DK3563155T3 - Præfabrikeret mikropartikel til udførelse af en påvisning af en analyt - Google Patents

Præfabrikeret mikropartikel til udførelse af en påvisning af en analyt Download PDF

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Publication number
DK3563155T3
DK3563155T3 DK17832075.0T DK17832075T DK3563155T3 DK 3563155 T3 DK3563155 T3 DK 3563155T3 DK 17832075 T DK17832075 T DK 17832075T DK 3563155 T3 DK3563155 T3 DK 3563155T3
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DK
Denmark
Prior art keywords
analyte
detection
prefabricated microparticle
microparticle
prefabricated
Prior art date
Application number
DK17832075.0T
Other languages
English (en)
Inventor
Katrin Steinmetzer
Thomas Ellinger
Eugen Ermantraut
Stephan Hubold
Torsten Schulz
Original Assignee
Blink Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blink Ag filed Critical Blink Ag
Application granted granted Critical
Publication of DK3563155T3 publication Critical patent/DK3563155T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6848Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK17832075.0T 2016-12-30 2017-12-22 Præfabrikeret mikropartikel til udførelse af en påvisning af en analyt DK3563155T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16207455.3A EP3343223A1 (en) 2016-12-30 2016-12-30 A prefabricated microparticle for performing a digital detection of an analyte
PCT/EP2017/084370 WO2018122162A1 (en) 2016-12-30 2017-12-22 A prefabricated microparticle for performing a detection of an analyte

Publications (1)

Publication Number Publication Date
DK3563155T3 true DK3563155T3 (da) 2022-10-31

Family

ID=57749771

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17832075.0T DK3563155T3 (da) 2016-12-30 2017-12-22 Præfabrikeret mikropartikel til udførelse af en påvisning af en analyt

Country Status (8)

Country Link
US (1) US11073518B2 (da)
EP (3) EP3343223A1 (da)
JP (2) JP7228901B2 (da)
AU (1) AU2017385533A1 (da)
CA (1) CA3048761A1 (da)
DK (1) DK3563155T3 (da)
ES (1) ES2928749T3 (da)
WO (1) WO2018122162A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3839508A1 (en) * 2019-12-16 2021-06-23 Blink AG A method of detecting and/or quantitating an analyte of interest in a plurality of biological liquid samples
EP3839509A1 (en) * 2019-12-16 2021-06-23 Blink AG A library of prefabricated microparticles and precursors thereof
JP7445966B2 (ja) 2020-03-24 2024-03-08 国立研究開発法人産業技術総合研究所 糖鎖を解析する方法
EP4100545A4 (en) * 2020-04-29 2023-06-21 Hewlett-Packard Development Company, L.P. NUCLEIC ACID AMPLIFICATION
EP4252907A1 (en) 2022-03-30 2023-10-04 Blink AG A method for arranging microspheres in a non-aqueous liquid phase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60211857T2 (de) 2001-02-23 2006-12-21 Japan Science And Technology Agency, Kawaguchi Verfahren zur herstellung einer emulsion und vorrichtung dafür
US6806058B2 (en) 2001-05-26 2004-10-19 One Cell Systems, Inc. Secretions of proteins by encapsulated cells
CA2560272C (en) 2004-03-23 2012-05-08 Japan Science And Technology Agency Method and apparatus for producing microdroplets
JP2008245612A (ja) 2007-03-30 2008-10-16 Hitachi Ltd 試料調製法および装置
DK2396405T3 (da) * 2009-02-11 2017-02-06 Univ Rochester Rumligt uhomogent funktionaliserede porøse medier og fremgangsmåde til anvendelse ved selektiv fjernelse af kontaminanter
WO2011100057A2 (en) * 2010-02-09 2011-08-18 Eugene Spier Methods and compositions for universal detection of nucleic acids
US9562897B2 (en) 2010-09-30 2017-02-07 Raindance Technologies, Inc. Sandwich assays in droplets
WO2013024821A1 (ja) 2011-08-12 2013-02-21 国立大学法人筑波大学 並列反応用懸濁液、並列反応方法およびスクリーニング方法
US20150293102A1 (en) * 2013-04-13 2015-10-15 Jung-Uk Shim Detecting low-abundant analyte in microfluidic droplets
CA2959978A1 (en) * 2013-09-24 2015-04-02 The Regents Of The University Of California Encapsulated sensors and sensing systems for bioassays and diagnostics and methods for making and using them

Also Published As

Publication number Publication date
EP3563155B1 (en) 2022-07-27
US20190331677A1 (en) 2019-10-31
CA3048761A1 (en) 2018-07-05
WO2018122162A1 (en) 2018-07-05
JP2023001342A (ja) 2023-01-04
JP7228901B2 (ja) 2023-02-27
EP4123305A1 (en) 2023-01-25
EP3563155A1 (en) 2019-11-06
US11073518B2 (en) 2021-07-27
ES2928749T3 (es) 2022-11-22
JP2020503893A (ja) 2020-02-06
US20210318303A1 (en) 2021-10-14
EP3343223A1 (en) 2018-07-04
AU2017385533A1 (en) 2019-07-11

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