DK461389A - Quinolyloxazol-2-oner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse - Google Patents

Quinolyloxazol-2-oner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse Download PDF

Info

Publication number
DK461389A
DK461389A DK461389A DK461389A DK461389A DK 461389 A DK461389 A DK 461389A DK 461389 A DK461389 A DK 461389A DK 461389 A DK461389 A DK 461389A DK 461389 A DK461389 A DK 461389A
Authority
DK
Denmark
Prior art keywords
quinolyloxazol
ones
preparation
acceptable salts
pharmaceutical acceptable
Prior art date
Application number
DK461389A
Other languages
Danish (da)
English (en)
Other versions
DK461389D0 (da
Inventor
Winton Dennis Jones
Richard Cyrus Dage
George Philip Claxton
Hsien Chang Cheng
Phillip James Robinson
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK461389D0 publication Critical patent/DK461389D0/da
Publication of DK461389A publication Critical patent/DK461389A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
DK461389A 1988-10-24 1989-09-19 Quinolyloxazol-2-oner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse DK461389A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/261,435 US4886811A (en) 1988-10-24 1988-10-24 Qunolyloxazole-2-ones useful as proteinkinase C inhibitors

Publications (2)

Publication Number Publication Date
DK461389D0 DK461389D0 (da) 1989-09-19
DK461389A true DK461389A (da) 1990-04-25

Family

ID=22993289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK461389A DK461389A (da) 1988-10-24 1989-09-19 Quinolyloxazol-2-oner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse

Country Status (21)

Country Link
US (1) US4886811A (sv)
EP (1) EP0365863B1 (sv)
JP (2) JP2879454B2 (sv)
KR (1) KR0162637B1 (sv)
CN (1) CN1025854C (sv)
AR (1) AR246733A1 (sv)
AT (1) ATE110074T1 (sv)
AU (1) AU613302B2 (sv)
CA (1) CA2000804C (sv)
DE (1) DE68917556T2 (sv)
DK (1) DK461389A (sv)
ES (1) ES2061863T3 (sv)
FI (1) FI93112C (sv)
HU (1) HUT58088A (sv)
IE (1) IE893011L (sv)
IL (1) IL91788A (sv)
NO (1) NO894210L (sv)
NZ (1) NZ230718A (sv)
PH (1) PH27450A (sv)
PT (1) PT91870B (sv)
ZA (1) ZA897259B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036093A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
DE3907414A1 (de) * 1989-03-08 1990-09-13 Hoechst Ag Die anwendung inhalierter schleifendiuretika zur behandlung von allergen-induzierten nasalen reaktionen
US5190957A (en) * 1989-11-13 1993-03-02 Merrell Dow Pharmaceuticals Inc. Treatment of multi-drug resistant tumors with quinolyl-and isoquinolyloxazole-2-ones
PH27309A (en) * 1989-11-13 1993-05-28 Merrell Dow Pharma Prevention of glycoprotein enveloped virus infectivity by quinolyl-and isoquinolyloxazone-2-ones
ZA908936B (en) * 1989-11-13 1991-09-25 Merrell Dow Pharma Treatment of multi-drug resistant tumors with quinolyloxazole-2-ones
US5182293A (en) * 1989-11-13 1993-01-26 Merrell Dow Pharmaceuticals Inc. Treatment of multi-drug resistant tumors with pyridyloxazole-2-ones
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
DE69435137D1 (de) * 1993-05-13 2008-10-16 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
GB9819382D0 (en) 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I
GB9929216D0 (en) * 1999-12-11 2000-02-02 Univ Bristol Isoquinoline and Quinoline Containing substances
WO2006130090A1 (en) * 2005-06-03 2006-12-07 Pronas Pharma Ab Use of a substance which inhibits endothelin type b and 5-hydroxytryptamine type 1b receptor upregulation in the treatment of ischemic disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3025215A (en) * 1959-07-29 1962-03-13 Monsanto Chemicals Bis (8-quinolyl carbonate) derivatives
US3857877A (en) * 1973-01-12 1974-12-31 Karamchand Premchand Private 8-hydroxy quinoline derivatives
US4565820A (en) * 1980-07-28 1986-01-21 Pfizer Inc. Hypoglycemic 5-pyrrolyl, indolyl and quinolyl substituted oxazolidine-2,4-diones and their use
GB8505492D0 (en) * 1985-03-04 1985-04-03 Roussel Lab Ltd Chemical compounds
US4738972A (en) * 1985-05-21 1988-04-19 Pfizer Inc. Hypoglycemic thiazolidinediones
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
US4670450A (en) * 1985-11-13 1987-06-02 Merrell Dow Pharmaceuticals Inc. Cardiotonic thiazolones
US4698353A (en) * 1985-11-13 1987-10-06 Merrell Dow Pharmaceuticals Inc. Cardiotonic heterocyclic oxazolones
US4728661A (en) * 1985-11-13 1988-03-01 Merrell Dow Pharmaceuticals Inc. Cardiotonic phenyl oxazolones
US4681940A (en) * 1985-11-19 1987-07-21 American Home Products Corporation 5-[3-[[2-quinolyl]methoxy]phenyl]-1,3-oxazoles

Also Published As

Publication number Publication date
PT91870A (pt) 1990-04-30
DE68917556D1 (de) 1994-09-22
FI894459A (sv) 1990-04-25
ZA897259B (en) 1990-07-25
PH27450A (en) 1993-07-02
EP0365863A3 (en) 1990-11-07
IE893011L (en) 1990-04-24
ES2061863T3 (es) 1994-12-16
FI894459A0 (sv) 1989-09-20
EP0365863A2 (en) 1990-05-02
IL91788A (en) 1994-04-12
EP0365863B1 (en) 1994-08-17
IL91788A0 (en) 1990-06-10
NZ230718A (en) 1990-11-27
PT91870B (pt) 1995-05-31
JP2879454B2 (ja) 1999-04-05
AU613302B2 (en) 1991-07-25
KR900006307A (ko) 1990-05-07
ATE110074T1 (de) 1994-09-15
CA2000804A1 (en) 1990-04-24
DE68917556T2 (de) 1994-12-15
US4886811A (en) 1989-12-12
JP2983970B2 (ja) 1999-11-29
NO894210L (no) 1990-04-25
JPH02164878A (ja) 1990-06-25
DK461389D0 (da) 1989-09-19
JPH11152285A (ja) 1999-06-08
CN1042145A (zh) 1990-05-16
FI93112C (sv) 1995-02-27
NO894210D0 (no) 1989-10-23
FI93112B (sv) 1994-11-15
KR0162637B1 (ko) 1998-12-01
AR246733A1 (es) 1994-09-30
CA2000804C (en) 1999-04-06
AU4249389A (en) 1990-04-26
CN1025854C (zh) 1994-09-07
HUT58088A (en) 1992-01-28
HU895410D0 (en) 1990-01-28

Similar Documents

Publication Publication Date Title
NO924650D0 (no) Dialkoksy-pyridinyl-benzimidazolderivater, fremgangsmaate for deres fremstilling og deres farmasoeytiske anvendelse
DK374389D0 (da) Arylbenzenoxazolidinoner, deres fremstilling og anvendelse
DK609489D0 (da) Imidazolderivater, deres fremstilling og anvendelse
DK434488D0 (da) Heteroarylethere og heteroaromatiske n-oxider eller farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse
DK519189A (da) Spiro-isoquinolin-pyrrolidin-tetroner eller farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse
DK374289D0 (da) Indazol-3-carboxylsyrederivater, deres fremstilling og anvendelse
DK605489A (da) Beta-amino-boronsyre-derivater, deres fremstilling og anvendelse
DK209188D0 (da) Bifunktionelle proteiner, deres fremstilling og anvendelse som laegemiddel
DK461389A (da) Quinolyloxazol-2-oner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse
DK388989A (da) Acylcyanoguanidiner, deres fremstilling og anvendelse
DK435289D0 (da) Piperazindioner, deres fremstilling og anvendelse
DK69389D0 (da) Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse
DK543788D0 (da) Reninhaemmende dipeptider eller fysiologisk acceptable salte deraf, deres fremstilling og anvendelse
DK225089D0 (da) 2-adamantyl-4-isothiazolin-3-oner, deres fremstilling og anvendelse
DK469389A (da) Piperidinyl-imidazol-derivater, deres fremstilling og anvendelse
DK196389A (da) N-substituerede n-amino-pyrroler, deres fremstilling og anvendelse
DK47788D0 (da) 14,15-substituerede lanosteroler og fysiologisk acceptable salte deraf og deres anvendelse som farmaceutika
DK592389D0 (da) Penemderivater, deres fremstilling og anvendelse
DK530388D0 (da) Pyrrolo-(1,2-b)cinnoliner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse
DK404386D0 (da) Spergualinbeslaegtede forbindelser eller fysiologisk acceptable salte deraf, deres fremstilling og anvendelse
DK514786D0 (da) 5-heterocyclyl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner og tautomere og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelsesom antidepressive midler
DK602389D0 (da) Benzensulfonamidderivater, deres fremstilling og anvendelse
DK163589D0 (da) Sakyomycin e og derivater deraf, deres fremstilling og anvendelse
DK258289D0 (da) Imidazoquinoxalin forbindelser, deres fremstilling og anvendelse
DK142288D0 (da) Quinoxalinforbindelser, deres fremstilling og anvendelse

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment