DK385085A - CRYSTALLIC SODIUM SALT OF D-6- (ALFA - ((2-OXO-3-FURFURYLIDEN-AMINOIMIDAZOLIDIN-1-YL) CARBONYLAMINO) -THIENYL-2-ACETAMIDO) -PENICILLANIC ACID, EXCEPT PREPARED TO EXCEED - Google Patents
CRYSTALLIC SODIUM SALT OF D-6- (ALFA - ((2-OXO-3-FURFURYLIDEN-AMINOIMIDAZOLIDIN-1-YL) CARBONYLAMINO) -THIENYL-2-ACETAMIDO) -PENICILLANIC ACID, EXCEPT PREPARED TO EXCEED Download PDFInfo
- Publication number
- DK385085A DK385085A DK385085A DK385085A DK385085A DK 385085 A DK385085 A DK 385085A DK 385085 A DK385085 A DK 385085A DK 385085 A DK385085 A DK 385085A DK 385085 A DK385085 A DK 385085A
- Authority
- DK
- Denmark
- Prior art keywords
- carbonylamino
- oxo
- sodium salt
- furfuryliden
- aminoimidazolidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/70—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with hetero rings as additional substituents on the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Abstract
1. Sodium salt of D-6-{alpha-[(2-oxo-3- furfurylideneamino-imidazolidin-1-yl)-carbonylamino]-2- thienylacetamido}-penicillanic acid of the formula (I) see diagramm : EP0176716,P8,F2 in pure crystalline form, characterized by the following NMR signals : delta = 9.36 (1H), 9.23 (1H), 7.8 (2H), 7.5 (1H), 7.25 (1H), 7.05 (1H), 6.89 (1H), 6.62 (1H), 6.2 (1H), 5.74 (1H), 5.56 (1H), 4.35 (1H), 3.92 (4H), 1.6 (3H) and 1,5 ppm (3H) (in DMF-d7 ).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843431273 DE3431273A1 (en) | 1984-08-25 | 1984-08-25 | CRYSTALLINE SODIUM SALT OF THE D-6 - ((ALPHA) - (2-OXO-3-FURFURYL-IDEN-AMINO-IMIDAZOLIDIN-1-YL) -CARBONYLAMINO) -THIENYL-2-ACETAMIDO) -PENICILLANIC ACID, METHODS OF PROCESSING IN MEDICINAL PRODUCTS |
CN85106479A CN85106479B (en) | 1984-08-25 | 1985-08-29 | Crystalline D-6 {alpha-[(2-aldo-3-furfurylidene-amino-1-imidazolidinyl) carbonyl amino]-2 thienylacetamido}-penicillanic acid salt with sodium, process thereof and use as medicine |
Publications (2)
Publication Number | Publication Date |
---|---|
DK385085D0 DK385085D0 (en) | 1985-08-23 |
DK385085A true DK385085A (en) | 1986-02-26 |
Family
ID=25741999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK385085A DK385085A (en) | 1984-08-25 | 1985-08-23 | CRYSTALLIC SODIUM SALT OF D-6- (ALFA - ((2-OXO-3-FURFURYLIDEN-AMINOIMIDAZOLIDIN-1-YL) CARBONYLAMINO) -THIENYL-2-ACETAMIDO) -PENICILLANIC ACID, EXCEPT PREPARED TO EXCEED |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0176716B1 (en) |
JP (1) | JPS6157589A (en) |
KR (1) | KR860001818A (en) |
CN (1) | CN85106479B (en) |
AT (1) | ATE34576T1 (en) |
AU (1) | AU559040B2 (en) |
DE (2) | DE3431273A1 (en) |
DK (1) | DK385085A (en) |
ES (1) | ES8609340A1 (en) |
FI (1) | FI853211L (en) |
GR (1) | GR852047B (en) |
HU (1) | HU194893B (en) |
IL (1) | IL76164A0 (en) |
NO (1) | NO853188L (en) |
NZ (1) | NZ213198A (en) |
PH (1) | PH21842A (en) |
PT (1) | PT81014B (en) |
ZA (1) | ZA856413B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW347383B (en) * | 1995-10-26 | 1998-12-11 | Biochemie Gmbh | A process for the production of a crystalline sodium salt of amoxicillin in ethanol as solvent |
US9844374B2 (en) | 2014-12-18 | 2017-12-19 | Ethicon Llc | Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL85039B1 (en) * | 1972-02-17 | 1977-02-26 | Tarchomińskie Zakłady Farmaceutyczne | Method for the preparation of sodium salt of α-ftminobenzylopeiiicylmy |
PL87153B1 (en) * | 1973-07-13 | 1976-12-15 | Tarchomińskie Zakłady Farmaceutyczne | Method of obtaining crystalline penicillin disodium salt of α-carboxybenzyl |
DE2732323A1 (en) * | 1977-07-16 | 1979-01-25 | Bayer Ag | BETA-LACTAM COMPOUNDS, THE PROCESS FOR THEIR PRODUCTION AND THEIR USE |
DE2732283A1 (en) * | 1977-07-16 | 1979-01-25 | Bayer Ag | BETA-LACTAM COMPOUNDS |
JPS5940727A (en) * | 1982-07-28 | 1984-03-06 | Fujitsu Ltd | Automatic equalization system |
-
1984
- 1984-08-25 DE DE19843431273 patent/DE3431273A1/en not_active Withdrawn
-
1985
- 1985-08-13 NO NO853188A patent/NO853188L/en unknown
- 1985-08-14 DE DE8585110189T patent/DE3562918D1/en not_active Expired
- 1985-08-14 AT AT85110189T patent/ATE34576T1/en active
- 1985-08-14 EP EP85110189A patent/EP0176716B1/en not_active Expired
- 1985-08-21 FI FI853211A patent/FI853211L/en not_active Application Discontinuation
- 1985-08-22 NZ NZ213198A patent/NZ213198A/en unknown
- 1985-08-22 IL IL76164A patent/IL76164A0/en unknown
- 1985-08-22 AU AU46577/85A patent/AU559040B2/en not_active Ceased
- 1985-08-23 PH PH32687A patent/PH21842A/en unknown
- 1985-08-23 HU HU853216A patent/HU194893B/en not_active IP Right Cessation
- 1985-08-23 JP JP60185652A patent/JPS6157589A/en active Pending
- 1985-08-23 PT PT81014A patent/PT81014B/en not_active IP Right Cessation
- 1985-08-23 ZA ZA856413A patent/ZA856413B/en unknown
- 1985-08-23 GR GR852047A patent/GR852047B/el unknown
- 1985-08-23 DK DK385085A patent/DK385085A/en not_active Application Discontinuation
- 1985-08-23 ES ES546379A patent/ES8609340A1/en not_active Expired
- 1985-08-24 KR KR1019850006132A patent/KR860001818A/en not_active IP Right Cessation
- 1985-08-29 CN CN85106479A patent/CN85106479B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FI853211L (en) | 1986-02-26 |
FI853211A0 (en) | 1985-08-21 |
EP0176716A1 (en) | 1986-04-09 |
ES546379A0 (en) | 1986-07-16 |
PH21842A (en) | 1988-03-17 |
CN85106479B (en) | 1988-07-27 |
DK385085D0 (en) | 1985-08-23 |
AU559040B2 (en) | 1987-02-19 |
EP0176716B1 (en) | 1988-05-25 |
ATE34576T1 (en) | 1988-06-15 |
IL76164A0 (en) | 1985-12-31 |
JPS6157589A (en) | 1986-03-24 |
HUT38354A (en) | 1986-05-28 |
PT81014A (en) | 1985-09-01 |
NZ213198A (en) | 1989-02-24 |
PT81014B (en) | 1987-12-30 |
ES8609340A1 (en) | 1986-07-16 |
NO853188L (en) | 1986-02-26 |
AU4657785A (en) | 1986-02-27 |
KR860001818A (en) | 1986-03-22 |
HU194893B (en) | 1988-03-28 |
GR852047B (en) | 1985-12-20 |
DE3431273A1 (en) | 1986-03-06 |
CN85106479A (en) | 1987-03-18 |
ZA856413B (en) | 1986-04-30 |
DE3562918D1 (en) | 1988-06-30 |
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Legal Events
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ATS | Application withdrawn |