SG11201807783UA - Mutant bordetella strains and methods for use - Google Patents
Mutant bordetella strains and methods for useInfo
- Publication number
- SG11201807783UA SG11201807783UA SG11201807783UA SG11201807783UA SG11201807783UA SG 11201807783U A SG11201807783U A SG 11201807783UA SG 11201807783U A SG11201807783U A SG 11201807783UA SG 11201807783U A SG11201807783U A SG 11201807783UA SG 11201807783U A SG11201807783U A SG 11201807783UA
- Authority
- SG
- Singapore
- Prior art keywords
- lille
- international
- subject
- institut
- calmette
- Prior art date
Links
- 241000588807 Bordetella Species 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 208000037883 airway inflammation Diseases 0.000 abstract 2
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000002950 deficient Effects 0.000 abstract 2
- 108010021711 pertactin Proteins 0.000 abstract 2
- 210000002345 respiratory system Anatomy 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102220240796 rs553605556 Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662314843P | 2016-03-29 | 2016-03-29 | |
| PCT/EP2017/057468 WO2017167834A1 (en) | 2016-03-29 | 2017-03-29 | Mutant bordetella strains and methods for use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201807783UA true SG11201807783UA (en) | 2018-10-30 |
Family
ID=58488973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807783UA SG11201807783UA (en) | 2016-03-29 | 2017-03-29 | Mutant bordetella strains and methods for use |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10682377B2 (enExample) |
| EP (2) | EP4541809A3 (enExample) |
| JP (1) | JP6993984B2 (enExample) |
| CN (2) | CN109069535B (enExample) |
| AU (2) | AU2017242541B2 (enExample) |
| DK (1) | DK3436034T3 (enExample) |
| ES (1) | ES3027194T3 (enExample) |
| FI (1) | FI3436034T3 (enExample) |
| SG (1) | SG11201807783UA (enExample) |
| WO (1) | WO2017167834A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3800244A1 (en) * | 2006-03-10 | 2021-04-07 | Institut Pasteur de Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| WO2010125014A1 (en) | 2009-04-28 | 2010-11-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
| CN109069535B (zh) * | 2016-03-29 | 2022-03-18 | 里尔巴斯德研究所 | 突变型博德特氏菌属菌株及其使用方法 |
| CA3077428A1 (en) * | 2017-10-18 | 2019-04-25 | Institut Pasteur De Lille | Bordetella strains expressing serotype 3 fimbriae |
| JP2023540453A (ja) | 2020-08-14 | 2023-09-25 | イリアド バイオテクノロジーズ，リミテッド ライアビリティ カンパニー | 凍結乾燥生ボルデテラワクチン |
| CA3195783A1 (en) * | 2020-11-17 | 2022-05-27 | Keith Rubin | Treatment and prevention of neuropathology associated with neurodegenerative diseases |
| KR20250038747A (ko) | 2022-07-22 | 2025-03-19 | 인스티튜트 내셔날 드 라 싼테 에 드 라 리셰르셰 메디칼르 | 만성 폐쇄성 폐질환의 치료를 위한 보르데텔라 균주의 용도 |
| WO2025257397A1 (en) | 2024-06-14 | 2025-12-18 | Institut National de la Santé et de la Recherche Médicale | Live attenuated bordetella vaccines capable of producing and secreting heterologous antigens |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6713072B1 (en) | 1987-11-02 | 2004-03-30 | Chiron S.R.L. | Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
| GB9115332D0 (en) * | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| FR2718750B1 (fr) | 1994-04-19 | 1996-06-14 | Pasteur Institut | Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants. |
| CA2188424A1 (en) * | 1994-04-28 | 1995-11-09 | Akihiro Suehara | Method of separating protective components of bordetella pertussis |
| FR2754543B1 (fr) * | 1996-10-11 | 1998-12-31 | Pasteur Institut | Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires |
| FR2840319B1 (fr) | 2002-05-30 | 2004-08-20 | Pasteur Institut | Souches de bordetella rendues deficientes par attenuation genetique |
| WO2004091519A2 (en) | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Methods of preventing or treating respiratory conditions |
| EP3800244A1 (en) | 2006-03-10 | 2021-04-07 | Institut Pasteur de Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| WO2008058396A1 (en) | 2006-11-15 | 2008-05-22 | Folia Biotech Inc. | Papaya mosaic virus-based vaccines for influenza |
| EP2134359A4 (en) | 2007-02-23 | 2010-06-16 | Penn State Res Found | USE OF A NONVIRULENT BORDETELLA MUTANT AS LIVING VACCINE VECTOR |
| AU2008266910A1 (en) | 2007-06-18 | 2008-12-24 | Hemispherx Biopharma, Inc. | Early intervention of viral infections with immune activators |
| WO2010125014A1 (en) | 2009-04-28 | 2010-11-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
| CN102802665B (zh) | 2009-06-15 | 2015-11-25 | 新加坡国立大学 | 流感疫苗、组合物及使用方法 |
| CA2854110C (en) * | 2011-11-02 | 2019-06-25 | Institut Pasteur De Lille | Effect of an attenuated bordetella strain against allergic disease |
| CN102793915B (zh) * | 2012-07-25 | 2013-10-23 | 天津康希诺生物技术有限公司 | 一种无细胞百日咳疫苗的生产方法 |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| CN109069535B (zh) * | 2016-03-29 | 2022-03-18 | 里尔巴斯德研究所 | 突变型博德特氏菌属菌株及其使用方法 |
-
2017
- 2017-03-29 CN CN201780021384.7A patent/CN109069535B/zh active Active
- 2017-03-29 CN CN202210315642.5A patent/CN114767718A/zh active Pending
- 2017-03-29 ES ES17715426T patent/ES3027194T3/es active Active
- 2017-03-29 JP JP2018551960A patent/JP6993984B2/ja active Active
- 2017-03-29 FI FIEP17715426.7T patent/FI3436034T3/fi active
- 2017-03-29 AU AU2017242541A patent/AU2017242541B2/en active Active
- 2017-03-29 WO PCT/EP2017/057468 patent/WO2017167834A1/en not_active Ceased
- 2017-03-29 US US15/472,436 patent/US10682377B2/en active Active
- 2017-03-29 DK DK17715426.7T patent/DK3436034T3/da active
- 2017-03-29 EP EP25158892.7A patent/EP4541809A3/en active Pending
- 2017-03-29 SG SG11201807783UA patent/SG11201807783UA/en unknown
- 2017-03-29 EP EP17715426.7A patent/EP3436034B1/en active Active
-
2020
- 2020-04-30 US US16/863,972 patent/US11065276B2/en active Active
-
2021
- 2021-06-02 US US17/337,367 patent/US20210290667A1/en not_active Abandoned
-
2022
- 2022-08-24 AU AU2022221438A patent/AU2022221438B2/en active Active
-
2023
- 2023-06-20 US US18/338,314 patent/US20230381224A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4541809A3 (en) | 2025-06-25 |
| US20200323901A1 (en) | 2020-10-15 |
| EP3436034A1 (en) | 2019-02-06 |
| AU2022221438A1 (en) | 2022-10-06 |
| AU2022221438B2 (en) | 2024-10-03 |
| US20230381224A1 (en) | 2023-11-30 |
| EP4541809A2 (en) | 2025-04-23 |
| CN109069535B (zh) | 2022-03-18 |
| JP2019513722A (ja) | 2019-05-30 |
| CA3018126A1 (en) | 2017-10-05 |
| US20170283890A1 (en) | 2017-10-05 |
| US11065276B2 (en) | 2021-07-20 |
| FI3436034T3 (fi) | 2025-05-08 |
| CN109069535A (zh) | 2018-12-21 |
| DK3436034T3 (da) | 2025-05-12 |
| US10682377B2 (en) | 2020-06-16 |
| AU2017242541A1 (en) | 2018-10-11 |
| US20210290667A1 (en) | 2021-09-23 |
| CN114767718A (zh) | 2022-07-22 |
| JP6993984B2 (ja) | 2022-02-03 |
| ES3027194T3 (en) | 2025-06-13 |
| AU2017242541B2 (en) | 2022-06-30 |
| WO2017167834A1 (en) | 2017-10-05 |
| EP3436034B1 (en) | 2025-03-26 |
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