DK367787A - 6-thioxanthiner og salte deraf samt deres fremstilling og anvendelse - Google Patents

6-thioxanthiner og salte deraf samt deres fremstilling og anvendelse

Info

Publication number
DK367787A
DK367787A DK367787A DK367787A DK367787A DK 367787 A DK367787 A DK 367787A DK 367787 A DK367787 A DK 367787A DK 367787 A DK367787 A DK 367787A DK 367787 A DK367787 A DK 367787A
Authority
DK
Denmark
Prior art keywords
group
thioxanthines
alkyl
salts
preparation
Prior art date
Application number
DK367787A
Other languages
English (en)
Other versions
DK367787D0 (da
DK161965C (da
DK161965B (da
Inventor
Peter Hofer
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of DK367787D0 publication Critical patent/DK367787D0/da
Publication of DK367787A publication Critical patent/DK367787A/da
Publication of DK161965B publication Critical patent/DK161965B/da
Application granted granted Critical
Publication of DK161965C publication Critical patent/DK161965C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DK367787A 1986-08-02 1987-07-15 6-thioxanthiner og salte deraf samt deres fremstilling og anvendelse DK161965C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8618931 1986-08-02
GB868618931A GB8618931D0 (en) 1986-08-02 1986-08-02 6-thioxanthines

Publications (4)

Publication Number Publication Date
DK367787D0 DK367787D0 (da) 1987-07-15
DK367787A true DK367787A (da) 1988-02-03
DK161965B DK161965B (da) 1991-09-02
DK161965C DK161965C (da) 1992-02-10

Family

ID=10602146

Family Applications (1)

Application Number Title Priority Date Filing Date
DK367787A DK161965C (da) 1986-08-02 1987-07-15 6-thioxanthiner og salte deraf samt deres fremstilling og anvendelse

Country Status (13)

Country Link
US (2) US4925847A (da)
EP (1) EP0256692B1 (da)
JP (1) JP2590120B2 (da)
AT (1) ATE80632T1 (da)
AU (1) AU601456B2 (da)
CA (1) CA1276147C (da)
DE (1) DE3781743T2 (da)
DK (1) DK161965C (da)
ES (1) ES2046204T3 (da)
GB (1) GB8618931D0 (da)
GR (1) GR3005997T3 (da)
IE (1) IE60510B1 (da)
ZA (1) ZA875346B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
AU5436790A (en) * 1989-04-19 1990-11-16 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Sulfer-containing xanthine derivatives as adenosin antagonists
JPH06102662B2 (ja) * 1989-09-01 1994-12-14 協和醗酵工業株式会社 キサンチン誘導体
US5290782A (en) * 1989-09-01 1994-03-01 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
EP0799040B1 (en) * 1994-12-13 2003-08-20 Euroceltique S.A. Trisubstituted thioxanthines
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
ATE247116T1 (de) 1994-12-13 2003-08-15 Euro Celtique Sa Arylthioxanthine
US6268373B1 (en) 1995-06-07 2001-07-31 Euro-Celtique S.A. Trisubstituted thioxanthines
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
AU1723099A (en) 1997-12-12 1999-07-05 Euro-Celtique S.A. 3-substituted adenines via2-thioxanthines
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
HUP0200938A2 (en) 1999-04-02 2002-10-28 Euro Celtique Sa Purine derivatives having phosphodiesterase iv inhibition activity and medicaments containing them
US7005430B2 (en) 1999-12-24 2006-02-28 Kyowa Hakko Kogyo Co., Ltd. Fused purine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR188M (fr) * 1960-01-28 1961-02-20 May & Baker Ltd Nouveaux dérivés de la thioxanthine et les compositions pharmaceutiques qui les contiennent.
US3900474A (en) * 1973-05-14 1975-08-19 Kendall & Co Trifluoroalkyl, fluorobenzyl, pentafluorobenzyl, fluorobenzenesulfonyl, and pentafluorobenzenesulfonyl theophyllines
SE8002910L (sv) * 1980-04-18 1981-10-19 Draco Ab 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines

Also Published As

Publication number Publication date
DK367787D0 (da) 1987-07-15
GR3005997T3 (da) 1993-06-07
JP2590120B2 (ja) 1997-03-12
AU601456B2 (en) 1990-09-13
DE3781743T2 (de) 1993-03-25
EP0256692B1 (en) 1992-09-16
EP0256692A2 (en) 1988-02-24
US4925847A (en) 1990-05-15
CA1276147C (en) 1990-11-13
ATE80632T1 (de) 1992-10-15
DK161965C (da) 1992-02-10
IE60510B1 (en) 1994-07-27
AU7628687A (en) 1988-02-04
GB8618931D0 (en) 1986-09-10
ES2046204T3 (es) 1994-02-01
US5010081A (en) 1991-04-23
DK161965B (da) 1991-09-02
JPS6341478A (ja) 1988-02-22
EP0256692A3 (en) 1989-08-30
IE872074L (en) 1988-02-02
ZA875346B (en) 1988-01-27
DE3781743D1 (en) 1992-10-22

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