DK485177A - Fremgangsmaade til fremstilling af arylsubstituerede benzodiazepiner - Google Patents

Fremgangsmaade til fremstilling af arylsubstituerede benzodiazepiner

Info

Publication number
DK485177A
DK485177A DK485177A DK485177A DK485177A DK 485177 A DK485177 A DK 485177A DK 485177 A DK485177 A DK 485177A DK 485177 A DK485177 A DK 485177A DK 485177 A DK485177 A DK 485177A
Authority
DK
Denmark
Prior art keywords
procedure
making aryl
substituted benzodiazepines
benzodiazepines
substituted
Prior art date
Application number
DK485177A
Other languages
Danish (da)
English (en)
Inventor
D M Zimmerman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK485177A publication Critical patent/DK485177A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK485177A 1976-11-02 1977-11-01 Fremgangsmaade til fremstilling af arylsubstituerede benzodiazepiner DK485177A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/737,959 US4141894A (en) 1976-11-02 1976-11-02 Trans-5a-aryl-decahydrobenzazepines

Publications (1)

Publication Number Publication Date
DK485177A true DK485177A (da) 1978-05-03

Family

ID=24965985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK485177A DK485177A (da) 1976-11-02 1977-11-01 Fremgangsmaade til fremstilling af arylsubstituerede benzodiazepiner

Country Status (26)

Country Link
US (1) US4141894A (US07223432-20070529-C00017.png)
JP (1) JPS5356683A (US07223432-20070529-C00017.png)
AR (1) AR221835A1 (US07223432-20070529-C00017.png)
AT (1) AT358046B (US07223432-20070529-C00017.png)
AU (1) AU510911B2 (US07223432-20070529-C00017.png)
BE (1) BE860315A (US07223432-20070529-C00017.png)
BG (1) BG28417A3 (US07223432-20070529-C00017.png)
CA (2) CA1096861A (US07223432-20070529-C00017.png)
DD (1) DD133797A5 (US07223432-20070529-C00017.png)
DE (1) DE2748468A1 (US07223432-20070529-C00017.png)
DK (1) DK485177A (US07223432-20070529-C00017.png)
ES (1) ES463782A1 (US07223432-20070529-C00017.png)
FR (1) FR2369268A1 (US07223432-20070529-C00017.png)
GB (1) GB1585296A (US07223432-20070529-C00017.png)
GR (1) GR70052B (US07223432-20070529-C00017.png)
IE (1) IE45899B1 (US07223432-20070529-C00017.png)
IL (1) IL53235A0 (US07223432-20070529-C00017.png)
NL (1) NL7712052A (US07223432-20070529-C00017.png)
PH (1) PH13506A (US07223432-20070529-C00017.png)
PL (1) PL108916B1 (US07223432-20070529-C00017.png)
PT (1) PT67195B (US07223432-20070529-C00017.png)
RO (1) RO72899B (US07223432-20070529-C00017.png)
SE (1) SE7712219L (US07223432-20070529-C00017.png)
SU (1) SU843743A3 (US07223432-20070529-C00017.png)
YU (1) YU257577A (US07223432-20070529-C00017.png)
ZA (1) ZA776498B (US07223432-20070529-C00017.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230762B1 (hu) * 2000-07-06 2018-03-28 Daiichi Sankyo Company, Limited Hidropiridin-származékok maleát addíciós sója
FR3062850B1 (fr) * 2017-02-10 2020-01-31 Guerbet Procede de preparation monotope de composes organo-iodes
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA734895B (en) * 1972-07-20 1974-06-26 Du Pont Analgesigs and/or narcotic antagonists
US4001248A (en) * 1974-06-07 1977-01-04 Eli Lilly And Company N-cycloalkylmethyl decahydroisoquinolines
US4001247A (en) * 1974-06-07 1977-01-04 Eli Lilly And Company 1-ethyl 3a-(substituted-phenyl) decahydroisoquinoline

Also Published As

Publication number Publication date
AR221835A1 (es) 1981-03-31
JPS5356683A (en) 1978-05-23
FR2369268B1 (US07223432-20070529-C00017.png) 1980-05-16
PH13506A (en) 1980-06-03
ZA776498B (en) 1979-06-27
PL201883A1 (pl) 1979-01-29
NL7712052A (nl) 1978-05-05
YU257577A (en) 1983-01-21
RO72899B (ro) 1981-03-22
IL53235A0 (en) 1977-12-30
CA1102319A (en) 1981-06-02
IE45899B1 (en) 1982-12-29
CA1096861A (en) 1981-03-03
AU3023377A (en) 1979-05-10
SE7712219L (sv) 1978-05-03
BE860315A (fr) 1978-04-28
FR2369268A1 (fr) 1978-05-26
ES463782A1 (es) 1978-12-16
DD133797A5 (de) 1979-01-24
IE45899L (en) 1978-05-02
GB1585296A (en) 1981-02-25
AU510911B2 (en) 1980-07-17
GR70052B (US07223432-20070529-C00017.png) 1982-07-26
DE2748468A1 (de) 1978-05-03
PT67195B (en) 1979-03-23
ATA782277A (de) 1980-01-15
PT67195A (en) 1977-11-01
SU843743A3 (ru) 1981-06-30
AT358046B (de) 1980-08-11
US4141894A (en) 1979-02-27
BG28417A3 (en) 1980-04-15
PL108916B1 (en) 1980-05-31

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