DK411687A - 1-(4-alkansulfonamidophenyl)-4-(4-alkansulfonamidophenylalkyl)piperazin-forbindelser og deres anvendelse som antiarytmiske midler samt forbindelser til anvendelse som udgangsmateriale ved deres fremstilling - Google Patents

1-(4-alkansulfonamidophenyl)-4-(4-alkansulfonamidophenylalkyl)piperazin-forbindelser og deres anvendelse som antiarytmiske midler samt forbindelser til anvendelse som udgangsmateriale ved deres fremstilling

Info

Publication number
DK411687A
DK411687A DK411687A DK411687A DK411687A DK 411687 A DK411687 A DK 411687A DK 411687 A DK411687 A DK 411687A DK 411687 A DK411687 A DK 411687A DK 411687 A DK411687 A DK 411687A
Authority
DK
Denmark
Prior art keywords
agents
arthymic
alkansulphonamidophenylalkyl
alkansulphonamidophenyl
material materials
Prior art date
Application number
DK411687A
Other languages
English (en)
Other versions
DK169129B1 (da
DK411687D0 (da
Inventor
Peter Edward Cross
John Edward Glyn Kemp
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of DK411687D0 publication Critical patent/DK411687D0/da
Publication of DK411687A publication Critical patent/DK411687A/da
Application granted granted Critical
Publication of DK169129B1 publication Critical patent/DK169129B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
DK411687A 1986-08-09 1987-08-07 1-(4-Alkansulfonamidophenyl)-4-(4-alkansulfonamidophenylalkyl)piperazin-derivater, disse forbindelser til anvendelse som lægemidler, farmaceutiske præparater indeholdende forbindelserne og anvendelse af forbindelserne til fremstilling af antiarytmiske lægemidler samt mellemprodukter ved fremstilling af forbindelserne DK169129B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868619472A GB8619472D0 (en) 1986-08-09 1986-08-09 Anti-arrhythmia agents
GB8619472 1986-08-09

Publications (3)

Publication Number Publication Date
DK411687D0 DK411687D0 (da) 1987-08-07
DK411687A true DK411687A (da) 1988-04-28
DK169129B1 DK169129B1 (da) 1994-08-22

Family

ID=10602501

Family Applications (1)

Application Number Title Priority Date Filing Date
DK411687A DK169129B1 (da) 1986-08-09 1987-08-07 1-(4-Alkansulfonamidophenyl)-4-(4-alkansulfonamidophenylalkyl)piperazin-derivater, disse forbindelser til anvendelse som lægemidler, farmaceutiske præparater indeholdende forbindelserne og anvendelse af forbindelserne til fremstilling af antiarytmiske lægemidler samt mellemprodukter ved fremstilling af forbindelserne

Country Status (11)

Country Link
US (1) US4797401A (da)
EP (1) EP0257864B1 (da)
JP (1) JPS6344572A (da)
AT (1) ATE58898T1 (da)
DE (1) DE3766570D1 (da)
DK (1) DK169129B1 (da)
ES (1) ES2031509T3 (da)
GB (1) GB8619472D0 (da)
GR (1) GR3001231T3 (da)
IE (1) IE60030B1 (da)
PT (1) PT85506B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
US5051423A (en) * 1988-07-13 1991-09-24 Schering Ag Derivatized alkanolamines as cardiovascular agents
DE3933163A1 (de) * 1988-10-27 1990-05-03 Toyoda Gosei Kk Zylindrische daempfungsbuchse
US5033872A (en) * 1989-09-06 1991-07-23 Toyoda Gosei Co., Ltd. Bushing
US5051422A (en) * 1989-09-15 1991-09-24 Schering Ag 2-substituted-1(4)-aryl piperazines and the process for their preparation
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
US6083991A (en) 1997-06-04 2000-07-04 University Of Florida Research Foundation, Inc. Anti-arrhythmic composition and methods of treatment
ATE384048T1 (de) * 1998-09-22 2008-02-15 Astellas Pharma Inc Cyanophenyl-derivate
CN110156729B (zh) * 2019-05-14 2022-12-06 浙江大学 一种苯基哌嗪类ube2f小分子抑制剂及其合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB997166A (en) * 1961-07-14 1965-07-07 May & Baker Ltd N-phenylpiperazine derivatives
ES291187A1 (es) * 1963-04-04 1964-01-16 American Cyanamid Co Un procedimiento para preparar piperazinas sustituidas
US3331845A (en) * 1963-04-04 1967-07-18 American Cyanamid Co 1-substituted-4-substituted amino alkylene piperazines
BE654017A (da) * 1963-04-04 1965-04-06
US3822266A (en) * 1968-12-24 1974-07-02 Hoffmann La Roche (3-(1-piperazinyl)-2-hydroxy-propoxy)acetanilides
CA967965A (en) * 1968-12-24 1975-05-20 Hoffmann-La Roche Limited Aromatic ethers and process for the manufacture thereof
US3758692A (en) * 1969-04-14 1973-09-11 Mead Johnson & Co Ylamines sympathomimetic process and compositions employing sulfonamidophenalk
BE757005A (fr) * 1969-10-02 1971-04-02 Bristol Myers Co Phenethanolamines substituees et procede pour leur preparation
US3764602A (en) * 1969-12-04 1973-10-09 Hoffmann La Roche 3-(4-phenyl-1 2, 6 di keto piperazinyl)-2-hydroxy-propoxy)-aniline
US3930004A (en) * 1970-11-10 1975-12-30 Pfizer Method of using phenoxypropanolpiperazine compounds to lower blood pressure
GB1361863A (en) * 1972-09-25 1974-07-30 Pfizer Ltd Piperazine derivatives their preparation and pharmaceutical compositions containing them
FR2515648A1 (fr) * 1981-11-03 1983-05-06 Cortial Nouvelles (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof

Also Published As

Publication number Publication date
ES2031509T3 (es) 1992-12-16
IE872120L (en) 1988-02-09
US4797401A (en) 1989-01-10
EP0257864B1 (en) 1990-12-05
JPS6344572A (ja) 1988-02-25
DK169129B1 (da) 1994-08-22
EP0257864A1 (en) 1988-03-02
JPH0567150B2 (da) 1993-09-24
GB8619472D0 (en) 1986-09-17
IE60030B1 (en) 1994-05-18
ATE58898T1 (de) 1990-12-15
GR3001231T3 (en) 1992-07-30
PT85506B (pt) 1990-06-29
DE3766570D1 (de) 1991-01-17
DK411687D0 (da) 1987-08-07
PT85506A (en) 1987-09-01

Similar Documents

Publication Publication Date Title
DK91889D0 (da) 5-lipoxygenaseinhiberende 4-(4-phenyl-1-piperazinyl)phenoler
DK411687A (da) 1-(4-alkansulfonamidophenyl)-4-(4-alkansulfonamidophenylalkyl)piperazin-forbindelser og deres anvendelse som antiarytmiske midler samt forbindelser til anvendelse som udgangsmateriale ved deres fremstilling
AU1328088A (en) Herbicidal compounds
DK0600629T3 (da) N-acetonylbenzamider og deres anvendelse som fungicider
DK0511541T3 (da)
DE69023321D1 (de) Antipicornaviral-Pyridazinamine.
ATE102929T1 (de) Antirhinovirale piperidinyl-, pyrrolidinyl- und piperazinyl-alkylphenolether.
DK0494604T3 (da) 1-Piperazinyl-2-butener og -2-butyner, mellemprodukter derfor, en fremgangsmåde til fremstilling deraf og deres anvendelse
ES2044883T3 (es) Procedimiento para preparar quinoxalinas sustituidas.
DK0587048T3 (da) Heteroarenylpiperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
GB2182934B (en) Piperidine derivatives

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK