DK364181A - Fremgangsmaade til fremstilling af caprolactamderivater - Google Patents

Fremgangsmaade til fremstilling af caprolactamderivater

Info

Publication number
DK364181A
DK364181A DK364181A DK364181A DK364181A DK 364181 A DK364181 A DK 364181A DK 364181 A DK364181 A DK 364181A DK 364181 A DK364181 A DK 364181A DK 364181 A DK364181 A DK 364181A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
caprolactam derivatives
caprolactam
derivatives
Prior art date
Application number
DK364181A
Other languages
Danish (da)
English (en)
Inventor
E E Harris
A A Patchett
E D Thorsett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK364181A publication Critical patent/DK364181A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
DK364181A 1980-08-18 1981-08-17 Fremgangsmaade til fremstilling af caprolactamderivater DK364181A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17930580A 1980-08-18 1980-08-18
US28258081A 1981-07-13 1981-07-13

Publications (1)

Publication Number Publication Date
DK364181A true DK364181A (da) 1982-02-19

Family

ID=26875204

Family Applications (1)

Application Number Title Priority Date Filing Date
DK364181A DK364181A (da) 1980-08-18 1981-08-17 Fremgangsmaade til fremstilling af caprolactamderivater

Country Status (6)

Country Link
EP (1) EP0046291B1 (fr)
DE (1) DE3173304D1 (fr)
DK (1) DK364181A (fr)
ES (2) ES8305337A1 (fr)
GR (1) GR74635B (fr)
PT (1) PT73537B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3260831D1 (en) * 1981-06-05 1984-10-31 Merck & Co Inc Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4410807A (en) * 1982-03-26 1983-10-18 Kay Industries, Inc. Regulating device for polyphase electrical circuits
US4473575A (en) * 1982-07-19 1984-09-25 Ciba-Geigy Corporation 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
EP0107095B1 (fr) * 1982-09-30 1987-09-09 Merck & Co. Inc. 1-N-carboxyalkyl-benzolactames utiles comme agents antihypertensifs
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
US4537885A (en) * 1983-02-10 1985-08-27 Ciba Geigy Corporation Certain benzazocinone and benzazoninone derivatives
US4711884A (en) * 1983-02-28 1987-12-08 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
US4460579A (en) * 1983-02-28 1984-07-17 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
US4533661A (en) * 1983-03-28 1985-08-06 E. R. Squibb & Sons, Inc. Certain 3-phosphinyl-amino-2-oxo-1H-azepine-1-acetic acid derivatives having anti-hypertensive activity
US4567167A (en) * 1983-03-28 1986-01-28 E. R. Squibb & Sons, Inc. Certain 3-phosphinyl-2-oxo-piperidine-1-acetic acid derivatives having anti-hypertensive activity
US4598071A (en) * 1983-03-28 1986-07-01 E. R. Squibb & Sons, Inc. Certain 3-phosphinyl-amino-2-oxo-1H-azocine or azonine-1-acetic acid derivatives having anti-hypertensive properties
US4474778A (en) * 1983-11-09 1984-10-02 E. R. Squibb & Sons, Inc. Lactam containing compounds, their pharmaceutical compositions and method of use
JPH0637473B2 (ja) * 1985-10-11 1994-05-18 三共株式会社 ラクタム化合物
FI90418C (fi) * 1986-04-04 1994-02-10 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten perhydrotiatsepiini- ja perhydroatsepiinijohdannaisten valmistamiseksi
IT1206078B (it) * 1987-06-03 1989-04-14 Polifarma Spa Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
EP1395560A1 (fr) 2001-05-23 2004-03-10 Ucb, S.A. Derives d'acide alcanoique 2-oxo-piperidinyl- et 2-oxo-azepanyle destines au traitement de l'epilepsie et d'autres troubles neurologiques
US20090149673A1 (en) * 2007-12-05 2009-06-11 Semprus Biosciences Corp. Synthetic non-fouling amino acids
US10350223B2 (en) 2015-03-03 2019-07-16 Richard W. Yee Compositions and methods for treating ocular diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4192875A (en) * 1979-02-02 1980-03-11 Merck & Co., Inc. Cyclic hexapeptide
US4377515A (en) * 1979-10-01 1983-03-22 Merck & Co., Inc. Long lasting agonists and antagonists of LH-RH

Also Published As

Publication number Publication date
EP0046291A3 (en) 1982-04-14
GR74635B (fr) 1984-06-29
ES504791A0 (es) 1983-04-01
PT73537A (en) 1981-09-01
EP0046291A2 (fr) 1982-02-24
PT73537B (en) 1983-07-04
ES8403460A1 (es) 1984-03-16
ES519057A0 (es) 1984-03-16
EP0046291B1 (fr) 1985-12-27
DE3173304D1 (en) 1986-02-06
ES8305337A1 (es) 1983-04-01

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Legal Events

Date Code Title Description
ATS Application withdrawn