DK405884A - Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler - Google Patents

Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler Download PDF

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Publication number
DK405884A
DK405884A DK405884A DK405884A DK405884A DK 405884 A DK405884 A DK 405884A DK 405884 A DK405884 A DK 405884A DK 405884 A DK405884 A DK 405884A DK 405884 A DK405884 A DK 405884A
Authority
DK
Denmark
Prior art keywords
spiro
azalkanes
benzofuran
medicines
procedures
Prior art date
Application number
DK405884A
Other languages
English (en)
Other versions
DK405884D0 (da
Inventor
Jr Raymond W Kosley
Robert J Cherill
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK405884D0 publication Critical patent/DK405884D0/da
Publication of DK405884A publication Critical patent/DK405884A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK405884A 1983-08-25 1984-08-24 Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler DK405884A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/526,193 US4452802A (en) 1983-08-25 1983-08-25 Antihypertensive spiro[benzofuran-azalkanes]

Publications (2)

Publication Number Publication Date
DK405884D0 DK405884D0 (da) 1984-08-24
DK405884A true DK405884A (da) 1985-02-26

Family

ID=24096310

Family Applications (1)

Application Number Title Priority Date Filing Date
DK405884A DK405884A (da) 1983-08-25 1984-08-24 Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler

Country Status (8)

Country Link
US (1) US4452802A (da)
EP (1) EP0139138B1 (da)
JP (1) JPS6072892A (da)
AT (1) ATE28200T1 (da)
DE (1) DE3464609D1 (da)
DK (1) DK405884A (da)
ES (1) ES8607313A1 (da)
GR (1) GR80173B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788201A (en) * 1987-01-22 1988-11-29 Hoechst-Roussel Pharmaceuticals Inc. 3-methylenespiro (benzofuranpiperidines)
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
NZ243065A (en) 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
DE69412067T2 (de) * 1993-01-28 1999-03-25 Merck & Co Inc Substituierte spiro-azaringen als tachykinine rezeptor antagonisten
US8193208B2 (en) * 2005-09-09 2012-06-05 Purdue Pharma L.P. Fused and spirocycle compounds and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962259A (en) * 1973-12-12 1976-06-08 American Hoechst Corporation 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof
US4166119A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4166120A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines

Also Published As

Publication number Publication date
DK405884D0 (da) 1984-08-24
JPS6072892A (ja) 1985-04-24
EP0139138B1 (en) 1987-07-08
ES535357A0 (es) 1986-05-16
DE3464609D1 (en) 1987-08-13
US4452802A (en) 1984-06-05
GR80173B (en) 1985-01-02
ES8607313A1 (es) 1986-05-16
EP0139138A1 (en) 1985-05-02
ATE28200T1 (de) 1987-07-15

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Legal Events

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ATS Application withdrawn