DK39490A - Dibenzo-cycloheptenyl-, -cycloheptyl- og -oxepinyl-aminer med antihistamin-egenskaber - Google Patents
Dibenzo-cycloheptenyl-, -cycloheptyl- og -oxepinyl-aminer med antihistamin-egenskaber Download PDFInfo
- Publication number
- DK39490A DK39490A DK039490A DK39490A DK39490A DK 39490 A DK39490 A DK 39490A DK 039490 A DK039490 A DK 039490A DK 39490 A DK39490 A DK 39490A DK 39490 A DK39490 A DK 39490A
- Authority
- DK
- Denmark
- Prior art keywords
- oxepinyl
- cycloheptenyl
- dibenzo
- cycloheptyl
- amines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/207,840 US4912222A (en) | 1988-06-17 | 1988-06-17 | Antihistamines related to cyproheptadine |
| US07/207,839 US4855462A (en) | 1988-06-17 | 1988-06-17 | Antihistamines |
| PCT/US1989/002556 WO1989012443A1 (en) | 1988-06-17 | 1989-06-15 | Novel dibenzo-cycloheptenyl, -cycloheptyl and -oxepinyl amines having antihistaminic properties |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK39490D0 DK39490D0 (da) | 1990-02-15 |
| DK39490A true DK39490A (da) | 1990-04-11 |
Family
ID=26902658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK039490A DK39490A (da) | 1988-06-17 | 1990-02-15 | Dibenzo-cycloheptenyl-, -cycloheptyl- og -oxepinyl-aminer med antihistamin-egenskaber |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0347123A3 (da) |
| JP (1) | JPH03500053A (da) |
| AU (1) | AU3850389A (da) |
| DK (1) | DK39490A (da) |
| PT (1) | PT90868A (da) |
| WO (1) | WO1989012443A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250681A (en) * | 1988-06-02 | 1993-10-05 | Ajinomoto Co., Inc. | Piperidine derivatives and hypotensives containing the same |
| CA2004211A1 (en) * | 1988-11-30 | 1990-05-31 | Masataka Syoji | Piperidine derivatives and hyportensives containing the same |
| AU620996B2 (en) * | 1989-07-04 | 1992-02-27 | Hokuriku Pharmaceutical Co. Ltd. | 4-{(dibenzocycloheptene) or (dibenzoxepin)}-1-substituted piperidines |
| AU3170793A (en) * | 1991-12-25 | 1993-07-28 | Zeria Pharmaceutical Co., Ltd. | Tricyclic compound and medicine containing the same |
| US5801175A (en) * | 1995-04-07 | 1998-09-01 | Schering Corporation | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| US5874442A (en) | 1995-12-22 | 1999-02-23 | Schering-Plough Corporation | Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease |
| FR2795724B1 (fr) * | 1999-07-02 | 2002-12-13 | Sanofi Synthelabo | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
| US6743941B2 (en) | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
| CN101522665B (zh) * | 2006-09-29 | 2012-02-08 | 日本脏器制药株式会社 | *庚英衍生物 |
| KR102236857B1 (ko) | 2018-12-28 | 2021-04-06 | 강원대학교산학협력단 | 시프로헵타딘 유도체, 이의 제조방법 및 이를 포함하는 식욕 촉진용 조성물 |
| CN113880801A (zh) * | 2020-07-03 | 2022-01-04 | 合肥医工医药股份有限公司 | 一类三环化合物、其制备方法及其医药用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3014911A (en) * | 1958-09-29 | 1961-12-26 | Merck & Co Inc | Derivatives of dibenzo[a, e]cycloheptatriene |
| DE1269614B (de) * | 1961-02-08 | 1968-06-06 | Hoffmann La Roche | Verfahren zur Herstellung von antidepressiv wirksamen sekundaeren Aminderivaten des 5H-Dibenzo [a, d]-cycloheptens bzw. 10, 11-Dihydro-5H-dibenzo[a, d]-cycloheptens |
| US3309404A (en) * | 1962-04-04 | 1967-03-14 | Merck & Co Inc | Derivatives of dibenzocycloheptenes and a process for their preparation |
| US3420851A (en) * | 1962-12-19 | 1969-01-07 | Pfizer & Co C | Novel dibenzoxepines |
| FR1488972A (fr) * | 1965-05-25 | 1967-07-21 | Rhone Poulenc Sa | Nouveaux dérivés du dibenzocycloheptatriene et leur préparation |
| FR1478356A (fr) * | 1965-08-31 | 1967-04-28 | Rhone Poulenc Sa | Nouveaux dérivés du dibenzocycloheptadiène et leur préparation |
| US3428735A (en) * | 1967-08-24 | 1969-02-18 | Merck & Co Inc | Method of treating depression with 5-(3-dimethylaminopropylidene)dibenzo(a,d) (1,4)cycloheptadiene or its non-toxic salts thereof |
| DE1802631A1 (de) * | 1968-10-11 | 1970-06-11 | Leo Ab | Neue chemotherapeutisch wirksame tricyclische Aminoketone und Verfahren zu deren Herstellung |
| US3878217A (en) * | 1972-01-28 | 1975-04-15 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
| JPS5018478A (da) * | 1973-05-17 | 1975-02-26 | ||
| DE2335943C3 (de) * | 1973-07-14 | 1979-08-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Tricyclisch substituierte Aminoalkohole und ihre nichttoxischen Salze, Verfahren zu deren Herstellung und deren Verwendung bei der Bekämpfung von Herz- und Kreislauferkrankungen |
| US4086350A (en) * | 1974-11-06 | 1978-04-25 | Smithkline Corporation | Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms |
| US4356184A (en) * | 1980-06-04 | 1982-10-26 | G. D. Searle & Co. | Anti-allergic or antihypertensive 1-piperidinylmethyl benzenamines |
| EP0294183B1 (en) * | 1987-06-02 | 1994-03-30 | Ajinomoto Co., Inc. | Use of ethylamine derivatives as antihypertensive agents |
| CA2004211A1 (en) * | 1988-11-30 | 1990-05-31 | Masataka Syoji | Piperidine derivatives and hyportensives containing the same |
-
1989
- 1989-06-09 EP EP19890305858 patent/EP0347123A3/en not_active Withdrawn
- 1989-06-15 JP JP1507343A patent/JPH03500053A/ja active Pending
- 1989-06-15 WO PCT/US1989/002556 patent/WO1989012443A1/en unknown
- 1989-06-15 PT PT90868A patent/PT90868A/pt not_active Application Discontinuation
- 1989-06-15 AU AU38503/89A patent/AU3850389A/en not_active Abandoned
-
1990
- 1990-02-15 DK DK039490A patent/DK39490A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0347123A3 (en) | 1991-07-03 |
| EP0347123A2 (en) | 1989-12-20 |
| PT90868A (pt) | 1989-12-29 |
| DK39490D0 (da) | 1990-02-15 |
| JPH03500053A (ja) | 1991-01-10 |
| AU3850389A (en) | 1990-01-12 |
| WO1989012443A1 (en) | 1989-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |