DK3414257T3 - Fremgangsmåde til fremstilling af liraglutid under anvendelse af BAL linker - Google Patents

Fremgangsmåde til fremstilling af liraglutid under anvendelse af BAL linker Download PDF

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Publication number
DK3414257T3
DK3414257T3 DK17750508.8T DK17750508T DK3414257T3 DK 3414257 T3 DK3414257 T3 DK 3414257T3 DK 17750508 T DK17750508 T DK 17750508T DK 3414257 T3 DK3414257 T3 DK 3414257T3
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DK
Denmark
Prior art keywords
liraglutide
preparation
bal
linker
bal linker
Prior art date
Application number
DK17750508.8T
Other languages
English (en)
Inventor
Palomera Fernando Albericio
Lopez Daniel Carbajo
Original Assignee
Polypeptide Laboratories Holding Ppl Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polypeptide Laboratories Holding Ppl Ab filed Critical Polypeptide Laboratories Holding Ppl Ab
Application granted granted Critical
Publication of DK3414257T3 publication Critical patent/DK3414257T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
DK17750508.8T 2016-02-11 2017-02-06 Fremgangsmåde til fremstilling af liraglutid under anvendelse af BAL linker DK3414257T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662293830P 2016-02-11 2016-02-11
EP16155165.0A EP3205664A1 (en) 2016-02-11 2016-02-11 Method for preparation of liraglutide using bal linker
PCT/SE2017/000008 WO2017138855A1 (en) 2016-02-11 2017-02-06 Method for preparation of liraglutide using bal linker

Publications (1)

Publication Number Publication Date
DK3414257T3 true DK3414257T3 (da) 2023-08-21

Family

ID=55435973

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17750508.8T DK3414257T3 (da) 2016-02-11 2017-02-06 Fremgangsmåde til fremstilling af liraglutid under anvendelse af BAL linker

Country Status (5)

Country Link
EP (2) EP3205664A1 (da)
DK (1) DK3414257T3 (da)
ES (1) ES2954660T3 (da)
HU (1) HUE063747T2 (da)
WO (1) WO2017138855A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210277051A1 (en) * 2018-06-22 2021-09-09 Zhejiang Peptites Biotech Co., Ltd. Compound or salt thereof and preparation method and application of same
WO2020127476A1 (en) 2018-12-19 2020-06-25 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
WO2021123228A1 (en) 2019-12-18 2021-06-24 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
CN111892650A (zh) * 2020-07-06 2020-11-06 辽宁药联制药有限公司 一种利拉鲁肽固相合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL192359B1 (pl) 1996-08-30 2006-10-31 Novo Nordisk As Pochodna GLP-1(7-37) lub analogu GLP-1(7-37), środek farmaceutyczny oraz zastosowanie pochodnej GLP-1(7-37) lub analogu GLP-1(7-37)
RU2001128068A (ru) 1999-03-17 2004-02-20 Ново Нордиск А/С (DK) Способ ацилирования пептидов и новые ацилирующие агенты
CN102286092B (zh) * 2011-09-14 2014-01-01 深圳翰宇药业股份有限公司 利拉鲁肽的固相合成方法
WO2014199397A2 (en) * 2013-06-11 2014-12-18 Mylan Laboratories Ltd Process for the preparation of liraglutide
EP3024847A1 (en) * 2013-07-25 2016-06-01 Novartis AG Disulfide cyclic polypeptides for the treatment of heart failure
CN103864918B (zh) * 2014-03-31 2016-08-17 哈尔滨吉象隆生物技术有限公司 一种利拉鲁肽的固相合成方法

Also Published As

Publication number Publication date
WO2017138855A1 (en) 2017-08-17
EP3414257B1 (en) 2023-06-07
EP3205664A1 (en) 2017-08-16
ES2954660T3 (es) 2023-11-23
EP3414257A1 (en) 2018-12-19
EP3414257A4 (en) 2019-11-06
HUE063747T2 (hu) 2024-01-28

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