DK375188A - Fremgangsmaade til fremstilling af et biologisk aktivt kompleks og det fremstillede kompleks - Google Patents
Fremgangsmaade til fremstilling af et biologisk aktivt kompleks og det fremstillede kompleksInfo
- Publication number
- DK375188A DK375188A DK375188A DK375188A DK375188A DK 375188 A DK375188 A DK 375188A DK 375188 A DK375188 A DK 375188A DK 375188 A DK375188 A DK 375188A DK 375188 A DK375188 A DK 375188A
- Authority
- DK
- Denmark
- Prior art keywords
- complex
- molecule
- inactivation
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/82—Asparaginase (3.5.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6815—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6871—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an enzyme
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7186187A | 1987-07-07 | 1987-07-07 | |
US18253088A | 1988-04-18 | 1988-04-18 | |
US20574888A | 1988-06-21 | 1988-06-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK375188D0 DK375188D0 (da) | 1988-07-06 |
DK375188A true DK375188A (da) | 1989-01-08 |
Family
ID=27371979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK375188A DK375188A (da) | 1987-07-07 | 1988-07-06 | Fremgangsmaade til fremstilling af et biologisk aktivt kompleks og det fremstillede kompleks |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0298654B1 (da) |
JP (1) | JPH01138461A (da) |
AT (1) | ATE106250T1 (da) |
AU (1) | AU1865288A (da) |
DE (1) | DE3889783T2 (da) |
DK (1) | DK375188A (da) |
ES (1) | ES2056108T3 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5686579A (en) * | 1988-06-21 | 1997-11-11 | Hybrisens, Ltd. | Use of antibody/antigen interactions to protect biologically active proteins and peptides |
JPH03133378A (ja) * | 1989-07-19 | 1991-06-06 | Modrovich Ivan E | 被験体を安定化させて液体中でのその生物学的活性を保存する方法 |
ATE193600T1 (de) * | 1990-11-20 | 2000-06-15 | Dade Behring Marburg Gmbh | Verfahren zur stabilisierung von enzym-konjugaten |
AU6953696A (en) * | 1996-08-16 | 1998-03-06 | Procter & Gamble Company, The | Detergent compositions comprising antibody controlled amylolytic activity |
WO1998007820A1 (en) * | 1996-08-16 | 1998-02-26 | The Procter & Gamble Company | Detergent compositions comprising antibody controlled enzymatic activity |
AU6849696A (en) * | 1996-08-16 | 1998-03-06 | Procter & Gamble Company, The | Detergent compositions comprising antibody controlled proteolytic activity |
AU6953796A (en) * | 1996-08-16 | 1998-03-06 | Procter & Gamble Company, The | Detergent compositions comprising antibody controlled cellulolytic activity |
AU6777296A (en) * | 1996-08-16 | 1998-03-06 | Procter & Gamble Company, The | Detergent compositions comprising antibody controlled lipolytic activity |
WO1998007816A1 (en) * | 1996-08-16 | 1998-02-26 | The Procter & Gamble Company | Detergent compositions comprising oxido-reductase antibody |
US9321832B2 (en) | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
WO2005094881A1 (ja) * | 2004-03-30 | 2005-10-13 | Takeda Pharmaceutical Company Limited | 抗体医薬 |
RU2401842C2 (ru) * | 2004-10-08 | 2010-10-20 | Домантис Лимитед | Антагонисты и способы их применения |
CA2637707A1 (en) | 2006-02-02 | 2007-08-09 | Rinat Neuroscience Corporation | Methods for treating obesity by administering a trkb antagonist |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2148299B (en) * | 1983-09-01 | 1988-01-06 | Hybritech Inc | Antibody compositions of therapeutic agents having an extended serum half-life |
EP0231649B1 (en) * | 1985-12-28 | 1990-11-22 | Nippon Hypox Laboratories Incorporated | Albumin complex |
DE3621828A1 (de) * | 1986-06-28 | 1988-01-14 | Biotest Pharma Gmbh | Stabilisierung eines fuer therapeutische zwecke, insbesondere beim menschen, bestimmten interleukin-2-praeparates sowie dieses praeparat enthaltende stabilisierte waessrige loesung oder feststoff |
US4704692A (en) * | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
-
1988
- 1988-06-30 EP EP88305934A patent/EP0298654B1/en not_active Expired - Lifetime
- 1988-06-30 ES ES88305934T patent/ES2056108T3/es not_active Expired - Lifetime
- 1988-06-30 DE DE3889783T patent/DE3889783T2/de not_active Expired - Fee Related
- 1988-06-30 AT AT88305934T patent/ATE106250T1/de not_active IP Right Cessation
- 1988-07-04 AU AU18652/88A patent/AU1865288A/en not_active Abandoned
- 1988-07-06 DK DK375188A patent/DK375188A/da not_active Application Discontinuation
- 1988-07-07 JP JP63167854A patent/JPH01138461A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0298654A2 (en) | 1989-01-11 |
AU1865288A (en) | 1989-01-12 |
ATE106250T1 (de) | 1994-06-15 |
DK375188D0 (da) | 1988-07-06 |
DE3889783D1 (de) | 1994-07-07 |
ES2056108T3 (es) | 1994-10-01 |
EP0298654B1 (en) | 1994-06-01 |
EP0298654A3 (en) | 1990-02-07 |
DE3889783T2 (de) | 1994-09-08 |
JPH01138461A (ja) | 1989-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |