DK405884A - Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler - Google Patents
Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler Download PDFInfo
- Publication number
- DK405884A DK405884A DK405884A DK405884A DK405884A DK 405884 A DK405884 A DK 405884A DK 405884 A DK405884 A DK 405884A DK 405884 A DK405884 A DK 405884A DK 405884 A DK405884 A DK 405884A
- Authority
- DK
- Denmark
- Prior art keywords
- spiro
- azalkanes
- benzofuran
- medicines
- procedures
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000003003 spiro group Chemical group 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/526,193 US4452802A (en) | 1983-08-25 | 1983-08-25 | Antihypertensive spiro[benzofuran-azalkanes] |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK405884D0 DK405884D0 (da) | 1984-08-24 |
| DK405884A true DK405884A (da) | 1985-02-26 |
Family
ID=24096310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK405884A DK405884A (da) | 1983-08-25 | 1984-08-24 | Spiro(benzofuran-azalkaner), fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4452802A (da) |
| EP (1) | EP0139138B1 (da) |
| JP (1) | JPS6072892A (da) |
| AT (1) | ATE28200T1 (da) |
| DE (1) | DE3464609D1 (da) |
| DK (1) | DK405884A (da) |
| ES (1) | ES8607313A1 (da) |
| GR (1) | GR80173B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788201A (en) * | 1987-01-22 | 1988-11-29 | Hoechst-Roussel Pharmaceuticals Inc. | 3-methylenespiro (benzofuranpiperidines) |
| IL96507A0 (en) * | 1989-12-08 | 1991-08-16 | Merck & Co Inc | Nitrogen-containing spirocycles and pharmaceutical compositions containing them |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
| DE69412067T2 (de) * | 1993-01-28 | 1999-03-25 | Merck & Co., Inc., Rahway, N.J. | Substituierte spiro-azaringen als tachykinine rezeptor antagonisten |
| JP2009507800A (ja) | 2005-09-09 | 2009-02-26 | ユーロ−セルティーク エス．エイ． | 縮合およびスピロ環化合物ならびにその使用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962259A (en) * | 1973-12-12 | 1976-06-08 | American Hoechst Corporation | 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof |
| US4166120A (en) * | 1978-04-14 | 1979-08-28 | American Hoechst Corporation | Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines |
| US4166119A (en) * | 1978-04-14 | 1979-08-28 | American Hoechst Corporation | Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines |
-
1983
- 1983-08-25 US US06/526,193 patent/US4452802A/en not_active Expired - Fee Related
-
1984
- 1984-08-14 EP EP84109647A patent/EP0139138B1/en not_active Expired
- 1984-08-14 AT AT84109647T patent/ATE28200T1/de not_active IP Right Cessation
- 1984-08-14 DE DE8484109647T patent/DE3464609D1/de not_active Expired
- 1984-08-23 GR GR80173A patent/GR80173B/el unknown
- 1984-08-23 ES ES535357A patent/ES8607313A1/es not_active Expired
- 1984-08-24 DK DK405884A patent/DK405884A/da not_active Application Discontinuation
- 1984-08-24 JP JP59175334A patent/JPS6072892A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0139138B1 (en) | 1987-07-08 |
| DK405884D0 (da) | 1984-08-24 |
| ES535357A0 (es) | 1986-05-16 |
| ATE28200T1 (de) | 1987-07-15 |
| GR80173B (en) | 1985-01-02 |
| EP0139138A1 (en) | 1985-05-02 |
| DE3464609D1 (en) | 1987-08-13 |
| ES8607313A1 (es) | 1986-05-16 |
| JPS6072892A (ja) | 1985-04-24 |
| US4452802A (en) | 1984-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |