DK3481827T3 - Imidazo[1,2-a]pyridinderivater, fremgangsmåder til fremstilling og anvendelse deraf - Google Patents
Imidazo[1,2-a]pyridinderivater, fremgangsmåder til fremstilling og anvendelse deraf Download PDFInfo
- Publication number
- DK3481827T3 DK3481827T3 DK17824485.1T DK17824485T DK3481827T3 DK 3481827 T3 DK3481827 T3 DK 3481827T3 DK 17824485 T DK17824485 T DK 17824485T DK 3481827 T3 DK3481827 T3 DK 3481827T3
- Authority
- DK
- Denmark
- Prior art keywords
- imidazo
- manufacturing methods
- pyridine derivatives
- pyridine
- derivatives
- Prior art date
Links
- 150000005234 imidazo[1,2-a]pyridines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160085048A KR101777971B1 (ko) | 2016-07-05 | 2016-07-05 | 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도 |
| PCT/KR2017/007055 WO2018008929A1 (en) | 2016-07-05 | 2017-07-04 | Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3481827T3 true DK3481827T3 (da) | 2021-12-06 |
Family
ID=59926389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17824485.1T DK3481827T3 (da) | 2016-07-05 | 2017-07-04 | Imidazo[1,2-a]pyridinderivater, fremgangsmåder til fremstilling og anvendelse deraf |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10696671B2 (da) |
| EP (1) | EP3481827B1 (da) |
| JP (1) | JP6713556B2 (da) |
| KR (1) | KR101777971B1 (da) |
| CN (1) | CN109415362B (da) |
| AU (1) | AU2017293271C1 (da) |
| CA (1) | CA3029745C (da) |
| DK (1) | DK3481827T3 (da) |
| ES (1) | ES2900305T3 (da) |
| HU (1) | HUE057549T2 (da) |
| IL (1) | IL264075B (da) |
| MX (1) | MX383309B (da) |
| MY (1) | MY196082A (da) |
| NZ (1) | NZ749346A (da) |
| PH (1) | PH12019500015A1 (da) |
| PL (1) | PL3481827T3 (da) |
| PT (1) | PT3481827T (da) |
| RU (1) | RU2725147C1 (da) |
| SA (1) | SA519400792B1 (da) |
| SG (1) | SG11201811221XA (da) |
| WO (1) | WO2018008929A1 (da) |
| ZA (1) | ZA201900236B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101777971B1 (ko) | 2016-07-05 | 2017-09-12 | 제일약품주식회사 | 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도 |
| KR20190057569A (ko) * | 2017-11-20 | 2019-05-29 | 제일약품주식회사 | 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도 |
| EP3955927A4 (en) * | 2019-04-18 | 2023-06-07 | Thomas Julius Borody | COMPOSITIONS AND METHODS FOR TREATING, AMOUNTING AND PREVENTING H. PYLORI INFECTIONS |
| KR102496869B1 (ko) | 2022-07-29 | 2023-02-07 | 제일약품주식회사 | 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법 |
| EP4628081A1 (en) | 2022-11-29 | 2025-10-08 | Jeil Pharmaceutical Co., Ltd. | Composition for removing helicobacter pylori comprising zastaprazan or pharmaceutically acceptable salt thereof |
| JP2025538641A (ja) * | 2022-11-29 | 2025-11-28 | ジェイル・ファーマシューティカル・シーオー・エルティーディー | ザスタプラザンまたはこの薬剤学的に許容される塩を含むヘリコバクター・ピロリ除菌用組成物 |
| WO2024117797A1 (ko) | 2022-11-29 | 2024-06-06 | 제일약품 주식회사 | 자스타프라잔 또는 이의 약제학적으로 허용되는 염을 포함하는 약제 연관 소화성 궤양의 예방 또는 치료용 약학적 조성물 |
| PE20260034A1 (es) | 2023-02-01 | 2026-01-09 | Jeil Pharmaceutical Co Ltd | Formulacion farmaceutica, metodo de preparacion para la misma y composicion de tableta |
| TW202432120A (zh) * | 2023-02-01 | 2024-08-16 | 韓商安康尼克治療有限公司 | 注射用組合物、包含其之醫藥調配物以及製備該組合物之方法 |
| TW202535382A (zh) * | 2023-11-29 | 2025-09-16 | 南韓商第一藥品股份有限公司 | 包含ｚａｓｔａｐｒａｚａｎ或其醫藥上可接受的鹽之用於幽門螺旋桿菌根除的組成物 |
| WO2025215593A1 (en) * | 2024-04-12 | 2025-10-16 | Hetero Labs Limited | An improved process for preparation of zastaprazan |
| CN120827558A (zh) * | 2024-04-19 | 2025-10-24 | 丽珠医药集团股份有限公司 | 咪唑并[1,2-a]吡啶衍生物药物组合物及其制备方法和用途 |
| WO2026005545A1 (ko) * | 2024-06-28 | 2026-01-02 | 제일약품주식회사 | 이미다조[1,2-a]피리딘 화합물의 신규 염 및 이의 제조방법 |
| KR20260002254A (ko) | 2024-06-28 | 2026-01-06 | 온코닉테라퓨틱스 주식회사 | 이미다조[1,2-a]피리딘 화합물의 신규 염의 결정형 및 이의 제조방법 |
| CN120117960A (zh) * | 2025-05-12 | 2025-06-10 | 天津全和诚科技有限责任公司 | 一种杂质化合物及其制备方法 |
| CN121248676B (zh) * | 2025-12-04 | 2026-03-06 | 重庆华邦制药有限公司 | 咪唑并[1,2-a]吡啶化合物及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA81219B (en) * | 1980-01-23 | 1982-01-27 | Schering Corp | Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them |
| GB8722488D0 (en) | 1987-09-24 | 1987-10-28 | Fujisawa Pharmaceutical Co | Imidazopyridine compound |
| SE9801526D0 (sv) | 1998-04-29 | 1998-04-29 | Astra Ab | New compounds |
| SE0003186D0 (sv) * | 2000-09-07 | 2000-09-07 | Astrazeneca Ab | New process |
| SE0301904D0 (sv) * | 2003-06-26 | 2003-06-26 | Astrazeneca Ab | Novel imidazopyridine compound II with therapeutic effect |
| WO2006025716A1 (en) | 2004-09-03 | 2006-03-09 | Yuhan Corporation | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof |
| HRP20110473T1 (hr) | 2005-08-30 | 2011-07-31 | Takeda Pharmaceutical Company Limited | Supstituirani derivati 1-heterociklilsulfonil, 2-aminometil, 5-(hetero)-aril 1-h-pirola kao inhibitori kiselinske sekrecije |
| WO2007039464A1 (en) * | 2005-09-22 | 2007-04-12 | Nycomed Gmbh | Isotopically substituted imidazopyridine derivatives for the treatment of gastrointestinal disorders |
| KR101088247B1 (ko) | 2005-12-19 | 2011-11-30 | 라퀄리아 파마 인코포레이티드 | 크로메인 치환된 벤즈이미다졸 및 이들의 산 펌프억제제로서의 용도 |
| WO2008015196A1 (en) * | 2006-07-31 | 2008-02-07 | Nycomed Gmbh | 5-,7-bis-substituted imidazo[1,2-a]pyridines |
| FI20086158A0 (fi) * | 2008-12-03 | 2008-12-03 | Mikael Dahlstroem | Imidatsopyridiinijohdannaiset |
| KR101777971B1 (ko) | 2016-07-05 | 2017-09-12 | 제일약품주식회사 | 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도 |
-
2016
- 2016-07-05 KR KR1020160085048A patent/KR101777971B1/ko active Active
-
2017
- 2017-07-04 MX MX2018016299A patent/MX383309B/es unknown
- 2017-07-04 EP EP17824485.1A patent/EP3481827B1/en active Active
- 2017-07-04 DK DK17824485.1T patent/DK3481827T3/da active
- 2017-07-04 JP JP2018569003A patent/JP6713556B2/ja active Active
- 2017-07-04 MY MYPI2018002377A patent/MY196082A/en unknown
- 2017-07-04 NZ NZ749346A patent/NZ749346A/en unknown
- 2017-07-04 RU RU2019102925A patent/RU2725147C1/ru active
- 2017-07-04 US US16/314,749 patent/US10696671B2/en active Active
- 2017-07-04 WO PCT/KR2017/007055 patent/WO2018008929A1/en not_active Ceased
- 2017-07-04 PT PT178244851T patent/PT3481827T/pt unknown
- 2017-07-04 AU AU2017293271A patent/AU2017293271C1/en active Active
- 2017-07-04 PL PL17824485T patent/PL3481827T3/pl unknown
- 2017-07-04 ES ES17824485T patent/ES2900305T3/es active Active
- 2017-07-04 CN CN201780039504.6A patent/CN109415362B/zh active Active
- 2017-07-04 SG SG11201811221XA patent/SG11201811221XA/en unknown
- 2017-07-04 HU HUE17824485A patent/HUE057549T2/hu unknown
- 2017-07-04 CA CA3029745A patent/CA3029745C/en active Active
-
2019
- 2019-01-02 SA SA519400792A patent/SA519400792B1/ar unknown
- 2019-01-03 IL IL264075A patent/IL264075B/en unknown
- 2019-01-03 PH PH12019500015A patent/PH12019500015A1/en unknown
- 2019-01-14 ZA ZA2019/00236A patent/ZA201900236B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20190152971A1 (en) | 2019-05-23 |
| IL264075B (en) | 2022-02-01 |
| PT3481827T (pt) | 2021-12-09 |
| ES2900305T3 (es) | 2022-03-16 |
| CN109415362A (zh) | 2019-03-01 |
| JP2019524691A (ja) | 2019-09-05 |
| IL264075A (en) | 2019-01-31 |
| MX2018016299A (es) | 2019-08-29 |
| ZA201900236B (en) | 2020-05-27 |
| CN109415362B (zh) | 2021-07-30 |
| BR112018077205A2 (pt) | 2019-04-09 |
| PH12019500015A1 (en) | 2019-10-28 |
| WO2018008929A1 (en) | 2018-01-11 |
| NZ749346A (en) | 2020-04-24 |
| SA519400792B1 (ar) | 2022-09-01 |
| AU2017293271B2 (en) | 2019-12-05 |
| AU2017293271C1 (en) | 2020-04-23 |
| US10696671B2 (en) | 2020-06-30 |
| EP3481827A4 (en) | 2019-11-27 |
| EP3481827B1 (en) | 2021-11-03 |
| RU2725147C1 (ru) | 2020-06-30 |
| JP6713556B2 (ja) | 2020-06-24 |
| HUE057549T2 (hu) | 2022-05-28 |
| PL3481827T3 (pl) | 2022-02-07 |
| CA3029745C (en) | 2020-12-08 |
| KR101777971B1 (ko) | 2017-09-12 |
| CA3029745A1 (en) | 2018-01-11 |
| EP3481827A1 (en) | 2019-05-15 |
| MX383309B (es) | 2025-03-13 |
| SG11201811221XA (en) | 2019-01-30 |
| MY196082A (en) | 2023-03-14 |
| AU2017293271A1 (en) | 2019-01-17 |
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