DK3399035T3 - Fremgangsmåde til fremstilling af et beriget bibliotek - Google Patents

Fremgangsmåde til fremstilling af et beriget bibliotek Download PDF

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Publication number
DK3399035T3
DK3399035T3 DK18161280.5T DK18161280T DK3399035T3 DK 3399035 T3 DK3399035 T3 DK 3399035T3 DK 18161280 T DK18161280 T DK 18161280T DK 3399035 T3 DK3399035 T3 DK 3399035T3
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DK
Denmark
Prior art keywords
procedure
making
enriched library
enriched
library
Prior art date
Application number
DK18161280.5T
Other languages
Danish (da)
English (en)
Inventor
Nils Jakob Vest Hansen
Allan Beck Christensen
Leif Kongskov Larsen
Lars Kolster Petersen
Judith Rasmussen-Dietvorst
Tara Heitner Hansen
Johan Holmkvist
Peter Blakskjaer
Frank Abildgaard Sløk
Original Assignee
Vipergen Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vipergen Aps filed Critical Vipergen Aps
Application granted granted Critical
Publication of DK3399035T3 publication Critical patent/DK3399035T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

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  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK18161280.5T 2010-09-27 2011-09-01 Fremgangsmåde til fremstilling af et beriget bibliotek DK3399035T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10180435 2010-09-27
EP11749853.5A EP2622073B1 (en) 2010-09-27 2011-09-01 A method for making an enriched library

Publications (1)

Publication Number Publication Date
DK3399035T3 true DK3399035T3 (da) 2021-05-17

Family

ID=43629282

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18161280.5T DK3399035T3 (da) 2010-09-27 2011-09-01 Fremgangsmåde til fremstilling af et beriget bibliotek
DK11749853.5T DK2622073T5 (en) 2010-09-27 2011-09-01 Method of Preparing an Enriched Library

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11749853.5T DK2622073T5 (en) 2010-09-27 2011-09-01 Method of Preparing an Enriched Library

Country Status (8)

Country Link
US (2) US20130288929A1 (cg-RX-API-DMAC10.html)
EP (2) EP3399035B1 (cg-RX-API-DMAC10.html)
JP (2) JP6193761B2 (cg-RX-API-DMAC10.html)
CN (1) CN103119165B (cg-RX-API-DMAC10.html)
CA (1) CA2808656C (cg-RX-API-DMAC10.html)
DK (2) DK3399035T3 (cg-RX-API-DMAC10.html)
IL (1) IL224694B (cg-RX-API-DMAC10.html)
WO (1) WO2012041633A1 (cg-RX-API-DMAC10.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103119165B (zh) * 2010-09-27 2017-04-12 威泊根私人有限公司 制备富集文库的方法
WO2014088830A2 (en) * 2012-12-05 2014-06-12 The Regents Of The University Of California Screening of nucleic acid agents via particle display
CN104630202A (zh) * 2013-11-13 2015-05-20 北京大学 一种能够减小微量核酸物质整体扩增时产生偏倚的扩增方法
GB201420852D0 (en) * 2014-11-24 2015-01-07 Genevillage Kft Method
WO2017031378A1 (en) 2015-08-18 2017-02-23 Krusemark Casey J Systems and methods for proteomic activity analysis using dna-encoded probes
KR102516168B1 (ko) 2016-05-02 2023-03-30 엔코디아, 인코포레이티드 암호화 핵산을 사용한 거대분자 분석
EP3472376A4 (en) 2016-06-16 2019-12-18 Richard Edward Watts OLIGONUCLEOTIDE CONTROLLED AND RECORDED COMBINATORY SYNTHESIS OF CODED PROBE MOLECULES
EP3619340A4 (en) 2017-05-02 2021-01-20 Haystack Sciences Corporation OLIGONUCLEOTID-DRIVEN COMBINATORY SYNTHESIS VERIFICATION MOLECULES AND ASSOCIATED MANUFACTURING AND USE PROCESSES
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
MX2020003695A (es) 2017-11-30 2020-08-03 Arrakis Therapeutics Inc Fotosondas de union a acido nucleico y usos de las mismas.
CA3127137A1 (en) * 2019-01-22 2020-07-30 Vipergen Aps A method for screening of an in vitro display library within a cell
EP3963070A4 (en) 2019-04-30 2023-02-22 Encodia, Inc. METHODS OF PREPARATION OF ANALYTES AND RELATED KITS
CN112941634B (zh) * 2019-12-10 2023-09-26 成都先导药物开发股份有限公司 通过dna编码化合物库筛选同时结合多个生物靶标的化合物的方法
EP4330678A1 (en) * 2021-04-26 2024-03-06 Ecole Polytechnique Federale De Lausanne (Epfl) High complexity microcompartment-based interaction screening
GB202317973D0 (en) 2023-11-24 2024-01-10 Nuclera Ltd Use of DNA encoded libraries

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US7479472B1 (en) 1998-10-19 2009-01-20 The Board Of Trustees Of The Leland Stanford Junior University DNA-templated combinatorial library chemistry
PT1423400E (pt) 2001-03-19 2006-12-29 Harvard College Evolução de nova função molecular
CN1539014A (zh) 2001-06-20 2004-10-20 ŦΤ¬ɭ��˾ 模控分子和使用这种分子的方法
ATE447626T1 (de) * 2003-09-18 2009-11-15 Nuevolution As Methode zur gewinnung struktureller informationen kodierter moleküle und zur selektion von verbindungen
CN1898257B (zh) * 2003-12-17 2010-06-23 普雷西斯药品公司 合成编码文库的方法
US7968287B2 (en) * 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2006047791A2 (en) * 2004-10-27 2006-05-04 The Board Of Trustees Of The Leland Stanford Junior University Dna-templated combinatorial library device and method for use
EP1809743B1 (en) * 2004-11-08 2008-12-31 Vipergen APS Structural nucleid acid guided chemical synthesis
US8168381B2 (en) 2004-11-22 2012-05-01 Peter Birk Rasmussen Template directed split and mix systhesis of small molecule libraries
EP2118280B1 (en) * 2007-02-23 2010-12-01 New England Biolabs, Inc. Selection and enrichment of proteins using in vitro compartmentalization
EP2210104A4 (en) * 2007-11-01 2011-02-23 Univ Arizona State CELL-FREE PROCEDURE FOR DETECTING PROTEIN-LIGAND INTERACTIONS
US8153446B2 (en) 2008-05-23 2012-04-10 Kent State University Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems
EP2452195A4 (en) * 2009-07-07 2012-12-05 Agency Science Tech & Res METHOD FOR IDENTIFYING A PAIR OF CONNECTING PARTNERS
CN103119165B (zh) * 2010-09-27 2017-04-12 威泊根私人有限公司 制备富集文库的方法

Also Published As

Publication number Publication date
CN103119165B (zh) 2017-04-12
EP3399035B1 (en) 2021-02-17
CN103119165A (zh) 2013-05-22
US10513700B2 (en) 2019-12-24
WO2012041633A1 (en) 2012-04-05
IL224694A0 (en) 2013-07-31
CA2808656A1 (en) 2012-04-05
JP2013540440A (ja) 2013-11-07
EP3399035A1 (en) 2018-11-07
US20130288929A1 (en) 2013-10-31
IL224694B (en) 2018-08-30
CA2808656C (en) 2019-12-03
DK2622073T5 (en) 2019-02-25
JP6193761B2 (ja) 2017-09-06
DK2622073T3 (da) 2018-07-30
EP2622073A1 (en) 2013-08-07
JP2017060513A (ja) 2017-03-30
EP2622073B1 (en) 2018-04-18
US20170233726A1 (en) 2017-08-17

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