DK484584A - Oestran- og androstanderivater, fremgangsmaade til deres fremstilling og praeparater indeholdende disse forbindelser - Google Patents
Oestran- og androstanderivater, fremgangsmaade til deres fremstilling og praeparater indeholdende disse forbindelser Download PDFInfo
- Publication number
- DK484584A DK484584A DK484584A DK484584A DK484584A DK 484584 A DK484584 A DK 484584A DK 484584 A DK484584 A DK 484584A DK 484584 A DK484584 A DK 484584A DK 484584 A DK484584 A DK 484584A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- carbon
- derivatives
- hydrogen
- carbon atoms
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000004043 oxo group Chemical group O=* 0.000 abstract 3
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 2
- GRXPVLPQNMUNNX-MHJRRCNVSA-N estrane Chemical compound C1CC2CCCC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 GRXPVLPQNMUNNX-MHJRRCNVSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- -1 1,3-propylene group Chemical group 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 150000001440 androstane derivatives Chemical class 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 125000004980 cyclopropylene group Chemical group 0.000 abstract 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- SBXWFLISHPUINY-UHFFFAOYSA-N triphenyltin Chemical group C1=CC=CC=C1[Sn](C=1C=CC=CC=1)C1=CC=CC=C1 SBXWFLISHPUINY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3337179A DE3337179A1 (de) | 1983-10-10 | 1983-10-10 | Estran- und androstan-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende praeparate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK484584D0 DK484584D0 (da) | 1984-10-10 |
| DK484584A true DK484584A (da) | 1985-04-11 |
Family
ID=6211683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK484584A DK484584A (da) | 1983-10-10 | 1984-10-10 | Oestran- og androstanderivater, fremgangsmaade til deres fremstilling og praeparater indeholdende disse forbindelser |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4945064A (es) |
| EP (1) | EP0137434B1 (es) |
| JP (1) | JPH0635476B2 (es) |
| AT (1) | ATE72247T1 (es) |
| AU (1) | AU3406684A (es) |
| CA (1) | CA1300601C (es) |
| DE (2) | DE3337179A1 (es) |
| DK (1) | DK484584A (es) |
| ES (1) | ES8506326A1 (es) |
| GR (1) | GR80583B (es) |
| IE (1) | IE58642B1 (es) |
| NZ (1) | NZ209811A (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3427795A1 (de) * | 1984-07-25 | 1986-02-06 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue 17(alpha)-halogenvinyl-estran-derivate, ihre herstellung und verwendung in der medizin |
| IE58562B1 (en) * | 1985-07-24 | 1993-10-06 | Akzo Nv | Novel 11-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions |
| US4780420A (en) * | 1985-09-30 | 1988-10-25 | Yale University | Progesterone receptor ligands |
| DE3627154A1 (de) * | 1986-08-11 | 1988-02-25 | Schering Ag | Verfahren zur herstellung von (z)-17(alpha)-halogenvinyl-steroiden und (z)-17(alpha)-chlorvinyl-steroide |
| JPH01500903A (ja) * | 1986-08-11 | 1989-03-30 | シエーリング アクチエンゲゼルシヤフト | (Z)‐17α‐ハロゲンビニル‐ステロイドの製造法 |
| FR2613937B1 (fr) * | 1987-04-17 | 1989-07-21 | Ire Celltarg Sa | Ligands specifiques de recepteurs d'hormones steroides utiles pour la therapie ciblee ou l'imagerie medicale notamment du cancer |
| FR2637803B1 (fr) * | 1988-10-19 | 1993-07-09 | Ire Celltarg Sa | Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese |
| US5427766A (en) * | 1993-11-15 | 1995-06-27 | The Dow Chemical Company | Radiolabeled steroids for use in radiochemical-guided surgery |
| PL356465A1 (en) * | 2002-10-04 | 2004-04-05 | ANPHARM Przedsiębiorstwo Farmaceutyczne S.A. | METHOD OF MANUFACTURE OF 17beta-HYDROXY-7alpha-METHYL-19-NOR-17alpha-PREGN-5(10)-ENE-20-YNE-3-ONE |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3498975A (en) * | 1960-09-30 | 1970-03-03 | Merck & Co Inc | Haloethisterone compounds |
| US3498978A (en) * | 1967-04-10 | 1970-03-03 | Geigy Chem Corp | 3-pipecoline derivatives |
| US4321208A (en) * | 1976-09-27 | 1982-03-23 | Velayudhan Sahadevan | Preparation of directly iodinated steroid hormones and related compounds |
| US4541957A (en) * | 1983-09-07 | 1985-09-17 | The George Washington University | Process for preparing iodovinyl-estradiol |
-
1983
- 1983-10-10 DE DE3337179A patent/DE3337179A1/de not_active Withdrawn
-
1984
- 1984-09-29 DE DE8484111685T patent/DE3485490D1/de not_active Expired - Lifetime
- 1984-09-29 AT AT84111685T patent/ATE72247T1/de not_active IP Right Cessation
- 1984-09-29 EP EP84111685A patent/EP0137434B1/de not_active Expired - Lifetime
- 1984-10-08 NZ NZ209811A patent/NZ209811A/en unknown
- 1984-10-09 AU AU34066/84A patent/AU3406684A/en not_active Abandoned
- 1984-10-09 CA CA000464960A patent/CA1300601C/en not_active Expired - Lifetime
- 1984-10-09 IE IE257584A patent/IE58642B1/en not_active IP Right Cessation
- 1984-10-09 GR GR80583A patent/GR80583B/el unknown
- 1984-10-10 ES ES536649A patent/ES8506326A1/es not_active Expired
- 1984-10-10 DK DK484584A patent/DK484584A/da not_active Application Discontinuation
- 1984-10-11 JP JP59211601A patent/JPH0635476B2/ja not_active Expired - Lifetime
-
1988
- 1988-01-19 US US07/147,580 patent/US4945064A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1300601C (en) | 1992-05-12 |
| ATE72247T1 (de) | 1992-02-15 |
| DE3337179A1 (de) | 1985-05-23 |
| US4945064A (en) | 1990-07-31 |
| NZ209811A (en) | 1988-02-29 |
| AU3406684A (en) | 1986-09-11 |
| DK484584D0 (da) | 1984-10-10 |
| JPH0635476B2 (ja) | 1994-05-11 |
| EP0137434B1 (de) | 1992-01-29 |
| IE58642B1 (en) | 1993-10-20 |
| EP0137434A2 (de) | 1985-04-17 |
| ES536649A0 (es) | 1985-07-16 |
| IE842575L (en) | 1985-04-10 |
| DE3485490D1 (de) | 1992-03-12 |
| GR80583B (en) | 1985-02-04 |
| EP0137434A3 (en) | 1986-01-08 |
| JPS60155193A (ja) | 1985-08-15 |
| ES8506326A1 (es) | 1985-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |