DK3572515T3 - Glykoproteinhormon langtidsvirkende superagonister - Google Patents
Glykoproteinhormon langtidsvirkende superagonister Download PDFInfo
- Publication number
- DK3572515T3 DK3572515T3 DK19170014.5T DK19170014T DK3572515T3 DK 3572515 T3 DK3572515 T3 DK 3572515T3 DK 19170014 T DK19170014 T DK 19170014T DK 3572515 T3 DK3572515 T3 DK 3572515T3
- Authority
- DK
- Denmark
- Prior art keywords
- superagonists
- glycoprotein hormone
- term effective
- long
- hormone long
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 230000007774 longterm Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261677331P | 2012-07-30 | 2012-07-30 | |
| EP13826476.7A EP2880164B1 (en) | 2012-07-30 | 2013-07-29 | Glycoprotein hormone long-acting superagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3572515T3 true DK3572515T3 (da) | 2021-10-11 |
Family
ID=49995487
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13826476.7T DK2880164T3 (da) | 2012-07-30 | 2013-07-29 | Glykoproteinhormon langstidsvirkende superagonister |
| DK19170014.5T DK3572515T3 (da) | 2012-07-30 | 2013-07-29 | Glykoproteinhormon langtidsvirkende superagonister |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13826476.7T DK2880164T3 (da) | 2012-07-30 | 2013-07-29 | Glykoproteinhormon langstidsvirkende superagonister |
Country Status (21)
| Country | Link |
|---|---|
| US (5) | US9187545B2 (da) |
| EP (4) | EP3572515B1 (da) |
| JP (1) | JP6429774B2 (da) |
| CN (3) | CN112458096A (da) |
| AR (1) | AR091936A1 (da) |
| AU (2) | AU2013296709B2 (da) |
| BR (1) | BR112015001885B1 (da) |
| CA (2) | CA3108181A1 (da) |
| DK (2) | DK2880164T3 (da) |
| ES (2) | ES2894135T3 (da) |
| HR (1) | HRP20190847T1 (da) |
| HU (1) | HUE044016T2 (da) |
| MX (1) | MX360717B (da) |
| NZ (1) | NZ707016A (da) |
| PL (2) | PL2880164T3 (da) |
| PT (2) | PT2880164T (da) |
| RS (1) | RS58881B1 (da) |
| RU (2) | RU2668174C2 (da) |
| UA (1) | UA118653C2 (da) |
| WO (1) | WO2014022283A2 (da) |
| ZA (1) | ZA201502778B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10457713B2 (en) | 2012-07-30 | 2019-10-29 | Trophogen, Inc. | Glycoprotein hormone long-acting superagonists |
| AU2013296709B2 (en) | 2012-07-30 | 2018-03-08 | Trophogen Inc. | Glycoprotein hormone long-acting superagonists |
| CA2929561A1 (en) | 2013-11-05 | 2015-05-14 | Trophogen Inc. | Glycoprotein hormone long-acting superagonists |
| BR102015032660B1 (pt) | 2015-12-28 | 2019-05-28 | Ouro Fino Saúde Animal Participações S.A. | PROCESSO DE PRODUÇÃO DE UMA GONADOTROFINA CORIÔNICA EQUINA RECOMBINANTE (reCG): COMPOSIÇÃO VETERINÁRIA E USO |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196123A (en) | 1978-11-20 | 1980-04-01 | Eugenia Rosemberg | Hybrid chorionic gonadotropin preparations and methods for stimulating ovulation using same |
| EP0161063B1 (en) | 1984-04-03 | 1991-07-24 | Serono Laboratories, Inc. | Method of inducing ovulation |
| US5008050A (en) | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
| US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| EP0290644B1 (en) | 1987-05-12 | 1995-11-15 | Serono Pharmazeutische Präparate GmbH | Subcutaneous administration of human chorionic gonadotrophin |
| US5017566A (en) | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
| US6018026A (en) | 1988-01-22 | 2000-01-25 | Zymogenetics, Inc. | Biologically active dimerized and multimerized polypeptide fusions |
| AU4076589A (en) | 1988-09-01 | 1990-04-02 | Applied Research Systems Ars Holding N.V. | Methods for producing gonadotropin and tsh super-agonists |
| GB8901778D0 (en) | 1989-01-27 | 1989-03-15 | Univ Court Of The University O | Manipulatory technique |
| US6225449B1 (en) | 1991-10-04 | 2001-05-01 | Washington University | Hormone analogs with multiple CTP extensions |
| EP0404458A3 (en) | 1989-06-19 | 1992-03-04 | Bunge (Australia) Proprietary Limited | Ovine follicle stimulating hormone |
| DE69131978T2 (de) | 1990-05-08 | 2000-10-05 | Univ New Jersey Med | Glykoproteinhormon-analoga mit veränderten immunologischen merkmalen, veränderter wirksamkeit und/oder rezeptorspezifität |
| WO1992002244A1 (en) | 1990-07-31 | 1992-02-20 | The Liposome Company, Inc. | Accumulation of amino acids and peptides into liposomes |
| US5612034A (en) | 1990-10-03 | 1997-03-18 | Redcell, Inc. | Super-globuling for in vivo extended lifetimes |
| WO1993019202A2 (en) | 1992-03-10 | 1993-09-30 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Exchangeable template reaction |
| US5604198A (en) | 1994-05-12 | 1997-02-18 | Poduslo; Joseph F. | Method to enhance permeability of the blood/brain blood/nerve barriers to therapeutic agents |
| RU2213099C2 (ru) * | 1994-08-12 | 2003-09-27 | Вашингтон Юниверсити | Одноцепочечный белок, модулятор гормонов лютеинизирующего, фолликулостимулирующего, тиреостимулирующего и хорионического гонадотропина (варианты), молекула нуклеиновой кислоты (варианты), вектор (варианты), линия трансформированных клеток сно (варианты), способ продуцирования одноцепочечного белка (варианты) |
| US6020473A (en) | 1995-08-25 | 2000-02-01 | Genentech, Inc. | Nucleic acids encoding variants of vascular endothelial cell growth factor |
| US7005505B1 (en) | 1995-08-25 | 2006-02-28 | Genentech, Inc. | Variants of vascular endothelial cell growth factor |
| US6596712B2 (en) | 1996-04-26 | 2003-07-22 | Genaera Corporation | Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities |
| EP1947117B1 (en) | 1996-05-08 | 2013-07-17 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Glycoprotein hormone superagonists |
| US6361992B1 (en) * | 1996-05-08 | 2002-03-26 | The United States Of America As Represented By The Department Of Health And Human Services | Thyroid stimulating hormone superagonists |
| JP2001517075A (ja) | 1996-08-23 | 2001-10-02 | ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ | 組換え血管内皮細胞増殖因子ｄ（ｖｅｇｆ―ｄ） |
| JP2002511732A (ja) | 1996-10-11 | 2002-04-16 | ザ・テキサス・エイ・アンド・エム・ユニヴァーシティ・システム | トランスジェニック動物を発生させるための組成物および方法 |
| US6750044B1 (en) | 1996-10-17 | 2004-06-15 | Genentech, Inc. | Variants of vascular endothelial cell growth factor having antagonistic properties, nucleic acids encoding the same and host cells comprising those nucleic acids |
| US6485942B1 (en) | 1997-02-14 | 2002-11-26 | Genentech, Inc. | Variants of vascular endothelial cell growth factor having altered pharmacological properties, and recombinant methods of production |
| US6080912A (en) | 1997-03-20 | 2000-06-27 | Wisconsin Alumni Research Foundation | Methods for creating transgenic animals |
| JP3950484B2 (ja) * | 1997-06-25 | 2007-08-01 | アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ | ジスルフィド架橋結合した糖タンパク質ホルモン類似体類およびそれらの調製および使用 |
| US6281408B1 (en) | 1998-02-20 | 2001-08-28 | Thomas Jefferson University | Efficient method for production of compound transgenic animals |
| CA2344277A1 (en) | 1998-09-22 | 2000-03-30 | University Of Maryland, Baltimore | Cystine knot growth factor mutants |
| DE69931178T8 (de) | 1998-11-02 | 2007-06-28 | Ludwig Institute For Cancer Research | Ein dem vaskularen endothelen wachstumsfaktor verwandtes protein aus orf virus nz10 bindet und aktiviert den säuger vegf rezeptor-2 |
| US7112341B1 (en) * | 1999-04-13 | 2006-09-26 | Nektar Therapeutics | Pulmonary administration of dry powder formulations for treating infertility |
| CA2373822A1 (en) | 1999-05-20 | 2000-11-30 | Scios Inc. | Vascular endothelial growth factor variants |
| US6555660B2 (en) | 2000-01-10 | 2003-04-29 | Maxygen Holdings Ltd. | G-CSF conjugates |
| US20020127652A1 (en) | 2000-02-11 | 2002-09-12 | Schambye Hans Thalsgard | Follicle stimulating hormones |
| JP4689956B2 (ja) | 2001-08-01 | 2011-06-01 | ユニバーシティ オブ ブリストル | 増殖因子イソ型 |
| US20070184023A1 (en) | 2003-10-30 | 2007-08-09 | Pharmexa A/S | Method for down-regulation of vegf |
| AU2004287645A1 (en) * | 2003-11-06 | 2005-05-19 | Compugen Ltd. | Variants of human glycoprotein hormone alpha chain: compositions and uses thereof |
| US8067368B2 (en) | 2004-01-27 | 2011-11-29 | The Ohio State University Research Foundation | Vascular endothelial growth factors and methods of their use |
| AU2005223651B2 (en) * | 2004-03-19 | 2012-07-12 | Trophogen, Inc. | Follicle stimulating hormone superagonists |
| BRPI0509469A (pt) | 2004-03-31 | 2007-09-11 | Trophogen Inc | superagonistas do hormÈnio glicoprotéico humano e uso dos mesmos |
| CN101067118A (zh) * | 2007-04-24 | 2007-11-07 | 新疆农业科学院微生物应用研究所 | 一种重组牛促卵泡激素在毕赤酵母中的表达 |
| WO2011075606A2 (en) * | 2009-12-18 | 2011-06-23 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| WO2012016576A1 (en) * | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
| AU2013296709B2 (en) | 2012-07-30 | 2018-03-08 | Trophogen Inc. | Glycoprotein hormone long-acting superagonists |
| US9905908B2 (en) | 2014-01-14 | 2018-02-27 | Luxshare Precision Industry Co., Ltd. | Antenna structure with proximity sensor |
-
2013
- 2013-07-29 AU AU2013296709A patent/AU2013296709B2/en active Active
- 2013-07-29 PT PT13826476T patent/PT2880164T/pt unknown
- 2013-07-29 CN CN202011095353.6A patent/CN112458096A/zh active Pending
- 2013-07-29 WO PCT/US2013/052510 patent/WO2014022283A2/en active Application Filing
- 2013-07-29 DK DK13826476.7T patent/DK2880164T3/da active
- 2013-07-29 CN CN202011090733.0A patent/CN112409472A/zh active Pending
- 2013-07-29 EP EP19170014.5A patent/EP3572515B1/en active Active
- 2013-07-29 CA CA3108181A patent/CA3108181A1/en active Pending
- 2013-07-29 MX MX2015001414A patent/MX360717B/es active IP Right Grant
- 2013-07-29 RU RU2015103059A patent/RU2668174C2/ru active
- 2013-07-29 EP EP19166115.6A patent/EP3533874A1/en not_active Withdrawn
- 2013-07-29 ES ES19170014T patent/ES2894135T3/es active Active
- 2013-07-29 BR BR112015001885-8A patent/BR112015001885B1/pt active IP Right Grant
- 2013-07-29 RS RS20190625A patent/RS58881B1/sr unknown
- 2013-07-29 HU HUE13826476A patent/HUE044016T2/hu unknown
- 2013-07-29 RU RU2018132561A patent/RU2018132561A/ru not_active Application Discontinuation
- 2013-07-29 EP EP13826476.7A patent/EP2880164B1/en active Active
- 2013-07-29 PT PT19170014T patent/PT3572515T/pt unknown
- 2013-07-29 UA UAA201500722A patent/UA118653C2/uk unknown
- 2013-07-29 ES ES13826476T patent/ES2727659T3/es active Active
- 2013-07-29 PL PL13826476T patent/PL2880164T3/pl unknown
- 2013-07-29 CN CN201380047511.2A patent/CN104619846B/zh active Active
- 2013-07-29 NZ NZ707016A patent/NZ707016A/en active IP Right Revival
- 2013-07-29 DK DK19170014.5T patent/DK3572515T3/da active
- 2013-07-29 PL PL19170014T patent/PL3572515T3/pl unknown
- 2013-07-29 JP JP2015525484A patent/JP6429774B2/ja active Active
- 2013-07-29 CA CA2880520A patent/CA2880520C/en active Active
- 2013-07-29 EP EP21186472.3A patent/EP4012033A1/en active Pending
- 2013-07-30 AR ARP130102702A patent/AR091936A1/es unknown
- 2013-07-30 US US13/954,690 patent/US9187545B2/en active Active
-
2014
- 2014-06-19 US US14/309,317 patent/US9249205B2/en active Active
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2015
- 2015-04-23 ZA ZA2015/02778A patent/ZA201502778B/en unknown
- 2015-08-20 US US14/831,124 patent/US10766941B2/en active Active
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2018
- 2018-05-31 AU AU2018203815A patent/AU2018203815B2/en active Active
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2019
- 2019-05-07 HR HRP20190847TT patent/HRP20190847T1/hr unknown
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2020
- 2020-09-04 US US17/012,387 patent/US20210054041A1/en active Pending
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2023
- 2023-04-05 US US18/296,005 patent/US20230357345A1/en active Pending
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