DK474782A - Inklusionskomplekser af steroider med gamma-cyclodextrin, deres fremstilling og anvendelse - Google Patents

Inklusionskomplekser af steroider med gamma-cyclodextrin, deres fremstilling og anvendelse Download PDF

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Publication number
DK474782A
DK474782A DK474782A DK474782A DK474782A DK 474782 A DK474782 A DK 474782A DK 474782 A DK474782 A DK 474782A DK 474782 A DK474782 A DK 474782A DK 474782 A DK474782 A DK 474782A
Authority
DK
Denmark
Prior art keywords
steroids
preparation
gamma cyclodextrin
inclusion complexs
complexs
Prior art date
Application number
DK474782A
Other languages
English (en)
Inventor
Agnes Stadler
Jozsef Szejtli
Ilona Habon
Gyozo Hortobagyi
Ilona Kolbe
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK474782A publication Critical patent/DK474782A/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK474782A 1981-10-27 1982-10-26 Inklusionskomplekser af steroider med gamma-cyclodextrin, deres fremstilling og anvendelse DK474782A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU813147A HU190356B (en) 1981-10-27 1981-10-27 Process for preparing steroid-gamma-cyclodextrin inclusion complexes with high water-solubility

Publications (1)

Publication Number Publication Date
DK474782A true DK474782A (da) 1983-04-28

Family

ID=10962794

Family Applications (1)

Application Number Title Priority Date Filing Date
DK474782A DK474782A (da) 1981-10-27 1982-10-26 Inklusionskomplekser af steroider med gamma-cyclodextrin, deres fremstilling og anvendelse

Country Status (12)

Country Link
JP (1) JPS5883699A (da)
BE (1) BE894825A (da)
DD (1) DD208549A5 (da)
DE (1) DE3238800A1 (da)
DK (1) DK474782A (da)
ES (1) ES8308571A1 (da)
FR (1) FR2515187A1 (da)
GB (1) GB2109381A (da)
HU (1) HU190356B (da)
IT (1) IT1191049B (da)
NL (1) NL8204122A (da)
SE (1) SE8206055L (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196230B (en) * 1983-12-29 1988-10-28 Chinoin Gyogyszer Es Vegyeszet Process for producing water-soluble forms of polyene antibiotics and pharmaceutics comprising such active ingredient and plant protective with antifungal effect
GB2162529B (en) * 1984-06-08 1988-03-02 Nitrokemia Ipartelepek B-cyclodextrin complex of benzene sulphonyl urea derivatives
US5223295A (en) * 1988-01-22 1993-06-29 Asterol International Process for the elimination of steroid compounds contained in substance of biological origin
EP0381747A4 (en) * 1988-08-15 1991-09-11 American Maize-Products Company Water soluble branched beta cyclodextrin steroid complex
US5229370A (en) * 1988-08-15 1993-07-20 Ammeraal Robert N Water soluble branched beta cyclodextrin steroid complex
CA2087452A1 (en) * 1991-05-20 1992-11-21 Toshiro Tsuda Steriod compound combined with polysaccharide
US20040152664A1 (en) * 1998-09-02 2004-08-05 Allergan, Inc. Prednisolone compositions
WO2002036105A2 (en) * 2000-11-02 2002-05-10 Akzo Nobel N.V. Use of cortisol-sequestering agents for the treatment of hypercortisolaemia related disorders
EP1216713A1 (en) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
EP1216712A1 (en) * 2000-12-20 2002-06-26 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
AU2002222387A1 (en) * 2000-12-20 2002-07-01 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
US20070020298A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US20150031532A1 (en) * 2012-03-13 2015-01-29 Amphidex A/S Production Of Stabilized Channel Type Cyclodextrin Crystals

Also Published As

Publication number Publication date
ES516840A0 (es) 1983-09-16
ES8308571A1 (es) 1983-09-16
NL8204122A (nl) 1983-05-16
JPS5883699A (ja) 1983-05-19
IT8223942A0 (it) 1982-10-26
SE8206055D0 (sv) 1982-10-25
HU190356B (en) 1986-08-28
FR2515187A1 (fr) 1983-04-29
DE3238800A1 (de) 1983-05-05
GB2109381A (en) 1983-06-02
SE8206055L (sv) 1983-04-28
DD208549A5 (de) 1984-04-04
IT1191049B (it) 1988-02-24
BE894825A (fr) 1983-02-14

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