DK3436034T3 - Muterede bordetella-stammer og fremgangsmåder til brug - Google Patents
Muterede bordetella-stammer og fremgangsmåder til brug Download PDFInfo
- Publication number
- DK3436034T3 DK3436034T3 DK17715426.7T DK17715426T DK3436034T3 DK 3436034 T3 DK3436034 T3 DK 3436034T3 DK 17715426 T DK17715426 T DK 17715426T DK 3436034 T3 DK3436034 T3 DK 3436034T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- bordetella strains
- mutated bordetella
- mutated
- strains
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662314843P | 2016-03-29 | 2016-03-29 | |
| PCT/EP2017/057468 WO2017167834A1 (en) | 2016-03-29 | 2017-03-29 | Mutant bordetella strains and methods for use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3436034T3 true DK3436034T3 (da) | 2025-05-12 |
Family
ID=58488973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17715426.7T DK3436034T3 (da) | 2016-03-29 | 2017-03-29 | Muterede bordetella-stammer og fremgangsmåder til brug |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10682377B2 (enExample) |
| EP (2) | EP4541809A3 (enExample) |
| JP (1) | JP6993984B2 (enExample) |
| CN (2) | CN109069535B (enExample) |
| AU (2) | AU2017242541B2 (enExample) |
| DK (1) | DK3436034T3 (enExample) |
| ES (1) | ES3027194T3 (enExample) |
| FI (1) | FI3436034T3 (enExample) |
| SG (1) | SG11201807783UA (enExample) |
| WO (1) | WO2017167834A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007104451A1 (en) * | 2006-03-10 | 2007-09-20 | Institut Pasteur De Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| CN102448490B (zh) | 2009-04-28 | 2015-05-13 | 国家健康与医学研究院 | 用于预防或治疗过敏原引起的气道疾病的疫苗 |
| US10682377B2 (en) * | 2016-03-29 | 2020-06-16 | Institut Pasteur De Lille | Mutant Bordetella strains and methods of use |
| EP3697439A1 (en) | 2017-10-18 | 2020-08-26 | Institut Pasteur de Lille | Bordetella strains expressing serotype 3 fimbriae |
| AU2021325149A1 (en) | 2020-08-14 | 2023-03-02 | ILiAD Biotechnologies, Inc. | Lyophilized live bordetella vaccines |
| CN116635517A (zh) * | 2020-11-17 | 2023-08-22 | 伊利亚德生物技术有限公司 | 与神经退行性疾病相关的神经病理的治疗和预防 |
| KR20250038747A (ko) | 2022-07-22 | 2025-03-19 | 인스티튜트 내셔날 드 라 싼테 에 드 라 리셰르셰 메디칼르 | 만성 폐쇄성 폐질환의 치료를 위한 보르데텔라 균주의 용도 |
| WO2025257397A1 (en) | 2024-06-14 | 2025-12-18 | Institut National de la Santé et de la Recherche Médicale | Live attenuated bordetella vaccines capable of producing and secreting heterologous antigens |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6713072B1 (en) | 1987-11-02 | 2004-03-30 | Chiron S.R.L. | Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
| GB9115332D0 (en) * | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| FR2718750B1 (fr) | 1994-04-19 | 1996-06-14 | Pasteur Institut | Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants. |
| DE69511392T2 (de) * | 1994-04-28 | 2000-03-23 | Takeda Chemical Industries, Ltd. | Verfahren zur trennung von protektiven verbindungen aus bordetella pertussis |
| FR2754543B1 (fr) | 1996-10-11 | 1998-12-31 | Pasteur Institut | Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires |
| FR2840319B1 (fr) | 2002-05-30 | 2004-08-20 | Pasteur Institut | Souches de bordetella rendues deficientes par attenuation genetique |
| US7582297B2 (en) | 2003-04-11 | 2009-09-01 | Medimmune, Llc | Methods of treating respiratory conditions |
| WO2007104451A1 (en) | 2006-03-10 | 2007-09-20 | Institut Pasteur De Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| US20100111996A1 (en) | 2006-11-15 | 2010-05-06 | Denis Leclerc | Papaya Mosaic Virus-Based Vaccines for Influenza |
| CA2678698A1 (en) | 2007-02-23 | 2008-10-02 | The Penn State Research Foundation | Use of an avirulent bordetella mutant as a live vaccine vector |
| AU2008266910A1 (en) | 2007-06-18 | 2008-12-24 | Hemispherx Biopharma, Inc. | Early intervention of viral infections with immune activators |
| CN102448490B (zh) | 2009-04-28 | 2015-05-13 | 国家健康与医学研究院 | 用于预防或治疗过敏原引起的气道疾病的疫苗 |
| CA2765364C (en) | 2009-06-15 | 2015-05-26 | National University Of Singapore | Influenza vaccine, composition, and methods of use |
| SG10201607233TA (en) * | 2011-11-02 | 2016-10-28 | Univ Singapore | Effect of an attenuated bordetella strain against allergic disease |
| CN102793915B (zh) * | 2012-07-25 | 2013-10-23 | 天津康希诺生物技术有限公司 | 一种无细胞百日咳疫苗的生产方法 |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| US10682377B2 (en) * | 2016-03-29 | 2020-06-16 | Institut Pasteur De Lille | Mutant Bordetella strains and methods of use |
-
2017
- 2017-03-29 US US15/472,436 patent/US10682377B2/en active Active
- 2017-03-29 AU AU2017242541A patent/AU2017242541B2/en active Active
- 2017-03-29 ES ES17715426T patent/ES3027194T3/es active Active
- 2017-03-29 SG SG11201807783UA patent/SG11201807783UA/en unknown
- 2017-03-29 FI FIEP17715426.7T patent/FI3436034T3/fi active
- 2017-03-29 WO PCT/EP2017/057468 patent/WO2017167834A1/en not_active Ceased
- 2017-03-29 DK DK17715426.7T patent/DK3436034T3/da active
- 2017-03-29 JP JP2018551960A patent/JP6993984B2/ja active Active
- 2017-03-29 EP EP25158892.7A patent/EP4541809A3/en active Pending
- 2017-03-29 CN CN201780021384.7A patent/CN109069535B/zh active Active
- 2017-03-29 CN CN202210315642.5A patent/CN114767718A/zh active Pending
- 2017-03-29 EP EP17715426.7A patent/EP3436034B1/en active Active
-
2020
- 2020-04-30 US US16/863,972 patent/US11065276B2/en active Active
-
2021
- 2021-06-02 US US17/337,367 patent/US20210290667A1/en not_active Abandoned
-
2022
- 2022-08-24 AU AU2022221438A patent/AU2022221438B2/en active Active
-
2023
- 2023-06-20 US US18/338,314 patent/US20230381224A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES3027194T3 (en) | 2025-06-13 |
| EP4541809A2 (en) | 2025-04-23 |
| US20200323901A1 (en) | 2020-10-15 |
| AU2022221438B2 (en) | 2024-10-03 |
| CN114767718A (zh) | 2022-07-22 |
| US10682377B2 (en) | 2020-06-16 |
| WO2017167834A1 (en) | 2017-10-05 |
| US20170283890A1 (en) | 2017-10-05 |
| CN109069535A (zh) | 2018-12-21 |
| SG11201807783UA (en) | 2018-10-30 |
| JP2019513722A (ja) | 2019-05-30 |
| US11065276B2 (en) | 2021-07-20 |
| AU2017242541B2 (en) | 2022-06-30 |
| CA3018126A1 (en) | 2017-10-05 |
| FI3436034T3 (fi) | 2025-05-08 |
| JP6993984B2 (ja) | 2022-02-03 |
| EP4541809A3 (en) | 2025-06-25 |
| AU2022221438A1 (en) | 2022-10-06 |
| CN109069535B (zh) | 2022-03-18 |
| US20210290667A1 (en) | 2021-09-23 |
| US20230381224A1 (en) | 2023-11-30 |
| EP3436034A1 (en) | 2019-02-06 |
| AU2017242541A1 (en) | 2018-10-11 |
| EP3436034B1 (en) | 2025-03-26 |
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