DK470687D0 - Phenyl, pyrrolidin-2-yl substituerede 5-ring heterocycliske forbindelser med antipsykotiske egenskaber - Google Patents
Phenyl, pyrrolidin-2-yl substituerede 5-ring heterocycliske forbindelser med antipsykotiske egenskaberInfo
- Publication number
- DK470687D0 DK470687D0 DK470687A DK470687A DK470687D0 DK 470687 D0 DK470687 D0 DK 470687D0 DK 470687 A DK470687 A DK 470687A DK 470687 A DK470687 A DK 470687A DK 470687 D0 DK470687 D0 DK 470687D0
- Authority
- DK
- Denmark
- Prior art keywords
- phenyl
- pyrrolidin
- substituted
- heterocyclic compounds
- properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8602305 | 1986-09-12 | ||
NL8602305 | 1986-09-12 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK470687D0 true DK470687D0 (da) | 1987-09-09 |
DK470687A DK470687A (da) | 1988-03-13 |
DK166275B DK166275B (da) | 1993-03-29 |
DK166275C DK166275C (da) | 1993-08-23 |
Family
ID=19848538
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK470687A DK166275C (da) | 1986-09-12 | 1987-09-09 | Derivater af phenyl, pyrrolidin-2-yl substitueret pyrrol og farmaceutisk acceptable syreadditionssalte heraf med antipsykotiske egenskaber, fremgangsmaade til fremstilling heraf, samt farmaceutiske praeparater indeholdende disse forbindelser |
Country Status (14)
Country | Link |
---|---|
US (1) | US4791132A (da) |
EP (1) | EP0259930B1 (da) |
JP (1) | JPH0794432B2 (da) |
AT (1) | ATE72435T1 (da) |
AU (1) | AU609415B2 (da) |
DE (1) | DE3776611D1 (da) |
DK (1) | DK166275C (da) |
ES (1) | ES2033297T3 (da) |
GR (1) | GR3004436T3 (da) |
IE (1) | IE60294B1 (da) |
IL (1) | IL83841A (da) |
NZ (1) | NZ221731A (da) |
PH (1) | PH23898A (da) |
ZA (1) | ZA876749B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4992441A (en) * | 1987-10-14 | 1991-02-12 | Mcneilab, Inc. | 1-[[5-[[4-substituted-1-piperazinyl]methyl]-pyrrol-2-yl or furan-2-yl]methyl-2-piperidinones useful in treating schizophrenia |
US5523299A (en) * | 1992-08-06 | 1996-06-04 | Smithkline Beecham Plc | 5-(2-oxyphenyl)-pyrrole derivatives as dopamine D3 receptor antagonists |
GB9307400D0 (en) * | 1993-04-08 | 1993-06-02 | Smithkline Beecham Plc | Compounds |
GB9309573D0 (en) * | 1993-05-10 | 1993-06-23 | Merck Sharp & Dohme | Therapeutic agents |
WO1995000508A1 (en) * | 1993-06-25 | 1995-01-05 | Smithkline Beecham Plc | Phenyrrole derivatives and their use as dopamine d3 antagonists |
GB9315800D0 (en) * | 1993-07-30 | 1993-09-15 | Smithkline Beecham Plc | Compounds |
GB9315801D0 (en) * | 1993-07-30 | 1993-09-15 | Smithkline Beecham Plc | Compounds |
GB9320855D0 (en) * | 1993-10-09 | 1993-12-01 | Smithkline Beecham Plc | Compounds |
GB9402197D0 (en) * | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Compounds |
GB9403199D0 (en) * | 1994-02-19 | 1994-04-13 | Smithkline Beecham Plc | Compounds |
GB9512129D0 (en) * | 1995-06-15 | 1995-08-16 | Smithkline Beecham Plc | Compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4219560A (en) * | 1978-04-17 | 1980-08-26 | Sandoz, Inc. | Piperidine and pyrrolidine alcohols |
DE2835439A1 (de) * | 1978-08-12 | 1980-02-28 | Basf Ag | 2-(o-hydroxyphenyl)-pyrrol |
US4321385A (en) * | 1980-02-04 | 1982-03-23 | Hoechst Roussel Pharmaceuticals Inc. | [(Aryl-1-pyrryl) methyl]-piperidinols and pyrrolidinols |
US4539332A (en) * | 1983-11-14 | 1985-09-03 | Merck & Co., Inc. | 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists |
-
1987
- 1987-09-08 PH PH35780A patent/PH23898A/en unknown
- 1987-09-09 IE IE240987A patent/IE60294B1/en not_active IP Right Cessation
- 1987-09-09 NZ NZ221731A patent/NZ221731A/xx unknown
- 1987-09-09 AT AT87201706T patent/ATE72435T1/de not_active IP Right Cessation
- 1987-09-09 ES ES198787201706T patent/ES2033297T3/es not_active Expired - Lifetime
- 1987-09-09 DK DK470687A patent/DK166275C/da active
- 1987-09-09 DE DE8787201706T patent/DE3776611D1/de not_active Expired - Fee Related
- 1987-09-09 ZA ZA876749A patent/ZA876749B/xx unknown
- 1987-09-09 US US07/094,746 patent/US4791132A/en not_active Expired - Fee Related
- 1987-09-09 EP EP87201706A patent/EP0259930B1/en not_active Expired - Lifetime
- 1987-09-09 IL IL83841A patent/IL83841A/xx not_active IP Right Cessation
- 1987-09-09 AU AU78191/87A patent/AU609415B2/en not_active Ceased
- 1987-09-10 JP JP62225427A patent/JPH0794432B2/ja not_active Expired - Lifetime
-
1992
- 1992-04-22 GR GR920400808T patent/GR3004436T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PH23898A (en) | 1989-12-18 |
GR3004436T3 (da) | 1993-03-31 |
DK166275C (da) | 1993-08-23 |
JPS6377856A (ja) | 1988-04-08 |
ZA876749B (en) | 1988-03-14 |
US4791132A (en) | 1988-12-13 |
DK470687A (da) | 1988-03-13 |
EP0259930A1 (en) | 1988-03-16 |
EP0259930B1 (en) | 1992-02-05 |
AU7819187A (en) | 1988-03-17 |
NZ221731A (en) | 1990-07-26 |
AU609415B2 (en) | 1991-05-02 |
ES2033297T3 (es) | 1993-03-16 |
IL83841A (en) | 1991-11-21 |
DK166275B (da) | 1993-03-29 |
ATE72435T1 (de) | 1992-02-15 |
IE60294B1 (en) | 1994-06-29 |
IL83841A0 (en) | 1988-02-29 |
IE872409L (en) | 1988-03-12 |
JPH0794432B2 (ja) | 1995-10-11 |
DE3776611D1 (de) | 1992-03-19 |
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