DK440486A - Antipsykotiske gamma-carboliner - Google Patents

Antipsykotiske gamma-carboliner Download PDF

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Publication number
DK440486A
DK440486A DK440486A DK440486A DK440486A DK 440486 A DK440486 A DK 440486A DK 440486 A DK440486 A DK 440486A DK 440486 A DK440486 A DK 440486A DK 440486 A DK440486 A DK 440486A
Authority
DK
Denmark
Prior art keywords
sup
alkyl
hydrogen
cycotic
halogen
Prior art date
Application number
DK440486A
Other languages
Danish (da)
English (en)
Other versions
DK440486D0 (da
Inventor
Magid Abdel-Megid Abou-Gharbia
Usha Rajni Patel
Reinhardt Peter Stein
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of DK440486D0 publication Critical patent/DK440486D0/da
Publication of DK440486A publication Critical patent/DK440486A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK440486A 1985-09-16 1986-09-15 Antipsykotiske gamma-carboliner DK440486A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,349 US4672117A (en) 1985-09-16 1985-09-16 Antipsychotic gamma-carbolines

Publications (2)

Publication Number Publication Date
DK440486D0 DK440486D0 (da) 1986-09-15
DK440486A true DK440486A (da) 1987-03-17

Family

ID=25107141

Family Applications (1)

Application Number Title Priority Date Filing Date
DK440486A DK440486A (da) 1985-09-16 1986-09-15 Antipsykotiske gamma-carboliner

Country Status (15)

Country Link
US (1) US4672117A (de)
EP (1) EP0222474B1 (de)
JP (1) JPS6270374A (de)
KR (1) KR900002246B1 (de)
AT (1) ATE57184T1 (de)
AU (1) AU583941B2 (de)
CA (1) CA1275100A (de)
DE (1) DE3674721D1 (de)
DK (1) DK440486A (de)
ES (1) ES2002617A6 (de)
GB (1) GB2180535B (de)
GR (1) GR862344B (de)
HU (1) HU194564B (de)
PT (1) PT83345B (de)
ZA (1) ZA866259B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636563A (en) * 1985-09-16 1987-01-13 American Home Products Corporation Antipsychotic γ-carbolines
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
EP0620222A3 (de) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-betacarboline.
WO1995018092A1 (fr) * 1993-12-28 1995-07-06 Maruho Co., Ltd. Derive de l'aminocetone
EP0905136A1 (de) * 1997-09-08 1999-03-31 Janssen Pharmaceutica N.V. Tetrahydro gamma-Carboline
JP2004015286A (ja) * 2002-06-05 2004-01-15 Seiko Epson Corp ディジタルカメラ
EP1757605A4 (de) * 2004-04-12 2007-12-19 Taisho Pharmaceutical Co Ltd Cyclische aminverbindung
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
BRPI0815850A2 (pt) * 2007-08-01 2014-10-07 Medivation Neurology Inc "método para tratar, retardar a progressão, prevenir ou atrasar o desenvolvimento de esquizofrenia em um individuo, composiçã farmaceuticamente aceitável, kit e método para reforçar uma resposta de um individuo a um antipsicótico"

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522262A (en) * 1968-09-10 1970-07-28 Hoffmann La Roche 5-(pyridylalkyl)-pyridoindole derivatives
US3502688A (en) * 1968-09-10 1970-03-24 Hoffmann La Roche 5-(4-pyridylethyl)-pyridoindole derivatives
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
DE3851597T2 (de) * 1987-09-03 1995-01-26 Glaxo Group Ltd., London Lactamderivate.

Also Published As

Publication number Publication date
GB8621225D0 (en) 1986-10-08
HUT42480A (en) 1987-07-28
GR862344B (en) 1987-01-12
GB2180535A (en) 1987-04-01
KR870003104A (ko) 1987-04-15
PT83345A (pt) 1986-10-01
US4672117A (en) 1987-06-09
AU6181486A (en) 1987-03-19
EP0222474A1 (de) 1987-05-20
PT83345B (pt) 1988-07-29
HU194564B (en) 1988-02-29
JPS6270374A (ja) 1987-03-31
ATE57184T1 (de) 1990-10-15
DE3674721D1 (en) 1990-11-08
ES2002617A6 (es) 1988-09-01
EP0222474B1 (de) 1990-10-03
DK440486D0 (da) 1986-09-15
CA1275100A (en) 1990-10-09
GB2180535B (en) 1989-04-05
ZA866259B (en) 1988-03-30
KR900002246B1 (ko) 1990-04-07
AU583941B2 (en) 1989-05-11

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Legal Events

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AHB Application shelved due to non-payment