DK3942020T3 - Metoder til opnåelse af inducerede gladte muskelceller - Google Patents
Metoder til opnåelse af inducerede gladte muskelceller Download PDFInfo
- Publication number
- DK3942020T3 DK3942020T3 DK20711954.6T DK20711954T DK3942020T3 DK 3942020 T3 DK3942020 T3 DK 3942020T3 DK 20711954 T DK20711954 T DK 20711954T DK 3942020 T3 DK3942020 T3 DK 3942020T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- smooth muscle
- muscle cells
- induced smooth
- obtaining induced
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0661—Smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
- C12N2501/91—Heparin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1323—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from skeletal muscle cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Developmental Biology & Embryology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19164574 | 2019-03-22 | ||
| PCT/EP2020/057940 WO2020193460A1 (en) | 2019-03-22 | 2020-03-23 | Methods for obtaining induced smooth muscle cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3942020T3 true DK3942020T3 (da) | 2024-07-15 |
Family
ID=65904308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20711954.6T DK3942020T3 (da) | 2019-03-22 | 2020-03-23 | Metoder til opnåelse af inducerede gladte muskelceller |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US12312600B2 (enExample) |
| EP (2) | EP4397752A3 (enExample) |
| JP (2) | JP7616665B2 (enExample) |
| KR (1) | KR20220002315A (enExample) |
| CN (2) | CN113614223B (enExample) |
| AU (1) | AU2020247211B2 (enExample) |
| BR (1) | BR112021016264A2 (enExample) |
| CL (1) | CL2021002169A1 (enExample) |
| DK (1) | DK3942020T3 (enExample) |
| ES (1) | ES2987152T3 (enExample) |
| IL (1) | IL286509B2 (enExample) |
| MX (1) | MX2021009862A (enExample) |
| WO (1) | WO2020193460A1 (enExample) |
| ZA (1) | ZA202104948B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102780297B1 (ko) | 2017-12-14 | 2025-03-12 | 이노바셀 바이오테크놀로지 아게 | 근육 유래 세포를 수득하는 방법 |
| KR20220002315A (ko) | 2019-03-22 | 2022-01-06 | 이노바셀 아게 | 유도된 평활근 세포를 수득하는 방법 |
| EP4741009A3 (en) | 2021-08-06 | 2026-08-12 | Innovacell GmbH | Myogenic progenitor cells for use in an optimized method for the prevention and treatment of anal incontinence |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US8211423B2 (en) * | 2006-11-28 | 2012-07-03 | University Of Pittsburgh | Muscle derived cells for the treatment of cardiac pathologies and methods of making and using the same |
| US6555374B1 (en) * | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
| AU5159901A (en) | 2000-04-14 | 2001-10-30 | Univ Pittsburgh | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof |
| JPWO2003027281A1 (ja) | 2001-09-20 | 2005-01-06 | 協和醗酵工業株式会社 | 骨格筋間質由来多分化能幹細胞 |
| ATE482713T1 (de) | 2003-04-25 | 2010-10-15 | Univ Pittsburgh | Von muskeln stammende zellen (mdcs) zur förderung und verbesserung der nervenreparatur und - regeneration |
| WO2007010858A1 (ja) * | 2005-07-15 | 2007-01-25 | Kyoto University | 骨格筋組織由来の単一細胞よりクローン化した多能性幹細胞 |
| FR2890977A1 (fr) | 2005-09-19 | 2007-03-23 | Assist Publ Hopitaux De Paris | Procede d'obtention de cellules musculaires lisses humaines et leurs applications |
| US20100273231A1 (en) * | 2005-09-20 | 2010-10-28 | Andreadis Stelios T | Multipotent mesenchymal stem cells from human hair follicles |
| WO2007106200A2 (en) | 2006-01-10 | 2007-09-20 | Theradigm, Inc. | Expansion and differentiation of neural stem cells under low oxygen conditions |
| US20080208164A1 (en) | 2007-02-28 | 2008-08-28 | Innovacell Biotechnologie Gmbh | Methods for the treatment of anal incontinence |
| US20090155221A1 (en) | 2007-05-29 | 2009-06-18 | Thomas Payne | Bone augmentation utilizing muscle-derived progenitor compositions, and treatments thereof |
| EP2206774A1 (en) | 2008-12-23 | 2010-07-14 | Genzyme Corporation | Muscle-derived cells having differentiation capacities |
| US20140030236A1 (en) * | 2010-02-25 | 2014-01-30 | The Johns Hopkins University | Derivation and maturation of synthetic and contractile vascular smooth muscle cells from human pluripotent stem cells |
| CN106267352A (zh) * | 2010-05-03 | 2017-01-04 | 再生医学（开曼）有限公司 | 平滑肌细胞结构 |
| WO2014039654A1 (en) * | 2012-09-06 | 2014-03-13 | Joslin Diabetes Center, Inc. | Isolation and characterization of muscle regenerating cells |
| WO2014044867A1 (en) * | 2012-09-24 | 2014-03-27 | Innovacell Biotechnologie Ag | Potency assay for skeletal muscle derived cells |
| EP3056562A1 (en) * | 2015-02-11 | 2016-08-17 | University College Cork-National University of Ireland, Cork | Induced smooth muscle-type cells, methods for the production thereof, and uses thereof in cell-based tissue regeneration and treatment of vascular occlusion |
| CN106350480B (zh) | 2016-08-26 | 2019-11-08 | 中国农业科学院北京畜牧兽医研究所 | 一种纯化牛胎儿骨骼肌组织来源成肌细胞的方法 |
| KR102780297B1 (ko) | 2017-12-14 | 2025-03-12 | 이노바셀 바이오테크놀로지 아게 | 근육 유래 세포를 수득하는 방법 |
| KR20220002315A (ko) | 2019-03-22 | 2022-01-06 | 이노바셀 아게 | 유도된 평활근 세포를 수득하는 방법 |
| EP4741009A3 (en) | 2021-08-06 | 2026-08-12 | Innovacell GmbH | Myogenic progenitor cells for use in an optimized method for the prevention and treatment of anal incontinence |
-
2020
- 2020-03-23 KR KR1020217034375A patent/KR20220002315A/ko active Pending
- 2020-03-23 BR BR112021016264-0A patent/BR112021016264A2/pt unknown
- 2020-03-23 EP EP24175168.4A patent/EP4397752A3/en not_active Withdrawn
- 2020-03-23 WO PCT/EP2020/057940 patent/WO2020193460A1/en not_active Ceased
- 2020-03-23 ES ES20711954T patent/ES2987152T3/es active Active
- 2020-03-23 US US17/441,690 patent/US12312600B2/en active Active
- 2020-03-23 DK DK20711954.6T patent/DK3942020T3/da active
- 2020-03-23 CN CN202080021489.4A patent/CN113614223B/zh active Active
- 2020-03-23 MX MX2021009862A patent/MX2021009862A/es unknown
- 2020-03-23 EP EP20711954.6A patent/EP3942020B1/en active Active
- 2020-03-23 CN CN202510688777.XA patent/CN120738111A/zh active Pending
- 2020-03-23 AU AU2020247211A patent/AU2020247211B2/en active Active
- 2020-03-23 JP JP2021552231A patent/JP7616665B2/ja active Active
-
2021
- 2021-07-14 ZA ZA2021/04948A patent/ZA202104948B/en unknown
- 2021-08-16 CL CL2021002169A patent/CL2021002169A1/es unknown
- 2021-09-19 IL IL286509A patent/IL286509B2/en unknown
-
2024
- 2024-10-11 JP JP2024179303A patent/JP2025011242A/ja active Pending
-
2025
- 2025-03-10 US US19/075,289 patent/US20250207097A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020193460A1 (en) | 2020-10-01 |
| JP2025011242A (ja) | 2025-01-23 |
| CN113614223B (zh) | 2025-05-27 |
| IL286509A (en) | 2021-10-31 |
| JP7616665B2 (ja) | 2025-01-17 |
| CL2021002169A1 (es) | 2022-02-25 |
| IL286509B1 (en) | 2026-04-01 |
| US20220145257A1 (en) | 2022-05-12 |
| CN113614223A (zh) | 2021-11-05 |
| JP2022526229A (ja) | 2022-05-24 |
| EP4397752A3 (en) | 2024-10-02 |
| AU2020247211B2 (en) | 2024-07-04 |
| US20250207097A1 (en) | 2025-06-26 |
| EP3942020B1 (en) | 2024-05-15 |
| MX2021009862A (es) | 2021-09-14 |
| NZ778000A (en) | 2025-07-25 |
| CN120738111A (zh) | 2025-10-03 |
| KR20220002315A (ko) | 2022-01-06 |
| CA3134213A1 (en) | 2020-10-01 |
| ZA202104948B (en) | 2024-08-28 |
| BR112021016264A2 (pt) | 2021-10-13 |
| US12312600B2 (en) | 2025-05-27 |
| AU2020247211A1 (en) | 2021-07-29 |
| IL286509B2 (en) | 2026-08-01 |
| EP3942020A1 (en) | 2022-01-26 |
| ES2987152T3 (es) | 2024-11-14 |
| EP4397752A2 (en) | 2024-07-10 |
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