligand polypeptides, nucleic acids encoding them, vectors and host cells comprising such nucleic acids, processes for producing such polypeptides pharmaceutical compositions containing them and use thereof in the preparation of medicaments for treating thrombocytopenia
US6660256B1 (en) * 1994-01-03 2003-12-09 Genetech, Inc. Porcine mpl ligand
US8192955B1 (en) 1994-01-03 2012-06-05 Genentech, Inc. Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
US8357513B1 (en) 1994-01-03 2013-01-22 Genentech, Inc. Nucleic acids encoding mpl ligand (thrombopoietin) and fragments thereof
US8241900B1 (en) 1994-01-03 2012-08-14 Genentech, Inc. mpl ligand
US8147844B1 (en) 1994-01-03 2012-04-03 Genentech, Inc. Mpl ligand (thrombopoietin), nucleic acids encoding such, and methods of treatment using mpl ligand
US8278099B1 (en) 1994-02-15 2012-10-02 Genentech, Inc. Monoclonal antibody to human thrombopoietin
WO1995026746A1 (en) * 1994-03-31 1995-10-12 Amgen Inc. Compositions and methods for stimulating megakaryocyte growth and differentiation
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
US5593666A (en) * 1994-08-16 1997-01-14 The University Of Tennessee Research Corp. Methods and compositions for treating thrombocytopenia
US6013067A (en) * 1995-06-07 2000-01-11 Zymogenetics, Inc. Methods for increasing hematopoietic cells
JPH09143199A (ja) * 1995-11-17 1997-06-03 Nippon Chem Res Kk 血小板第４因子の製造方法
US20030180948A1 (en) * 2000-12-29 2003-09-25 Hutchins Jeff T. Superficial zone protein and methods of making and using same
US20040028661A1 (en) * 2002-08-07 2004-02-12 Bartelmez Stephen H. Expansion of cells using thrombopoietin and anti-transforming growth factor-beta

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN150740B (da) * 1978-11-24 1982-12-04 Hoffmann La Roche

Also Published As

Publication number Publication date
JPS63239298A (ja) 1988-10-05
EP0260918B1 (en) 1993-03-24
US4894440A (en) 1990-01-16
EP0260918A3 (en) 1989-03-22
DE3784992D1 (de) 1993-04-29
ZA876860B (en) 1988-08-31
EP0260918A2 (en) 1988-03-23
AU598297B2 (en) 1990-06-21
PT85730B (pt) 1990-08-31
DK485287D0 (da) 1987-09-16
ATE87212T1 (de) 1993-04-15
PT85730A (en) 1987-10-01
AU7824487A (en) 1988-05-19

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment