DK3649257T3 - Berigelse af målrettede genomiske regioner til multiplekset parallel analyse - Google Patents

Berigelse af målrettede genomiske regioner til multiplekset parallel analyse Download PDF

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Publication number
DK3649257T3
DK3649257T3 DK18745508.4T DK18745508T DK3649257T3 DK 3649257 T3 DK3649257 T3 DK 3649257T3 DK 18745508 T DK18745508 T DK 18745508T DK 3649257 T3 DK3649257 T3 DK 3649257T3
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enrichment
genomic regions
parallel analysis
targeted genomic
multiplex parallel
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DK18745508.4T
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George Koumbaris
Marios Ioannides
Elena KYPRI
Acilleas Achilleos
Petros MINA
Kyriakos Tsangaras
Philippos Patsalis
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Nipd Genetics Public Company Ltd
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    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10Complex mathematical operations
    • G06F17/18Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10Modifications characterised by
    • C12Q2525/185Modifications characterised by incorporating bases where the precise position of the bases in the nucleic acid string is important
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    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2535/00Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
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    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/159Reduction of complexity, e.g. amplification of subsets, removing duplicated genomic regions
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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DK18745508.4T 2017-07-07 2018-07-06 Berigelse af målrettede genomiske regioner til multiplekset parallel analyse DK3649257T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762529667P 2017-07-07 2017-07-07
PCT/EP2018/068402 WO2019008148A1 (en) 2017-07-07 2018-07-06 ENRICHMENT OF TARGETED GENOMIC REGIONS FOR MULTIPLEXED PARALLEL ANALYSIS

Publications (1)

Publication Number Publication Date
DK3649257T3 true DK3649257T3 (da) 2022-07-04

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DK18745508.4T DK3649257T3 (da) 2017-07-07 2018-07-06 Berigelse af målrettede genomiske regioner til multiplekset parallel analyse

Country Status (11)

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US (1) US20200157602A1 (da)
EP (1) EP3649257B1 (da)
AU (1) AU2018296568A1 (da)
CA (1) CA3068198A1 (da)
CY (1) CY1125226T1 (da)
DK (1) DK3649257T3 (da)
ES (1) ES2920280T3 (da)
PL (1) PL3649257T3 (da)
PT (1) PT3649257T (da)
WO (1) WO2019008148A1 (da)
ZA (1) ZA201908614B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3649259T3 (da) 2017-07-07 2022-08-15 Nipd Genetics Public Company Ltd Target-beriget multiplekset parallel analyse til vurdering af risiko for genetiske tilstande
AU2018298437A1 (en) 2017-07-07 2020-01-16 Medicover Public Co Ltd Target-enriched multiplexed parallel analysis for assessment of fetal DNA samples
CN113621692B (zh) * 2021-10-12 2022-02-22 北京求臻医疗器械有限公司 人类fgfr1基因拷贝数变异核酸标准物质及其制备方法、及试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2429408T5 (es) 2006-02-02 2020-01-16 Univ Leland Stanford Junior Examen genético fetal no invasivo mediante análisis digital
US20080194414A1 (en) * 2006-04-24 2008-08-14 Albert Thomas J Enrichment and sequence analysis of genomic regions
WO2008027548A2 (en) * 2006-09-01 2008-03-06 Dana-Farber Cancer Institute, Inc. Microarray-based global chromatin structure mapping
EP3378951B1 (en) 2008-09-20 2020-05-13 The Board of Trustees of the Leland Stanford Junior University Noninvasive diagnosis of aneuploidy by sequencing
US20110039304A1 (en) * 2009-08-12 2011-02-17 President And Fellows Of Harvard College Methods to Generate Oligonucleotide Pools and Enrich Target Nucleic Acid Sequences
US20110160076A1 (en) * 2009-12-31 2011-06-30 Ventana Medical Systems, Inc. Methods for producing uniquely specific nucleic acid probes
US20120270739A1 (en) 2010-01-19 2012-10-25 Verinata Health, Inc. Method for sample analysis of aneuploidies in maternal samples
EP2366031B1 (en) 2010-01-19 2015-01-21 Verinata Health, Inc Sequencing methods in prenatal diagnoses
US20130123120A1 (en) * 2010-05-18 2013-05-16 Natera, Inc. Highly Multiplex PCR Methods and Compositions
EP3760731A1 (en) * 2011-02-09 2021-01-06 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20150203907A1 (en) * 2014-01-17 2015-07-23 Florida State University Research Foundation Genome capture and sequencing to determine genome-wide copy number variation
GB201414451D0 (en) * 2014-08-14 2014-10-01 Oxford Gene Technology Operations Ltd Hybridisation column for nucleic acid enrichment
WO2016040446A1 (en) * 2014-09-10 2016-03-17 Good Start Genetics, Inc. Methods for selectively suppressing non-target sequences
ES2790533T3 (es) 2015-05-22 2020-10-28 Nipd Genetics Public Company Ltd Análisis paralelo múltiplex de regiones genómicas blanco para análisis prenatales no invasivos

Also Published As

Publication number Publication date
PT3649257T (pt) 2022-05-19
US20200157602A1 (en) 2020-05-21
ES2920280T3 (es) 2022-08-02
PL3649257T3 (pl) 2022-07-18
EP3649257B1 (en) 2022-03-30
WO2019008148A9 (en) 2019-05-16
WO2019008148A1 (en) 2019-01-10
EP3649257A1 (en) 2020-05-13
ZA201908614B (en) 2022-07-27
CA3068198A1 (en) 2019-01-10
AU2018296568A1 (en) 2020-01-16
CY1125226T1 (el) 2024-09-20

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