CA1223831A
(en)
|
1982-06-23 |
1987-07-07 |
Dean Engelhardt |
Modified nucleotides, methods of preparing and utilizing and compositions containing the same
|
US7220854B1
(en)
|
1982-06-23 |
2007-05-22 |
Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. |
Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides
|
US5175269A
(en)
*
|
1984-01-30 |
1992-12-29 |
Enzo Diagnostics, Inc. |
Compound and detectable molecules having an oligo- or polynucleotide with modifiable reactive group
|
AU580042B2
(en)
*
|
1984-03-22 |
1988-12-22 |
Bresatec Limited |
Non-radioactive biological probes
|
US4828979A
(en)
*
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
JPH0723393B2
(ja)
*
|
1985-05-15 |
1995-03-15 |
アモコ・コーポレーション |
シチジン同族体
|
US5011913A
(en)
*
|
1985-06-28 |
1991-04-30 |
The Procter & Gamble Company |
Diphosphonate-derivatized macromolecules
|
US5155216A
(en)
*
|
1985-08-15 |
1992-10-13 |
Amoco Corporation |
Nucleic acids labeled with a chemiluminescent acridine ester
|
US6280929B1
(en)
|
1986-01-16 |
2001-08-28 |
The Regents Of The University Of California |
Method of detecting genetic translocations identified with chromosomal abnormalities
|
US5721098A
(en)
*
|
1986-01-16 |
1998-02-24 |
The Regents Of The University Of California |
Comparative genomic hybridization
|
US6475720B1
(en)
|
1986-01-16 |
2002-11-05 |
The Regents Of The University Of California |
Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
|
US5447841A
(en)
|
1986-01-16 |
1995-09-05 |
The Regents Of The Univ. Of California |
Methods for chromosome-specific staining
|
US6872817B1
(en)
|
1986-01-16 |
2005-03-29 |
The Regents Of The Univ. Of California |
Method of staining target interphase chromosomal DNA
|
US7115709B1
(en)
|
1986-01-16 |
2006-10-03 |
The Regents Of The University Of California |
Methods of staining target chromosomal DNA employing high complexity nucleic acid probes
|
US5756696A
(en)
*
|
1986-01-16 |
1998-05-26 |
Regents Of The University Of California |
Compositions for chromosome-specific staining
|
US4797491A
(en)
*
|
1986-03-17 |
1989-01-10 |
Cetus Corporation |
Compound 1-(3-(2-pyridyldithio)propionamido)-12-(5-hydrazidoglutaramido)-4,9-dioxadodecane
|
GB8610551D0
(en)
*
|
1986-04-30 |
1986-06-04 |
Hoffmann La Roche |
Polypeptide & protein derivatives
|
US6451225B1
(en)
|
1986-04-30 |
2002-09-17 |
Igen International, Inc. |
Electrochemiluminescent reaction utilizing amine-derived reductant
|
US5591581A
(en)
*
|
1986-04-30 |
1997-01-07 |
Igen, Inc. |
Electrochemiluminescent rhenium moieties and methods for their use
|
US6165729A
(en)
*
|
1986-04-30 |
2000-12-26 |
Hyperion Catalysis International, Inc. |
Electrochemiluminescent reaction utilizing amine-derived reductant
|
US4925804A
(en)
*
|
1986-06-17 |
1990-05-15 |
Baxter International Inc. |
Interligand metal transfer assay
|
SE454781B
(sv)
*
|
1986-10-17 |
1988-05-30 |
Wallac Oy |
Hybridiseringsforfarande for detektion av polynukleotidsekvens
|
EP0266099A3
(de)
*
|
1986-10-28 |
1990-09-19 |
The Johns Hopkins University |
Alkyl- oder Arylphosphonat-Oligonukleosid, das sich mit Nukleinesäuren vernetzen kann oder das Nukleinsäure spalten kann
|
AU2714988A
(en)
*
|
1987-10-23 |
1989-06-01 |
Siska Diagnostics, Inc. |
Lanthanide chelate-tagged nucleic acid probes
|
US4971902A
(en)
*
|
1987-10-30 |
1990-11-20 |
Virginia Mason Research Center |
Diagnostic probe for rheumatoid arthritis predisposition
|
USH545H
(en)
|
1987-10-30 |
1988-11-01 |
The United States Of America As Represented By The United States Department Of Energy |
In vivo generator for radioimmunotherapy
|
WO1989004302A1
(en)
*
|
1987-11-04 |
1989-05-18 |
Igen, Inc. |
Electrochemiluminescent rhenium moieties and methods
|
US6326136B1
(en)
|
1988-04-01 |
2001-12-04 |
Digene Corporation |
Macromolecular conjugate made using unsaturated aldehydes
|
US6702986B1
(en)
|
1988-04-29 |
2004-03-09 |
Igen International, Inc. |
Electrochemiluminescent reaction utilizing amine-derived reductant
|
US5047523A
(en)
*
|
1988-08-02 |
1991-09-10 |
Ortho Diagnostic Systems Inc. |
Nucleic acid probe for detection of neisseria gonorrhoea
|
US6203977B1
(en)
*
|
1988-11-15 |
2001-03-20 |
Yale University |
Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization
|
US5324829A
(en)
*
|
1988-12-16 |
1994-06-28 |
Ortho Diagnostic Systems, Inc. |
High specific activity nucleic acid probes having target recognition and signal generating moieties
|
CA2005927A1
(en)
*
|
1988-12-21 |
1990-06-21 |
Chander Bahl |
Method of preparing nucleotide probes using a bridging complement
|
US5998135A
(en)
*
|
1989-02-24 |
1999-12-07 |
Enzo Diagnostics, Inc. |
Energy transfer hybridization assay using intercalators and lanthanide metals
|
US5334729A
(en)
*
|
1989-06-29 |
1994-08-02 |
Associated Universities, Inc. |
Stable radiometal antibody immunoconjugates
|
US5089663A
(en)
*
|
1989-06-29 |
1992-02-18 |
Associated Universities, Inc. |
Cyclohexyl-triethylenetetraamine hexacetic acid
|
US8592155B2
(en)
*
|
1989-07-19 |
2013-11-26 |
The Regents Of The University Of California |
Method of detecting genetic deletions identified with chromosomal abnormalities
|
WO1991013080A1
(en)
*
|
1990-02-20 |
1991-09-05 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
US5453517A
(en)
*
|
1992-02-25 |
1995-09-26 |
Molecular Probes, Inc. |
Reactive derivatives of bapta used to make ion-selective chelators
|
US5552541A
(en)
*
|
1990-06-20 |
1996-09-03 |
Beckman Instruments, Inc. |
Haptenic probes for detecting capture polynucleotides
|
US5386023A
(en)
*
|
1990-07-27 |
1995-01-31 |
Isis Pharmaceuticals |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
|
US5541307A
(en)
*
|
1990-07-27 |
1996-07-30 |
Isis Pharmaceuticals, Inc. |
Backbone modified oligonucleotide analogs and solid phase synthesis thereof
|
JP2646814B2
(ja)
*
|
1990-08-07 |
1997-08-27 |
アイシン精機株式会社 |
核酸等の検定方法
|
US5264343A
(en)
*
|
1990-08-31 |
1993-11-23 |
Eleanor Roosevelt Institute |
Method for distinguishing normal and cancer cells
|
JPH04222600A
(ja)
*
|
1990-12-21 |
1992-08-12 |
Aisin Seiki Co Ltd |
ナフトール誘導体ホスフェートによる核酸等の検定方法
|
US5128476A
(en)
*
|
1991-02-20 |
1992-07-07 |
The Midland Certified Reagent Company |
Biotinylated oligonucleotides and reagents for preparing the same
|
US5965722A
(en)
*
|
1991-05-21 |
1999-10-12 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
|
US5965362A
(en)
*
|
1992-03-04 |
1999-10-12 |
The Regents Of The University Of California |
Comparative genomic hybridization (CGH)
|
EP0631635B1
(de)
*
|
1992-03-04 |
2001-09-12 |
The Regents Of The University Of California |
Vergleichende genomhybridisierung
|
US7534567B2
(en)
*
|
1992-03-04 |
2009-05-19 |
The Regents Of The University Of California |
Detection of nucleic acid sequence differences by comparative genomic hybridization
|
US5292938A
(en)
*
|
1992-04-13 |
1994-03-08 |
Associated Universities, Inc. |
Synthesis of 4-substituted-trans-1, 2-diaminocyclohexyl polyaminocarboxylate metal chelating agents for the preparation of stable radiometal antibody immunoconjugates for therapy and spect and pet imaging
|
GB2284208A
(en)
*
|
1993-11-25 |
1995-05-31 |
Pna Diagnostics As |
Nucleic acid analogues with a chelating functionality for metal ions
|
US5446137B1
(en)
*
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
US5952172A
(en)
|
1993-12-10 |
1999-09-14 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
US6071699A
(en)
|
1996-06-07 |
2000-06-06 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
US5591578A
(en)
|
1993-12-10 |
1997-01-07 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
US5824473A
(en)
|
1993-12-10 |
1998-10-20 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
EP0738158B1
(de)
*
|
1994-01-12 |
2002-04-03 |
Amersham plc |
Biologische zielgerichtete mittel
|
US20110097791A1
(en)
*
|
1999-04-16 |
2011-04-28 |
Engelhardt Dean L |
Novel process, construct and conjugate for producing multiple nucleic acid copies
|
US20050123926A1
(en)
*
|
1994-01-13 |
2005-06-09 |
Enzo Diagnostics, Inc., |
In vitro process for producing multiple nucleic acid copies
|
US6986985B1
(en)
|
1994-01-13 |
2006-01-17 |
Enzo Life Sciences, Inc. |
Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct
|
CA2140081C
(en)
|
1994-01-13 |
2008-04-01 |
Dean L. Engelhardt |
Process, construct and conjugate for producing multiple nucleic acid copies
|
JPH09508358A
(ja)
*
|
1994-01-14 |
1997-08-26 |
マリンクロット・メディカル・インコーポレテイッド |
血管再狭窄を抑止するための医療的処置
|
FR2724461B1
(fr)
*
|
1994-09-09 |
1996-12-20 |
Prolabo Sa |
Microsphere de latex biotinylee, procede de preparation d'une telle microsphere et utilisation en tant qu'agent de detection biologique
|
US5620850A
(en)
|
1994-09-26 |
1997-04-15 |
President And Fellows Of Harvard College |
Molecular recognition at surfaces derivatized with self-assembled monolayers
|
US5830645A
(en)
|
1994-12-09 |
1998-11-03 |
The Regents Of The University Of California |
Comparative fluorescence hybridization to nucleic acid arrays
|
US6589502B1
(en)
*
|
1995-11-27 |
2003-07-08 |
International Brachytherapy S.A. |
Radioisotope dispersed in a matrix for brachytherapy
|
CA2279673A1
(en)
|
1995-12-15 |
1997-06-16 |
Enzo Therapeutics, Inc. |
Property effecting and/or property exhibiting constructs for the expression of non-native nucleic acids for therapeutic and diagnostic uses
|
US6444423B1
(en)
|
1996-06-07 |
2002-09-03 |
Molecular Dynamics, Inc. |
Nucleosides comprising polydentate ligands
|
US7045285B1
(en)
*
|
1996-11-05 |
2006-05-16 |
Clinical Micro Sensors, Inc. |
Electronic transfer moieties attached to peptide nucleic acids
|
US7393645B2
(en)
*
|
1996-11-05 |
2008-07-01 |
Clinical Micro Sensors, Inc. |
Compositions for the electronic detection of analytes utilizing monolayers
|
US7381525B1
(en)
|
1997-03-07 |
2008-06-03 |
Clinical Micro Sensors, Inc. |
AC/DC voltage apparatus for detection of nucleic acids
|
US6096273A
(en)
|
1996-11-05 |
2000-08-01 |
Clinical Micro Sensors |
Electrodes linked via conductive oligomers to nucleic acids
|
US7160678B1
(en)
|
1996-11-05 |
2007-01-09 |
Clinical Micro Sensors, Inc. |
Compositions for the electronic detection of analytes utilizing monolayers
|
US7014992B1
(en)
*
|
1996-11-05 |
2006-03-21 |
Clinical Micro Sensors, Inc. |
Conductive oligomers attached to electrodes and nucleoside analogs
|
EP0878552A1
(de)
|
1997-05-13 |
1998-11-18 |
Erasmus Universiteit Rotterdam |
Molekularer Nachweis von chromosomalen Veränderungen
|
US6013459A
(en)
*
|
1997-06-12 |
2000-01-11 |
Clinical Micro Sensors, Inc. |
Detection of analytes using reorganization energy
|
US7070921B2
(en)
|
2000-04-28 |
2006-07-04 |
Molecular Devices Corporation |
Molecular modification assays
|
US7745142B2
(en)
|
1997-09-15 |
2010-06-29 |
Molecular Devices Corporation |
Molecular modification assays
|
US7632651B2
(en)
|
1997-09-15 |
2009-12-15 |
Mds Analytical Technologies (Us) Inc. |
Molecular modification assays
|
US6297018B1
(en)
|
1998-04-17 |
2001-10-02 |
Ljl Biosystems, Inc. |
Methods and apparatus for detecting nucleic acid polymorphisms
|
US6982431B2
(en)
|
1998-08-31 |
2006-01-03 |
Molecular Devices Corporation |
Sample analysis systems
|
US6686150B1
(en)
|
1998-01-27 |
2004-02-03 |
Clinical Micro Sensors, Inc. |
Amplification of nucleic acids with electronic detection
|
US7090804B2
(en)
|
1998-01-27 |
2006-08-15 |
Clinical Mirco Sensors, Inc. |
Amplification of nucleic acids with electronic detection
|
WO1999057309A1
(en)
|
1998-05-04 |
1999-11-11 |
Dako A/S |
Method and probes for the detection of chromosome aberrations
|
US6153442A
(en)
*
|
1998-05-20 |
2000-11-28 |
Dade Behring Inc. |
Reagents and methods for specific binding assays
|
US7087148B1
(en)
|
1998-06-23 |
2006-08-08 |
Clinical Micro Sensors, Inc. |
Binding acceleration techniques for the detection of analytes
|
US6290839B1
(en)
|
1998-06-23 |
2001-09-18 |
Clinical Micro Sensors, Inc. |
Systems for electrophoretic transport and detection of analytes
|
US6761816B1
(en)
|
1998-06-23 |
2004-07-13 |
Clinical Micro Systems, Inc. |
Printed circuit boards with monolayers and capture ligands
|
US8445664B2
(en)
*
|
1998-06-24 |
2013-05-21 |
Enzo Diagnostics, Inc. |
Kits for amplifying and detecting nucleic acid sequences
|
US6743605B1
(en)
|
1998-06-24 |
2004-06-01 |
Enzo Life Sciences, Inc. |
Linear amplification of specific nucleic acid sequences
|
US6740518B1
(en)
|
1998-09-17 |
2004-05-25 |
Clinical Micro Sensors, Inc. |
Signal detection techniques for the detection of analytes
|
US6541617B1
(en)
*
|
1998-10-27 |
2003-04-01 |
Clinical Micro Sensors, Inc. |
Detection of target analytes using particles and electrodes
|
US6833267B1
(en)
*
|
1998-12-30 |
2004-12-21 |
Clinical Micro Sensors, Inc. |
Tissue collection devices containing biosensors
|
US7312087B2
(en)
*
|
2000-01-11 |
2007-12-25 |
Clinical Micro Sensors, Inc. |
Devices and methods for biochip multiplexing
|
US20020177135A1
(en)
|
1999-07-27 |
2002-11-28 |
Doung Hau H. |
Devices and methods for biochip multiplexing
|
US6942771B1
(en)
|
1999-04-21 |
2005-09-13 |
Clinical Micro Sensors, Inc. |
Microfluidic systems in the electrochemical detection of target analytes
|
JP4056701B2
(ja)
*
|
1999-05-14 |
2008-03-05 |
ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア |
薬剤および診断薬の送達のための高分子担体
|
AU779220B2
(en)
|
1999-07-26 |
2005-01-13 |
Clinical Micro Sensors, Inc. |
Sequence determination of nucleic acids using electronic detection
|
US7102024B1
(en)
|
2000-08-01 |
2006-09-05 |
Schwartz David A |
Functional biopolymer modification reagents and uses thereof
|
CA2723664A1
(en)
*
|
2000-03-22 |
2001-09-27 |
Solulink, Incorporated |
Hydrazine-based and carbonyl-based bifunctional crosslinking reagents
|
US6686461B1
(en)
|
2000-03-22 |
2004-02-03 |
Solulink Bioscience, Inc. |
Triphosphate oligonucleotide modification reagents and uses thereof
|
TWI290136B
(en)
|
2000-04-05 |
2007-11-21 |
Daiichi Seiyaku Co |
Ethylenediamine derivatives
|
US6753143B2
(en)
|
2000-05-01 |
2004-06-22 |
Clinical Micro Sensors, Inc. |
Target analyte detection using asymmetrical self-assembled monolayers
|
JP4382265B2
(ja)
*
|
2000-07-12 |
2009-12-09 |
日本電気株式会社 |
酸化シリコン膜の形成方法及びその形成装置
|
US20040265870A1
(en)
*
|
2003-04-09 |
2004-12-30 |
Invitrogen Corporation |
Methods of synthesizing and labeling nucleic acid molecules
|
US7158353B2
(en)
*
|
2003-11-06 |
2007-01-02 |
Seagate Technology Llc |
Magnetoresistive sensor having specular sidewall layers
|
US20050123932A1
(en)
*
|
2003-12-09 |
2005-06-09 |
Mekbib Astatke |
Nucleic acid-chelating agent conjugates
|
WO2005079474A2
(en)
*
|
2004-02-17 |
2005-09-01 |
The Regents Of The University Of California |
Detection of nucleic acid sequence differences by comparative genomic hybridization
|
US7737281B2
(en)
*
|
2005-05-24 |
2010-06-15 |
Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. |
Purine based fluorescent dyes
|
US7569695B2
(en)
*
|
2005-05-24 |
2009-08-04 |
Enzo Life Sciences, Inc. |
Dyes for the detection or quantification of desirable target molecules
|
US8357801B2
(en)
|
2005-05-24 |
2013-01-22 |
Enzo Life Sciences, Inc. |
Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits
|
US20090162845A1
(en)
*
|
2007-12-20 |
2009-06-25 |
Elazar Rabbani |
Affinity tag nucleic acid and protein compositions, and processes for using same
|
DK2757091T3
(en)
|
2008-04-01 |
2017-08-14 |
Biosearch Tech Inc |
PROBLEMS FOR STABILIZED NUCLEIC ACID DARK-QUENCHER FLUOROPHOR
|
US8314151B2
(en)
*
|
2008-04-29 |
2012-11-20 |
Enzo Therapeutics, Inc. |
Sphingosine kinase type 1 inhibitors, and processes for using same
|
US8372888B2
(en)
*
|
2008-04-29 |
2013-02-12 |
Enzo Therapeutics, Inc. |
Sphingosine kinase type 1 inhibitors, compositions and processes for using same
|
JP2018512167A
(ja)
|
2015-04-15 |
2018-05-17 |
バイオサーチ テクノロジーズ インコーポレイテッド |
ダブルクエンチャープローブ
|
US10660879B2
(en)
|
2017-06-23 |
2020-05-26 |
Enzo Biochem, Inc. |
Sphingosine pathway modulating compounds for the treatment of cancers
|
CA3061201A1
(en)
|
2017-06-23 |
2018-12-27 |
Enzo Biochem, Inc. |
Sphingosine pathway modulating compounds for the treatment of cancers
|
CN108467354A
(zh)
*
|
2018-04-09 |
2018-08-31 |
西尼尔(江西)化工科技有限公司 |
3,3’-二硫代二丙酸双(异辛醇酯)的制备方法及其应用
|
CN110368899A
(zh)
*
|
2019-07-16 |
2019-10-25 |
邱越 |
一种活性炭复合材料及其制备方法和应用
|
WO2023018805A1
(en)
|
2021-08-11 |
2023-02-16 |
Sanofi Pasteur Inc. |
Methods and related aspects of detecting and purifying influenza neuraminidase
|