DK437588A - Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydroisoquinolin til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater - Google Patents
Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydroisoquinolin til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivaterInfo
- Publication number
- DK437588A DK437588A DK437588A DK437588A DK437588A DK 437588 A DK437588 A DK 437588A DK 437588 A DK437588 A DK 437588A DK 437588 A DK437588 A DK 437588A DK 437588 A DK437588 A DK 437588A
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- tetrahydroisoquinoline
- piperidinyl
- methyl
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8711288A FR2619110B1 (fr) | 1987-08-07 | 1987-08-07 | Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
FR8718342A FR2625504B2 (fr) | 1987-08-07 | 1987-12-30 | Derives de ((benzoyl-1 piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
FR8805130A FR2630114B2 (fr) | 1987-08-07 | 1988-04-19 | Derives de (piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
FR8805129A FR2630113B2 (fr) | 1987-08-07 | 1988-04-19 | Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
DK437588D0 DK437588D0 (da) | 1988-08-05 |
DK437588A true DK437588A (da) | 1989-03-28 |
Family
ID=27446582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK437588A DK437588A (da) | 1987-08-07 | 1988-08-05 | Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydroisoquinolin til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater |
Country Status (10)
Country | Link |
---|---|
US (2) | US4885302A (fi) |
EP (1) | EP0306375A1 (fi) |
JP (1) | JPH01100167A (fi) |
KR (1) | KR890003733A (fi) |
AU (1) | AU598149B2 (fi) |
DK (1) | DK437588A (fi) |
FI (1) | FI883667A (fi) |
IL (1) | IL87339A0 (fi) |
NO (1) | NO883485L (fi) |
NZ (1) | NZ225708A (fi) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3717561A1 (de) * | 1987-05-25 | 1988-12-08 | Thomae Gmbh Dr K | Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
IL89156A (en) * | 1988-07-12 | 1993-05-13 | Synthelabo | Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics |
US4963563A (en) * | 1989-10-13 | 1990-10-16 | Abbott Laboratories | 6-substituted-1,2,3,4-tetrahydroisoquinolines |
FR2661178B1 (fr) * | 1990-04-24 | 1993-03-12 | Synthelabo | Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique. |
US5258379A (en) * | 1990-05-04 | 1993-11-02 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with n-arylpiperazines |
US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
GB9319534D0 (en) * | 1993-09-22 | 1993-11-10 | Boots Co Plc | Therapeutic agents |
FR2747386B1 (fr) * | 1996-04-12 | 1998-05-15 | Synthelabo | Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique |
JP2000512646A (ja) * | 1996-06-25 | 2000-09-26 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 5ht7受容体アンタゴニストとしてのスルホンアミド誘導体 |
US5912342A (en) * | 1997-08-12 | 1999-06-15 | Heinonen; Petri | Compounds a containing a solid support |
US6664293B2 (en) | 1999-02-26 | 2003-12-16 | Fujiwawa Pharmaceutical Co., Ltd. | Amide compounds for the potentiation of cholinergic activity |
AUPP891299A0 (en) * | 1999-02-26 | 1999-03-25 | Fujisawa Pharmaceutical Co., Ltd. | New 6-membered cyclic compounds |
AR063275A1 (es) * | 2006-10-12 | 2009-01-14 | Epix Delaware Inc | Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2. |
WO2009076404A1 (en) * | 2007-12-10 | 2009-06-18 | Epix Delaware, Inc. | Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor |
WO2009076512A1 (en) * | 2007-12-11 | 2009-06-18 | Epix Delaware, Inc. | Carboxamidξ compounds and their use as chemokine receptor agonists |
PL2445899T3 (pl) | 2009-06-26 | 2017-08-31 | Sanofi | Nowe sole fumaranowe antagonisty receptora histaminy H3 |
CN117157069A (zh) * | 2021-02-12 | 2023-12-01 | 康复治疗公司 | 用于调节fgf活性的化合物、组合物和方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2922786A (en) * | 1956-12-12 | 1960-01-26 | Bristol Myers Co | Therapeutic compounds |
GB1229651A (fi) * | 1967-03-14 | 1971-04-28 | ||
FR7607M (fi) * | 1968-04-25 | 1970-01-19 | ||
GB1250719A (fi) * | 1969-03-19 | 1971-10-20 | ||
FR2426046A1 (fr) * | 1978-05-18 | 1979-12-14 | Synthelabo | Derive de tetrahydro-isoquinoleine, sa preparation et son application en therapeutique |
US4495354A (en) * | 1982-03-29 | 1985-01-22 | Hoffmann-La Roche Inc. | Process for bicyclic diketones |
IL89156A (en) * | 1988-07-12 | 1993-05-13 | Synthelabo | Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics |
-
1988
- 1988-08-03 EP EP88402022A patent/EP0306375A1/fr not_active Withdrawn
- 1988-08-04 IL IL87339A patent/IL87339A0/xx unknown
- 1988-08-05 NZ NZ225708A patent/NZ225708A/en unknown
- 1988-08-05 AU AU20475/88A patent/AU598149B2/en not_active Ceased
- 1988-08-05 JP JP63197010A patent/JPH01100167A/ja active Pending
- 1988-08-05 DK DK437588A patent/DK437588A/da not_active Application Discontinuation
- 1988-08-05 FI FI883667A patent/FI883667A/fi not_active Application Discontinuation
- 1988-08-05 NO NO88883485A patent/NO883485L/no unknown
- 1988-08-05 US US07/228,748 patent/US4885302A/en not_active Expired - Fee Related
- 1988-08-05 KR KR1019880010015A patent/KR890003733A/ko not_active Application Discontinuation
-
1989
- 1989-08-30 US US07/400,811 patent/US4945096A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2047588A (en) | 1989-02-09 |
FI883667A (fi) | 1989-02-08 |
AU598149B2 (en) | 1990-06-14 |
IL87339A0 (en) | 1989-01-31 |
DK437588D0 (da) | 1988-08-05 |
NO883485D0 (no) | 1988-08-05 |
FI883667A0 (fi) | 1988-08-05 |
KR890003733A (ko) | 1989-04-17 |
US4945096A (en) | 1990-07-31 |
US4885302A (en) | 1989-12-05 |
JPH01100167A (ja) | 1989-04-18 |
NO883485L (no) | 1989-02-08 |
NZ225708A (en) | 1990-04-26 |
EP0306375A1 (fr) | 1989-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |