DK3502112T3 - Anti-influenza virus pyrimidinderivat - Google Patents
Anti-influenza virus pyrimidinderivatInfo
- Publication number
- DK3502112T3 DK3502112T3 DK17845565.5T DK17845565T DK3502112T3 DK 3502112 T3 DK3502112 T3 DK 3502112T3 DK 17845565 T DK17845565 T DK 17845565T DK 3502112 T3 DK3502112 T3 DK 3502112T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrimide
- derivative
- influenza virus
- influenza
- virus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610804101 | 2016-09-05 | ||
| CN201611238759 | 2016-12-28 | ||
| PCT/CN2017/100461 WO2018041263A1 (zh) | 2016-09-05 | 2017-09-05 | 抗流感病毒嘧啶衍生物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3502112T3 true DK3502112T3 (da) | 2025-09-22 |
Family
ID=61300177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17845565.5T DK3502112T3 (da) | 2016-09-05 | 2017-09-05 | Anti-influenza virus pyrimidinderivat |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US11136319B2 (enExample) |
| EP (1) | EP3502112B1 (enExample) |
| JP (1) | JP6838773B2 (enExample) |
| KR (1) | KR102312088B1 (enExample) |
| CN (3) | CN110627784B (enExample) |
| AU (1) | AU2017320088B2 (enExample) |
| CA (1) | CA3035680C (enExample) |
| DK (1) | DK3502112T3 (enExample) |
| IL (1) | IL265166B (enExample) |
| MX (1) | MX394277B (enExample) |
| RU (1) | RU2727772C1 (enExample) |
| SG (1) | SG11201901894TA (enExample) |
| WO (1) | WO2018041263A1 (enExample) |
| ZA (1) | ZA201901886B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018033082A1 (en) | 2016-08-16 | 2018-02-22 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| WO2018041091A1 (en) | 2016-08-30 | 2018-03-08 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| US11136319B2 (en) * | 2016-09-05 | 2021-10-05 | Guangdong Raynovent Biotech Co., Ltd. | Anti-influenza virus pyrimidine derivative |
| US10987354B2 (en) | 2016-12-15 | 2021-04-27 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| WO2018127096A1 (en) * | 2017-01-05 | 2018-07-12 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| WO2018157830A1 (en) | 2017-03-02 | 2018-09-07 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| US11535613B2 (en) | 2018-03-05 | 2022-12-27 | Guangdong Raynovent Biotech Co., Ltd. | Crystal form and salt form of pyridoimidazole compound and preparation method therefor |
| CN110590768B (zh) * | 2018-06-13 | 2021-02-26 | 银杏树药业(苏州)有限公司 | 杂环化合物、其组合物及其作为抗流感病毒药物的应用 |
| CN114127068B (zh) * | 2019-07-22 | 2024-05-28 | 广东众生睿创生物科技有限公司 | 嘧啶衍生物的优势盐型及其晶型 |
| CN114502150B (zh) * | 2019-09-10 | 2023-03-24 | 广东众生睿创生物科技有限公司 | 一种用于治疗病毒性感冒的药物组合物及其制剂 |
| CN111454166B (zh) * | 2019-12-30 | 2021-02-26 | 广东莱佛士制药技术有限公司 | 制备(2s,3s)-3-氨基-二环[2.2.2]辛烷-2-甲酸酯的方法 |
| CN113116899B (zh) * | 2020-03-06 | 2022-12-20 | 广东众生睿创生物科技有限公司 | 一种用于治疗流感的药物组合物及含有该药物组合物的制剂 |
| CN116323593B (zh) * | 2020-10-29 | 2025-06-03 | 广东众生睿创生物科技有限公司 | 一种嘧啶衍生物的晶型及其制备方法 |
| CN114569562B (zh) * | 2020-12-01 | 2025-07-29 | 南通诺泰生物医药技术有限公司 | 一种抗流感病毒的药物组合物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101903354B1 (ko) * | 2009-06-17 | 2018-10-04 | 버텍스 파마슈티칼스 인코포레이티드 | 인플루엔자 바이러스 복제의 억제제 |
| EP2651940A1 (en) | 2010-12-16 | 2013-10-23 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| US20130102600A1 (en) * | 2011-10-21 | 2013-04-25 | F. Hoffmann-La Roche Ltd | Heteroaryl hydroxamic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease |
| KR102488479B1 (ko) * | 2014-08-08 | 2023-01-12 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 인플루엔자 바이러스 감염에 사용하기 위한 인돌 |
| CN109748915B (zh) * | 2015-12-09 | 2021-03-26 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
| WO2017133657A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | Pyridine and pyrimidine derivatives and their use in treatment, amelioration or prevention of influenza |
| WO2017133670A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | Pyridine and pyrimidine derivatives and their use in treatment, amelioration or prevention of influenza |
| WO2018033082A1 (en) | 2016-08-16 | 2018-02-22 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| US11136319B2 (en) * | 2016-09-05 | 2021-10-05 | Guangdong Raynovent Biotech Co., Ltd. | Anti-influenza virus pyrimidine derivative |
| US11535613B2 (en) * | 2018-03-05 | 2022-12-27 | Guangdong Raynovent Biotech Co., Ltd. | Crystal form and salt form of pyridoimidazole compound and preparation method therefor |
| CN114127068B (zh) * | 2019-07-22 | 2024-05-28 | 广东众生睿创生物科技有限公司 | 嘧啶衍生物的优势盐型及其晶型 |
-
2017
- 2017-09-05 US US16/330,353 patent/US11136319B2/en active Active
- 2017-09-05 CN CN201910800685.0A patent/CN110627784B/zh active Active
- 2017-09-05 RU RU2019109246A patent/RU2727772C1/ru active
- 2017-09-05 DK DK17845565.5T patent/DK3502112T3/da active
- 2017-09-05 JP JP2019512638A patent/JP6838773B2/ja active Active
- 2017-09-05 SG SG11201901894TA patent/SG11201901894TA/en unknown
- 2017-09-05 KR KR1020197009275A patent/KR102312088B1/ko active Active
- 2017-09-05 AU AU2017320088A patent/AU2017320088B2/en active Active
- 2017-09-05 WO PCT/CN2017/100461 patent/WO2018041263A1/zh not_active Ceased
- 2017-09-05 CN CN201780054195.XA patent/CN109790159B/zh active Active
- 2017-09-05 CN CN201910800902.6A patent/CN110623958B/zh active Active
- 2017-09-05 MX MX2019002541A patent/MX394277B/es unknown
- 2017-09-05 EP EP17845565.5A patent/EP3502112B1/en active Active
- 2017-09-05 CA CA3035680A patent/CA3035680C/en active Active
-
2019
- 2019-03-04 IL IL265166A patent/IL265166B/en unknown
- 2019-03-27 ZA ZA2019/01886A patent/ZA201901886B/en unknown
-
2021
- 2021-08-24 US US17/410,801 patent/US11725009B2/en active Active
-
2023
- 2023-06-19 US US18/337,329 patent/US12319692B2/en active Active
-
2025
- 2025-04-28 US US19/191,976 patent/US20250250275A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3502112T3 (da) | Anti-influenza virus pyrimidinderivat | |
| DK3805376T3 (da) | Modificeret virus | |
| DK3565568T3 (da) | Ændret virus | |
| EP3417133C0 (en) | HINGE | |
| DK3642202T3 (da) | Dihydro-pyrrolo-pyridin-derivater | |
| UA32259S (uk) | Розприскувач | |
| EP3219592C0 (de) | Halterung | |
| EP3546462A4 (en) | NEW OXOISOQUINOLINE DERIVATIVE | |
| LT3402792T (lt) | Chinolin-2-ono dariniai | |
| LT3457851T (lt) | Sobetiromo dariniai | |
| EP3564216A4 (en) | PYRIMIDINE DERIVATIVE | |
| EP3302376A4 (en) | NASAL DILATORS | |
| LT3371168T (lt) | Indolin-2-ono dariniai | |
| EP3490365A4 (en) | CORN | |
| DK3407944T3 (da) | Forstøver | |
| FI20165867A7 (fi) | Valoherkiste | |
| EP3437644A4 (en) | MEDICINE | |
| EP3333163A4 (en) | SUBSTITUTED GUANIDINE DERIVATIVE | |
| EP3554717C0 (de) | Sprühgerät | |
| EP3444345C0 (en) | MICRO-143 RNA DERIVATIVE | |
| EP3527216A4 (en) | Medicine | |
| EP3357916A4 (en) | benzamide | |
| DK3645513T3 (da) | Benzazepinderivater | |
| EP3590944A4 (en) | AZETIDINE DERIVATIVE | |
| EP3339541C0 (de) | Faltanlage |