DK477178A - Fremgangsmaade til fremstilling af derivater af bpti (basic pancreatic trypsin inhibitor). - Google Patents

Fremgangsmaade til fremstilling af derivater af bpti (basic pancreatic trypsin inhibitor).

Info

Publication number
DK477178A
DK477178A DK477178A DK477178A DK477178A DK 477178 A DK477178 A DK 477178A DK 477178 A DK477178 A DK 477178A DK 477178 A DK477178 A DK 477178A DK 477178 A DK477178 A DK 477178A
Authority
DK
Denmark
Prior art keywords
bpasi
derivatives
preparing
procedure
trypsin inhibitor
Prior art date
Application number
DK477178A
Other languages
English (en)
Inventor
E Schnabel
G Reinhardt
H D Schlumberger
H G Opitz
E Truscheit
H Tschesche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK477178A publication Critical patent/DK477178A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK477178A 1977-10-27 1978-10-26 Fremgangsmaade til fremstilling af derivater af bpti (basic pancreatic trypsin inhibitor). DK477178A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772748295 DE2748295A1 (de) 1977-10-27 1977-10-27 Neue derivate des bpti

Publications (1)

Publication Number Publication Date
DK477178A true DK477178A (da) 1979-04-28

Family

ID=6022457

Family Applications (1)

Application Number Title Priority Date Filing Date
DK477178A DK477178A (da) 1977-10-27 1978-10-26 Fremgangsmaade til fremstilling af derivater af bpti (basic pancreatic trypsin inhibitor).

Country Status (6)

Country Link
EP (1) EP0001774A1 (da)
JP (1) JPS5473702A (da)
DE (1) DE2748295A1 (da)
DK (1) DK477178A (da)
ES (1) ES474559A1 (da)
IT (1) IT7829122A0 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3135541A1 (de) * 1981-09-08 1983-03-24 Bayer Ag, 5090 Leverkusen Kallikrein-trypsin-inhibitor-(bpti)-derivate, traegergebundene bpti-derivate, ihre herstellung und ihre verwendung zur herstellung der reinen enzyme trypsin, chymotrypsin und kallikrein
JPS5921656A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd ポリペプチド誘導体
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
WO2007099650A1 (en) * 2006-03-01 2007-09-07 Fukuoka Prefectural Government Peptide lipid-containing carrier and method for introducing compound into cells using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4729807U (da) * 1971-04-26 1972-12-05
JPS5139212Y2 (da) * 1973-02-24 1976-09-25
DE2619246A1 (de) * 1976-04-30 1977-11-10 Bayer Ag Desamino-derivate des kallikrein- trypsin-inhibitors, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2654124A1 (de) * 1976-11-29 1978-06-01 Bayer Ag Derivate des trypsin-kallikrein-inhibitors aus rinderorganen (bpti) mit proteasenhemmwirkung und antiphlogistischer wirkung, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
IT7829122A0 (it) 1978-10-25
ES474559A1 (es) 1979-10-16
EP0001774A1 (de) 1979-05-16
JPS5473702A (en) 1979-06-13
DE2748295A1 (de) 1979-05-03

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DK477178A (da) Fremgangsmaade til fremstilling af derivater af bpti (basic pancreatic trypsin inhibitor).