DK353584A - Fremgangsmaade til omdannelse af en ester til den tilsvarende carboxylsyre - Google Patents

Fremgangsmaade til omdannelse af en ester til den tilsvarende carboxylsyre Download PDF

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Publication number
DK353584A
DK353584A DK353584A DK353584A DK353584A DK 353584 A DK353584 A DK 353584A DK 353584 A DK353584 A DK 353584A DK 353584 A DK353584 A DK 353584A DK 353584 A DK353584 A DK 353584A
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DK
Denmark
Prior art keywords
ester
converting
procedure
carboxylic acid
similar carboxylic
Prior art date
Application number
DK353584A
Other languages
English (en)
Other versions
DK166283C (da
DK166283B (da
DK353584D0 (da
Inventor
Jack Wayne Fisher
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK353584D0 publication Critical patent/DK353584D0/da
Publication of DK353584A publication Critical patent/DK353584A/da
Publication of DK166283B publication Critical patent/DK166283B/da
Application granted granted Critical
Publication of DK166283C publication Critical patent/DK166283C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02Preparation
    • C07D463/06Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D463/08Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • C07D477/06Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D477/08Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04Preparation
    • C07D499/08Modification of a carboxyl radical directly attached in position 2, e.g. esterification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK353584A 1983-07-22 1984-07-19 Fremgangsmaade til omdannelse af en ester af et penicillin eller cephalosporin eller en kerneanalog deraf til den tilsvarende carboxylsyre DK166283C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51621983A 1983-07-22 1983-07-22
US51621983 1983-07-22

Publications (4)

Publication Number Publication Date
DK353584D0 DK353584D0 (da) 1984-07-19
DK353584A true DK353584A (da) 1985-01-23
DK166283B DK166283B (da) 1993-03-29
DK166283C DK166283C (da) 1993-08-30

Family

ID=24054622

Family Applications (1)

Application Number Title Priority Date Filing Date
DK353584A DK166283C (da) 1983-07-22 1984-07-19 Fremgangsmaade til omdannelse af en ester af et penicillin eller cephalosporin eller en kerneanalog deraf til den tilsvarende carboxylsyre

Country Status (11)

Country Link
EP (1) EP0132987B1 (da)
JP (1) JPS6048936A (da)
KR (1) KR870001271B1 (da)
CA (1) CA1218646A (da)
DE (1) DE3466221D1 (da)
DK (1) DK166283C (da)
GB (1) GB2143529B (da)
GR (1) GR79944B (da)
HU (1) HU197017B (da)
IE (1) IE57901B1 (da)
IL (1) IL72412A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302711A (en) * 1992-02-18 1994-04-12 Eli Lilly And Company Ester cleavage process for use with β-lactams
DE907654T1 (de) * 1995-11-06 1999-09-16 Gist-Brocades B.V. Verfahren zur de-esterifikation
DE69609636D1 (de) * 1995-11-06 2000-09-07 Dsm Nv Verfahren zur de-esterifikation
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
WO2020129877A1 (ja) * 2018-12-18 2020-06-25 株式会社デ・ウエスタン・セラピテクス研究所 イソキノリンスルホニルクロリド酸付加塩及びその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52106891A (en) * 1976-03-03 1977-09-07 Shionogi & Co Ltd Removal of carboxyl protecting group
IL52144A (en) * 1976-07-01 1979-10-31 Lilly Co Eli De-esterification process for -lactam antibiotic esters

Also Published As

Publication number Publication date
IL72412A0 (en) 1984-11-30
KR850001219A (ko) 1985-03-16
GB2143529A (en) 1985-02-13
GB2143529B (en) 1986-12-17
IE57901B1 (en) 1993-05-05
IE841870L (en) 1985-01-22
EP0132987B1 (en) 1987-09-16
CA1218646A (en) 1987-03-03
GR79944B (da) 1984-10-31
DE3466221D1 (en) 1987-10-22
DK166283C (da) 1993-08-30
DK166283B (da) 1993-03-29
EP0132987A1 (en) 1985-02-13
DK353584D0 (da) 1984-07-19
IL72412A (en) 1988-05-31
KR870001271B1 (ko) 1987-06-30
HU197017B (en) 1989-02-28
HUT38356A (en) 1986-05-28
GB8418170D0 (en) 1984-08-22
JPS6048936A (ja) 1985-03-16

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