DK3416984T3 - Kimært hunde-anti-cd20-antistof - Google Patents

Kimært hunde-anti-cd20-antistof Download PDF

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Publication number
DK3416984T3
DK3416984T3 DK17706644.6T DK17706644T DK3416984T3 DK 3416984 T3 DK3416984 T3 DK 3416984T3 DK 17706644 T DK17706644 T DK 17706644T DK 3416984 T3 DK3416984 T3 DK 3416984T3
Authority
DK
Denmark
Prior art keywords
chimered
antibody
dog anti
dog
chimered dog
Prior art date
Application number
DK17706644.6T
Other languages
English (en)
Inventor
James David Pancook
Original Assignee
Elanco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elanco Us Inc filed Critical Elanco Us Inc
Application granted granted Critical
Publication of DK3416984T3 publication Critical patent/DK3416984T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK17706644.6T 2016-02-18 2017-02-10 Kimært hunde-anti-cd20-antistof DK3416984T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662296729P 2016-02-18 2016-02-18
PCT/US2017/017337 WO2017142800A1 (en) 2016-02-18 2017-02-10 Chimeric canine anti-cd20 antibody

Publications (1)

Publication Number Publication Date
DK3416984T3 true DK3416984T3 (da) 2021-04-26

Family

ID=58098709

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17706644.6T DK3416984T3 (da) 2016-02-18 2017-02-10 Kimært hunde-anti-cd20-antistof

Country Status (14)

Country Link
US (4) US10519244B2 (da)
EP (1) EP3416984B1 (da)
JP (1) JP6661019B2 (da)
KR (1) KR102131544B1 (da)
CN (1) CN108699152B (da)
AU (1) AU2017219596B2 (da)
BR (1) BR112018016367A2 (da)
CA (1) CA3014461C (da)
DK (1) DK3416984T3 (da)
EA (1) EA039434B1 (da)
ES (1) ES2868650T3 (da)
MX (2) MX2018009955A (da)
NZ (1) NZ744192A (da)
WO (1) WO2017142800A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108699152B (zh) * 2016-02-18 2022-08-19 伊兰科美国公司 嵌合犬抗cd20抗体
MX2020001707A (es) * 2017-08-15 2020-03-20 Kindred Biosciences Inc Variantes igg fc para uso veterinario.
JP2021059499A (ja) 2019-10-03 2021-04-15 日本全薬工業株式会社 イヌcd20に対するモノクローナル抗体又は抗体フラグメント
MX2023015152A (es) * 2021-06-17 2024-05-31 Petmedix Ltd Anticuerpos anti-cd20 canino.
WO2023010057A1 (en) * 2021-07-28 2023-02-02 Atreca, Inc. Atrc-101 target expression assay
GB202217993D0 (en) * 2022-11-30 2023-01-11 Petmedix Ltd Therapeutic antibodies
US20240209096A1 (en) 2022-12-27 2024-06-27 Invetx, Inc. Polypeptides with altered binding to neonatal fc receptor (fcrn) and methods of use
WO2024155982A2 (en) 2023-01-20 2024-07-25 Invetx, Inc. Bispecific binding agents for use in companion animals

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101914158A (zh) * 2002-02-14 2010-12-15 免疫医疗公司 抗cd 20抗体及其融合蛋白和使用方法
AR044388A1 (es) * 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
JP4745242B2 (ja) * 2003-05-20 2011-08-10 アプライド モレキュラー エボリューション,インコーポレイテッド Cd20結合分子
CN101945667A (zh) * 2007-12-21 2011-01-12 健泰科生物技术公司 利妥昔单抗不应性类风湿性关节炎患者的疗法
US8569460B2 (en) * 2009-03-25 2013-10-29 Vet Therapeutics, Inc. Antibody constant domain regions and uses thereof
EP2496604B1 (en) * 2009-11-06 2017-08-23 IDEXX Laboratories, Inc. Canine anti-cd20 antibodies
WO2011109108A1 (en) 2010-03-04 2011-09-09 Vet Therapeutics Inc. Monoclonal antibodies directed to cd20
GB201114858D0 (en) * 2011-08-29 2011-10-12 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of using the same
US20140294819A1 (en) * 2011-10-13 2014-10-02 Nvip Pty Ltd Canine/feline cd20 binding epitope and compositions for binding thereto
EP3378489A1 (en) * 2011-10-26 2018-09-26 Elanco Tiergesundheit AG Monoclonal antibodies and methods of use
JP6749312B2 (ja) * 2014-07-31 2020-09-02 アムゲン リサーチ (ミュンヘン) ゲーエムベーハーAMGEN Research(Munich)GmbH 最適化された種間特異的二重特異性単鎖抗体コンストラクト
CN108699152B (zh) * 2016-02-18 2022-08-19 伊兰科美国公司 嵌合犬抗cd20抗体

Also Published As

Publication number Publication date
US20230257476A1 (en) 2023-08-17
US10519244B2 (en) 2019-12-31
WO2017142800A1 (en) 2017-08-24
EP3416984B1 (en) 2021-03-31
ES2868650T3 (es) 2021-10-21
BR112018016367A2 (pt) 2019-01-22
AU2017219596B2 (en) 2019-07-04
US20200131273A1 (en) 2020-04-30
JP6661019B2 (ja) 2020-03-11
NZ744192A (en) 2019-11-29
AU2017219596A1 (en) 2018-07-19
EP3416984A1 (en) 2018-12-26
CA3014461C (en) 2023-02-28
CA3014461A1 (en) 2017-08-24
KR102131544B1 (ko) 2020-07-07
MX2022014375A (es) 2022-12-15
JP2019507128A (ja) 2019-03-14
US20210163618A1 (en) 2021-06-03
EA039434B1 (ru) 2022-01-27
CN108699152B (zh) 2022-08-19
MX2018009955A (es) 2018-11-29
EA201891499A1 (ru) 2019-01-31
KR20180096804A (ko) 2018-08-29
US10941206B2 (en) 2021-03-09
CN108699152A (zh) 2018-10-23
US20190194342A1 (en) 2019-06-27

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