DK4124339T3 - Lægemiddeltilførselssystemer og fremgangsmåder til behandling af blærecancer med gemcitabin - Google Patents

Lægemiddeltilførselssystemer og fremgangsmåder til behandling af blærecancer med gemcitabin

Info

Publication number
DK4124339T3
DK4124339T3 DK22196596.5T DK22196596T DK4124339T3 DK 4124339 T3 DK4124339 T3 DK 4124339T3 DK 22196596 T DK22196596 T DK 22196596T DK 4124339 T3 DK4124339 T3 DK 4124339T3
Authority
DK
Denmark
Prior art keywords
gemcitabine
methods
drug delivery
delivery systems
bladder cancer
Prior art date
Application number
DK22196596.5T
Other languages
Danish (da)
English (en)
Inventor
Dennis Giesing
Heejin Lee
Karen Daniel
Original Assignee
Taris Biomedical Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taris Biomedical Llc filed Critical Taris Biomedical Llc
Application granted granted Critical
Publication of DK4124339T3 publication Critical patent/DK4124339T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nanotechnology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
DK22196596.5T 2014-03-06 2015-03-06 Lægemiddeltilførselssystemer og fremgangsmåder til behandling af blærecancer med gemcitabin DK4124339T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461949215P 2014-03-06 2014-03-06
EP15711373.9A EP3113782B1 (en) 2014-03-06 2015-03-06 Drug delivery systems and methods for treatment of bladder cancer with gemcitabine

Publications (1)

Publication Number Publication Date
DK4124339T3 true DK4124339T3 (da) 2025-10-13

Family

ID=52697553

Family Applications (2)

Application Number Title Priority Date Filing Date
DK22196596.5T DK4124339T3 (da) 2014-03-06 2015-03-06 Lægemiddeltilførselssystemer og fremgangsmåder til behandling af blærecancer med gemcitabin
DK15711373.9T DK3113782T3 (da) 2014-03-06 2015-03-06 Lægemiddelleveringssystemer og fremgangsmåder til behandling af blærekræft med gemcitabin

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK15711373.9T DK3113782T3 (da) 2014-03-06 2015-03-06 Lægemiddelleveringssystemer og fremgangsmåder til behandling af blærekræft med gemcitabin

Country Status (24)

Country Link
US (3) US20150250717A1 (OSRAM)
EP (2) EP3113782B1 (OSRAM)
JP (4) JP6901858B2 (OSRAM)
KR (1) KR102338079B1 (OSRAM)
CN (2) CN119950539A (OSRAM)
AU (4) AU2015226901B2 (OSRAM)
BR (1) BR112016020381A8 (OSRAM)
CA (1) CA2939979C (OSRAM)
DK (2) DK4124339T3 (OSRAM)
ES (1) ES2930435T3 (OSRAM)
FI (1) FI4124339T3 (OSRAM)
HR (2) HRP20251264T1 (OSRAM)
HU (1) HUE060704T2 (OSRAM)
IL (2) IL247347B2 (OSRAM)
LT (2) LT4124339T (OSRAM)
MX (1) MX2016011333A (OSRAM)
PL (2) PL4124339T3 (OSRAM)
PT (2) PT4124339T (OSRAM)
RS (2) RS67337B1 (OSRAM)
RU (1) RU2694902C1 (OSRAM)
SG (2) SG10202101978SA (OSRAM)
SI (1) SI4124339T1 (OSRAM)
SM (2) SMT202500385T1 (OSRAM)
WO (1) WO2015134911A1 (OSRAM)

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MX367070B (es) 2012-08-31 2019-08-05 Taris Biomedical Llc Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata.
CA2919215C (en) 2013-08-19 2022-11-29 Taris Biomedical Llc Multi-unit drug delivery devices and methods
MX2016011333A (es) * 2014-03-06 2016-12-07 Taris Biomedical Llc Sistemas de administracion de farmaco y metodo para el tratamiento de cancer de vejiga con gemcitabina.
IL262746B (en) * 2016-05-06 2022-09-01 Taris Biomedical Llc A method for treating urothelial cancer in the lower system
AU2018306299B2 (en) 2017-07-25 2024-08-08 Taris Biomedical Llc Methods of treating tumor metastasis
SG11202003950WA (en) * 2017-11-08 2020-05-28 Taris Biomedical Llc Methods of treatment and maintenance therapy for bladder cancer using gemcitabine
JP2021532155A (ja) 2018-08-01 2021-11-25 タリス バイオメディカル エルエルシー トロスピウムを使用した過活動膀胱の治療方法
EP4039279A4 (en) * 2019-10-03 2023-11-01 Seikagaku Corporation TRANSMUCOSAL MEDICINAL ACTIVE DELIVERY SYSTEM FOR THE BLADDER SUBMUCOSA
RU2713443C2 (ru) * 2019-11-01 2020-02-05 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) Способ комбинированного лечения мышечно-инвазивного рака мочевого пузыря т3-т4 n0-+m0
EP4096686A4 (en) * 2020-01-27 2024-01-10 Isola Therapeutics, Inc. TISSUE DOSAGE FOR LOCAL INTRALUMINAL DRUG ADMINISTRATION
CN112169066B (zh) * 2020-10-29 2023-05-12 安徽省立医院(中国科学技术大学附属第一医院) 具有控制器的连续缓释给药留置管
CN113616666A (zh) * 2021-08-24 2021-11-09 傅广波 膀胱黏膜下注射吉西他滨在治疗膀胱癌中的应用

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US4111203A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
AU2003278881A1 (en) * 2002-09-23 2004-04-08 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
TW200507893A (en) * 2003-03-31 2005-03-01 Alza Corp Osmotic pump with means for dissipating internal pressure
US8361490B2 (en) * 2004-09-16 2013-01-29 Theracoat Ltd. Biocompatible drug delivery apparatus and methods
JP5265359B2 (ja) 2005-08-11 2013-08-14 マサチューセッツ インスティテュート オブ テクノロジー 膀胱内薬物送達デバイスおよび方法
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JP5913095B2 (ja) 2009-06-26 2016-04-27 タリス バイオメディカル エルエルシー 植込み型薬物送達装置及びその作製方法
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MX367070B (es) * 2012-08-31 2019-08-05 Taris Biomedical Llc Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata.
CA2902556C (en) 2013-03-15 2021-06-22 Heejin Lee Drug delivery devices and methods for drug delivery
JP6517186B2 (ja) * 2013-03-15 2019-05-22 タリス バイオメディカル エルエルシー 薬物透過性構成部材を備えた薬物送達デバイス、及び方法
CA2919215C (en) * 2013-08-19 2022-11-29 Taris Biomedical Llc Multi-unit drug delivery devices and methods
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MX2016011333A (es) * 2014-03-06 2016-12-07 Taris Biomedical Llc Sistemas de administracion de farmaco y metodo para el tratamiento de cancer de vejiga con gemcitabina.

Also Published As

Publication number Publication date
US20220347091A1 (en) 2022-11-03
JP2017508749A (ja) 2017-03-30
KR20160124425A (ko) 2016-10-27
SMT202500385T1 (it) 2025-11-10
SG11201607342QA (en) 2016-10-28
ES2930435T3 (es) 2022-12-13
BR112016020381A2 (pt) 2017-08-15
AU2015226901B2 (en) 2020-05-14
MX2016011333A (es) 2016-12-07
RS63675B1 (sr) 2022-11-30
JP7061595B2 (ja) 2022-04-28
JP2024009034A (ja) 2024-01-19
AU2024259822A1 (en) 2024-11-28
US20150250717A1 (en) 2015-09-10
EP3113782A1 (en) 2017-01-11
WO2015134911A1 (en) 2015-09-11
CN106102751A (zh) 2016-11-09
AU2020217383A1 (en) 2020-09-03
IL247347B2 (en) 2025-03-01
BR112016020381A8 (pt) 2018-05-02
AU2020217383B2 (en) 2022-09-08
JP6901858B2 (ja) 2021-07-14
EP4124339A1 (en) 2023-02-01
HUE060704T2 (hu) 2023-04-28
US20220117886A1 (en) 2022-04-21
JP2022022235A (ja) 2022-02-03
CN119950539A (zh) 2025-05-09
IL311410A (en) 2024-05-01
HRP20251264T1 (hr) 2025-12-05
NZ723303A (en) 2023-10-27
IL311410B2 (en) 2025-11-01
IL247347B1 (en) 2024-11-01
AU2015226901A1 (en) 2016-09-01
LT3113782T (lt) 2022-11-25
JP7383681B2 (ja) 2023-11-20
PT3113782T (pt) 2023-01-05
PL4124339T3 (pl) 2025-11-17
SI4124339T1 (sl) 2025-11-28
SG10202101978SA (en) 2021-04-29
EP4124339B1 (en) 2025-09-10
SMT202200449T1 (it) 2023-01-13
LT4124339T (lt) 2025-11-10
RU2694902C1 (ru) 2019-07-18
AU2022215156B2 (en) 2024-09-05
RS67337B1 (sr) 2025-11-28
JP2019218410A (ja) 2019-12-26
EP3113782B1 (en) 2022-09-28
AU2022215156A1 (en) 2022-09-01
DK3113782T3 (da) 2022-10-17
PL3113782T3 (pl) 2023-01-23
CA2939979C (en) 2023-03-21
CA2939979A1 (en) 2015-09-11
IL247347A0 (en) 2016-11-30
FI4124339T3 (fi) 2025-10-17
KR102338079B1 (ko) 2021-12-09
HRP20221252T1 (hr) 2022-12-09
PT4124339T (pt) 2025-11-04
IL311410B1 (en) 2025-07-01

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